A combined dexamethasone desmopressin test as an early marker of postsurgical recurrence in Cushing's disease

Journal of Clinical Endocrinology and Metabolism

Volumn 94, Issue 6, 2009, Pages 1897-1903

  Castinetti, Frederic ^a   Martinie, Monique ^b   Morange, Isabelle ^a   Dufour, Henry ^a   Sturm, Nathalie ^b   Passagia, Jean Guy ^b   Conte Devolx, Bernard ^a   Chabre, Olivier ^b   Brue, Thierry ^a  

^a TIMONE HOSPITAL   (France)

^b HÔPITAL MICHALLON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CORTICOTROPIN; CORTICOTROPIN RECEPTOR; DESMOPRESSIN; DEXAMETHASONE; HYDROCORTISONE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN DEFICIENCY; COUPLED DEXAMETHASONE DESMOPRESSIN TEST; CUSHING DISEASE; DEXAMETHASONE SUPPRESSION TEST; DISEASE MARKER; ENDOCRINE FUNCTION TEST; FEMALE; FOLLOW UP; FRANCE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; HYPERCORTISOLISM; LOW DRUG DOSE; MALE; MULTICENTER STUDY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; RECURRENT DISEASE; REMISSION; SENSITIVITY AND SPECIFICITY; TRANSSPHENOIDAL SURGERY;

EID: 66749108750     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-2234     Document Type: Article

References (31)

