Membrane-dependent interaction of factor Xa and prothrombin with factor Va in the prothrombinase complex

Biochemistry

Volumn 48, Issue 22, 2009, Pages 5034-5041

  Qureshi, Shabir H ^a   Yang, Likui ^a   Manithody, Chandrashekhara ^a   Rezaie, Alireza R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION COMPLEX; AFFINITY INTERACTIONS; BINDING STUDIES; CATALYTIC ACTIVITY; COFACTOR; COMPETITIVE KINETICS; CONFORMATIONAL CHANGE; FACTOR XA; INITIAL RATE; NEGATIVELY CHARGED MEMBRANES; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; PROTEIN COMPONENTS; PROTHROMBINASE; PROTHROMBINASE REACTION;

AMINES; COMPETITION; GLYCOPROTEINS;

PHOSPHOLIPIDS;

4 CARBOXYGLUTAMIC ACID; AMINO ACID; ARGININE; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; FLUORESCENT DYE; GLUTAMINE; GLYCINE; HIRUDIN; IODOACETAMIDE; OREGON GREEN; PEPTIDE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PROTEINASE; PROTHROMBIN; THROMBOMODULIN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CELL MEMBRANE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KRINGLE DOMAIN; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE;

1-CARBOXYGLUTAMIC ACID; BINDING, COMPETITIVE; CELL LINE; EPIDERMAL GROWTH FACTOR; FACTOR V; FACTOR VA; FACTOR XA; HUMANS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTHROMBIN; SEQUENCE DELETION; STATIC ELECTRICITY; SUBSTRATE SPECIFICITY; THROMBOPLASTIN;

EID: 66649138898     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900240g     Document Type: Article

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