High prevalence of vertebral deformities in COPD patients: Relationship to disease severity

European Respiratory Journal

Volumn 33, Issue 5, 2009, Pages 1018-1024

  Kjensli, A ^a,d   Falch, J A ^b   Ryg, M ^a   Blenk, T ^c   Armbrecht, G ^c   Diep, L M ^b   Ellingsen, I ^a  

^a Glittreklinikken   (Norway)

^b AKER UNIVERSITY HOSPITAL   (Norway)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d Charité Universitatsmedizin ^*  (Norway)

Author keywords

Chronic obstructive pulmonary disease; Prevalence; Systemic steroid therapy; Vertebral deformities; Vertebral fractures

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CORTICOSTEROID DERIVATIVE; PREDNISOLONE; VITAMIN D;

ADULT; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HORMONE SUBSTITUTION; HUMAN; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; VERTEBRA MALFORMATION;

ADMINISTRATION, ORAL; ADRENAL CORTEX HORMONES; AGED; AGED, 80 AND OVER; BONE DENSITY; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; MALE; MIDDLE AGED; POISSON DISTRIBUTION; PREVALENCE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SPINE;

EID: 66749099498     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00073908     Document Type: Article

References (22)

1. McEvoy CE, Ensrud KE, Bender E, et al. Association between corticosteroid use and vertebral fractures in older men with chronic obstructive pulmonary disease. Am J Respir Grit Care Med 1998; 157: 704-709.
2. Bolton CE, Ionescu AA, Shiels KM, et al. Associated loss of fat-free mass and bone mineral density in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004; 170: 1286-1293.
3. Kjensli A, Mowinckel P, Ryg MS, Falch JA. Low bone mineral density is related to severity of chronic obstructive pulmonary disease. Bone 2007; 40: 493-497.
4. O'Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ. The prevalence of vertebral deformity in European men and women: The European Vertebral Osteoporosis Study. J Bone Miner Res 1996; 11: 1010-1018.
5. Cooper C, Melton LJ. Vertebral fractures. How large is the silent epidemic? BMJ 1992; 304: 793-794.
6. Williams AL, Al-Busaidi A, Sparrow PJ, Adams JE, Whitehouse RW. Under-reporting of osteoporotic vertebral fractures on computed tomography. Eur J Radiol 2009; 69:179-183.
7. Fink HA,Milavetz DL,Palermo L, et al. What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res 2005; 20: 1216-1222.
8. Jorgensen NR, Schwarz P, Holme I, Henriksen BM, Petersen LJ, Backer V. The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease: a cross sectional study. Respir Med 2007; 101: 177-185.
9. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault J-C. Lung volumes and forced venti- latory flows. Report working party standardization of lung function tests European community for steel and coal. Eur Respir J 1993; 6: Suppl. 16, 5-40.
10. Rabe KF, Hurd S, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007; 176: 532-555.
11. Gulsvik A, Bakke PS. Kronisk obstruktiv lungesykdom. In: Lungesykdommer. En basal innforing. 2nd Edn. Oslo, Fagbokforlaget, 2004; pp. 131-44.
12. Armbrecht G, Blenk T, Chesnut CH III, et al. Vertebral fracture diagnosis in the multinational BONE study of oral ibandronate: quality management in radiology. J Clin Densitom 2008; 11: 221-231.
13. Papaioannou A, Parkinson W, Ferko N, et al. Prevalence of vertebral fracture among patients with chronic obstructive pulmonary disease in Canada. Osteoporos Int 2003; 14: 913-917.
14. Walsh LJ, Lewis SA, Wong CA, et al. The impact of oral corticosteroid use on bone mineral density and vertebral fracture. Am J Respir Crit Care Med 2002; 166: 691-695.
15. Riancho JA, Macias JG, Del Arco C, Amado JA, Freianes J, Anton MA. Vertebral compression fractures and mineral metabolism in chronic obstructive lung disease. Thorax 1987; 42: 962-966.
16. Michaelsson K, Baron JA, Farahmand BY, et al. Hormone replacement therapy and risk of hip fracture: population based case-control study. The Swedish Hip Fracture Study Group. BMJ 1998; 316: 1858-1863.
17. Gallacher SJ, Gallagher AP, McQuillian C, Mitchell PJ, Dixon T. The prevalence of vertebral fracture amongst patients presenting with non-vertebral fractures.Osteoporos Int 2007; 18: 185-192.
18. Yang IA, Fong KM, Sim EH, Black PN, Lasserson TJ. Inhaled corticosteroids for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2007; 2:CD002991.
19. Melton III LJ, Atkinson EJ, Cooper C, O'Fallon WM, Riggs BL. Verteral fractures predict subsequent fractures. Osteoporos Int 1999; 10: 214-221.
20. Hasserius R, Karlsson MK, Nilsson BE, Redlund-Johnell I, Johnell O. Prevalent vertebral deformities predict increased mortality and increased fracture rate in both men and women: a 10-year population-based study of 598 individuals from the Swedish cohort in the European Vertebral Osteoporosis Study. Osteoporos Int 2003; 14: 61-68.
21. Leech JA, Dulberg C, Kellie S, Pattee L, Gay J. Relationship of lung function to severity of osteoporosis in women. Am Rev Respir Dis 1990; 141: 68-71.
22. Falch J, Bentzen H, Dahl AA. Smerter, funksjonsnivå og emosjonelle forhold hos kvinner med osteoporose og vertebrale brudd [Pain, functional level and emotional problems of women with osteoporosis and vertebral fractures]. Tidsskr Nor Lxgeforen 2003; 123: 3355-3357.