1. Arnaldi G, Angeli A, Atkinson AB, Bertagna X, Cavagnini F, Chrousos GP, Fava GA, Findling JW, Gaillard RC, Grossman AB, Kola B, Lacroix A, Mancini T, Mantero F, Newell-Price J, Nieman LK, Sonino N, Vance ML, Giustina A, Boscaro M 2003 Diagnosis and complications of Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab 88:5593-5602 (Pubitemid 38033020)
2. Trainer PJ, Lawrie HS, Verhelst J, Howlett TA, Lowe DG, Grossman AB, Savage MO, Afshar F, Besser GM 1993 Transsphenoidal resection in Cushing's disease: undetectable serum cortisol as the definition of successful treatment. Clin Endocrinol (Oxf) 38:73-78 (Pubitemid 23030276)
3. Sheehan JM, Lopes MB, Sheehan JP, Ellegala D, Webb KM, Laws Jr ER 2000 Results of transsphenoidal surgery for Cushing's disease in patients with no histologically confirmed tumor. Neurosurgery 47:33-36; discussion, 37-39 (Pubitemid 32047760)
4. Rees DA, Hanna FW, Davies JS, Mills RG, Vafidis J, Scanlon MF 2002 Long-term follow-up results of transsphenoidal surgery for Cushing's disease in a single centre using strict criteria for remission. Clin Endocrinol (Oxf) 56:541-551 (Pubitemid 34429630)
5. Hammer GD, Tyrrell JB, Lamborn KR, Applebury CB, Hannegan ET, Bell S, Rahl R, Lu A, Wilson CB 2004 Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results. J Clin Endocrinol Metab 89:6348-6357 (Pubitemid 39628458)
6. Patil CG, Prevedello DM, Lad SP, Vance ML, Thorner MO, Katznelson L, Laws Jr ER 2008 Late recurrences of Cushing's disease after initial successful transsphenoidal surgery. J Clin Endocrinol Metab 93:358-362
7. Atkinson AB, Kennedy A, Wiggam MI, McCance DR, Sheridan B 2005 Long-term remission rates after pituitary surgery for Cushing's disease: the need for long-term surveillance. Clin Endocrinol (Oxf) 63:549-559 (Pubitemid 41626751)
8. Cavagnini F, Pecori Giraldi F 2001 Epidemiology and follow-up of Cushing's disease. Ann Endocrinol (Paris) 62:168-172
9. Esposito F, Dusick JR, Cohan P, Moftakhar P, McArthur D, Wang C, Swerdloff RS, Kelly DF 2006 Clinical review: early morning cortisol levels as a predictor of remission after transsphenoidal surgery for Cushing's disease. J Clin Endocrinol Metab 91:7-13 (Pubitemid 43069107)
10. Pereira AM, van Aken MO, van Dulken H, Schutte PJ, Biermasz NR, Smit JW, Roelfsema F, Romijn JA 2003 Long-term predictive value of postsurgical cortisol concentrations for cure and risk of recurrence in Cushing's disease. J Clin Endocrinol Metab 88:5858-5864 (Pubitemid 38033063)
11. Estrada J, García-Uría J, Lamas C, Alfaro J, Lucas T, Diez S, Salto L, Barceló B 2001 The complete normalization of the adrenocortical function as the criterion of cure after transsphenoidal surgery for Cushing's disease. J Clin Endocrinol Metab 86:5695-5699 (Pubitemid 33152610)
12. Bochicchio D, Losa M, Buchfelder M 1995 Factors influencing the immediate and late outcome of Cushing's disease treated by transsphenoidal surgery: a retrospective study by the European Cushing's Disease Survey Group. J Clin Endocrinol Metab 80:3114-3120
13. Yap LB, Turner HE, Adams CB, Wass JA 2002 Undetectable postoperative cortisol does not always predict long-term remission in Cushing's disease: a single centre audit. Clin Endocrinol (Oxf) 56:25-31 (Pubitemid 34107318)
14. Rollin GA, Ferreira NP, Junges M, Gross JL, Czepielewski MA 2004 Dynamics of serum cortisol levels after transsphenoidal surgery in a cohort of patients with Cushing's disease. J Clin Endocrinol Metab 89:1131-1139 (Pubitemid 38368401)
15. Pouratian N, Prevedello DM, Jagannathan J, Lopes MB, Vance ML, Laws Jr ER 2007 Outcomes and management of patients with Cushing's disease without pathological confirmation of tumor resection after transsphenoidal surgery. J Clin Endocrinol Metab 92:3383-3388 (Pubitemid 47435309)
16. van Aken MO, de Herder WW, van der Lely AJ, de Jong FH, Lamberts SW 1997 Postoperative metyrapone test in the early assessment of outcome of pituitary surgery for Cushing's disease. Clin Endocrinol (Oxf) 47:145-149 (Pubitemid 27359894)
17. Vignati F, Berselli ME, Loi P 1994 Early postoperative evaluation in patients with Cushing's disease: usefulness of ovine corticotropin-releasing hormone test in the prediction of recurrence of disease. Eur J Endocrinol 130:235-241 (Pubitemid 24117902)
18. Carrasco CA, Coste J, Guignat L, Groussin L, Dugué MA, Gaillard S, Bertagna X, Bertherat J 2008 Midnight salivary cortisol determination for assessing the outcome of transsphenoidal surgery in Cushing's disease. J Clin Endocrinol Metab 93:4728-4734
19. Machado MC, de Sa SV, Domenice S, Fragoso MC, Puglia Jr P, Pereira MA, de Mendonca BB, Salgado LR 2007 The role of desmopressin in bilateral and simultaneous inferior petrosal sinus sampling for differential diagnosis of ACTH-dependent Cushing's syndrome. Clin Endocrinol (Oxf) 66:136-142 (Pubitemid 44952506)
20. Castinetti F, Morange I, Dufour H, Jaquet P, Conte-Devolx B, Girard N, Brue T 2007 Desmopressin test during petrosal sinus sampling: a valuable tool to discriminate pituitary or ectopic ACTH-dependent Cushing's syndrome. Eur J Endocrinol 157:271-277 (Pubitemid 47603530)
21. Terzolo M, Reimondo G, Angeli A 2003 Desmopressin test in mild Cushing syndrome. Arch Intern Med 163:850-851 (Pubitemid 36438059)
22. Valéro R, Vallette-Kasic S, Conte-Devolx B, Jaquet P, Brue T 2004 The desmopressin test as a predictive factor of outcome after pituitary surgery for Cushing's disease. Eur J Endocrinol 151:727-733 (Pubitemid 40090012)
23. Romanholi DJ, Machado MC, Pereira CC, Danilovic DS, Pereira MA, Cescato VA, Neto MB, Musolino NR, de Mendonca BB, Salgado LR 2008 Role for postoperative cortisol response to desmopressin in predicting the risk for recurrent Cushing's disease. Clin Endocrinol (Oxf) 69:117-122
24. Losa M, Mortini P, Dylgjeri S, Barzaghi R, Franzin A, Mandelli C, Giovanelli M 2001 Desmopressin stimulation test before and after pituitary surgery in patients with Cushing's disease. Clin Endocrinol (Oxf) 55:61-68 (Pubitemid 34204300)
25. Colombo P, Dall'Asta C, Barbetta L, Re T, Passini E, Faglia G, Ambrosi B 2000 Usefulness of the desmopressin test in the postoperative evaluation of patients with Cushing's disease. Eur J Endocrinol 143:227-234 (Pubitemid 30622357)
26. Colombo P, Passini E, Re T, Faglia G, Ambrosi B 1997 Effect of desmopressin on ACTH and cortisol secretion in states of ACTH excess. Clin Endocrinol (Oxf) 46:661-668 (Pubitemid 27304450)
27. de Keyzer Y, Rene P, Beldjord C, Lenne F, Bertagna X 1998 Overexpression of vasopressin (V3) and corticotrophin-releasing hormone receptor genes in corticotroph tumours. Clin Endocrinol (Oxf) 49:475-482 (Pubitemid 28475340)
28. Nieman LK, Biller BM, Findling JW, Newell-Price J, Savage MO, Stewart PM, Montori VM 2008 The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 93:1526-1540
29. Newell-Price J, Trainer P, Besser M, Grossman A 1998 The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. Endocr Rev 19:647-672 (Pubitemid 28467716)
30. Dall'asta C, Barbetta L, Bonavina L, Beck-Peccoz P, Ambrosi B 2004 Recurrence of Cushing's disease preceded by the reappearance of ACTH and cortisol responses to desmopressin test. Pituitary 7:183-188 (Pubitemid 43336607)
31. Chabot V, de Keyzer Y, Gebhard S, Uské A, Bischof-Delaloye A, Rey F, Dusmet M, Gomez F 1998 Ectopic ACTH Cushing's syndrome: V3 vasopressin receptor but not CRH receptor gene expression in a pulmonary carcinoid tumor. Horm Res 50:226-231 (Pubitemid 28552529)