Altered interactions within FY/AtCPSF complexes required for Arabidopsis FCA-mediated chromatin silencing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 21, 2009, Pages 8772-8777

  Manzano, David ^a,c   Marquardt, Sebastian ^a   Jones, Alexandra M E ^b   Bäurle, Isabel ^a   Liu, Fuquan ^a   Dean, Caroline ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b SAINSBURY LABORATORY   (United Kingdom)

^c CSIC   (Spain)

Author keywords

Flowering; Gene silencing; RNA processing

Indexed keywords

PROTEIN FCA; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ARABIDOPSIS; ARTICLE; CHROMATIN; FY GENE; NONHUMAN; PLANT GENE; PRIORITY JOURNAL; RNA PROCESSING;

ALLELES; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CHROMATIN; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; DNA METHYLATION; GENE EXPRESSION REGULATION, PLANT; GENE SILENCING; MADS DOMAIN PROTEINS; MRNA CLEAVAGE AND POLYADENYLATION FACTORS; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN ISOFORMS; RNA, PLANT; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC;

ARABIDOPSIS;

EID: 66649124882     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903444106     Document Type: Article

References (31)

1. Moazed D (2009) Small RNAs in transcriptional gene silencing and genome defence. Nature 457:413-420.
2. Michaels SD, Amasino RM (1999) FLOWERING LOCUS C encodes a novel MADS domain protein that acts as a repressor of flowering. Plant Cell 11:949-956.
3. Michaels SD, Amasino RM (2001) Loss of FLOWERING LOCUS C activity eliminates the late- flowering phenotype of FRIGIDA and autonomous pathway mutations but not responsiveness to vernalization. Plant Cell 13:935-941. (Pubitemid 32375911)
4. Sheldon CC, et al. (1999) The FLF MADS box gene: A repressor of flowering in Arabidopsis regulated by vernalization and methylation. Plant Cell 11:445-458.
5. Bäurle I, Smith L, Baulcombe DC, Dean C (2007) Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing. Science 318:109-112. (Pubitemid 47538044)
6. Bäurle I, Dean C (2006) The timing of developmental transitions in plants. Cell 125:655-664.
7. Bäurle I, Dean C (2008) Differential interactions of the autonomous pathway RRM proteins and chromatin regulators in the silencing of Arabidopsis targets. PLoS ONE 3:e2733.
8. Simpson GG, Dijkwel PP, Quesada V, Henderson I, Dean C (2003) FY is an RNA 3′ end-processing factor that interacts with FCA to control the Arabidopsis floral transition. Cell 113:777-787. (Pubitemid 36724941)
9. Henderson IR, Liu F, Drea S, Simpson GG, Dean C (2005) An allelic series reveals essential roles for FY in plant development in addition to flowering-time control. Development (Cambridge, UK) 132:3597-3607. (Pubitemid 41301098)
10. Liu F, et al. (2007) The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC. Mol Cell 28:398-407. (Pubitemid 350030571)
11. Herr AJ, Molnar A, Jones A, Baulcombe DC (2006) Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis. Proc Natl Acad Sci USA 103:14994-15001. (Pubitemid 44583153)
12. Bayne EH, et al. (2008) Splicing factors facilitate RNAi-directed silencing in fission yeast. Science 322:602-606.
13. Ohnacker M, Barabino SM, Preker PJ, Keller W (2000) The WD-repeat protein pfs2p bridges two essential factors within the yeast pre-mRNA 3′-end-processing complex. EMBO J 19:37-47. (Pubitemid 30009223)
14. Zhao J, Hyman L, Moore C (1999) Formation of mRNA 3′ ends in eukaryotes: Mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev 63:405-445. (Pubitemid 29264977)
15. Yao Y, Song L, Katz Y, Galili G (2002) Cloning and characterization of Arabidopsis homologues of the animal CstF complex that regulates 3′ mRNA cleavage and polyadenylation. J Exp Bot 53:2277-2278. (Pubitemid 35273849)
16. Smith LM, (2007)An SNF2 protein associated with nuclear RNA silencing and the spread of a silencing signal between cells in Arabidopsis. Plant Cell 19:1507-1521. (Pubitemid 47025373)
17. Rigaut G, et al. (1999) A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol 17:1030-1032. (Pubitemid 29474865)
18. Rohila JS, Chen M, Cerny R, Fromm ME (2004) Improved tandem affinity purification tag and methods for isolation of protein heterocomplexes from plants. Plant J 38:172-181. (Pubitemid 38448454)
19. Hunt AG, et al. (2008) Arabidopsis mRNA polyadenylation machinery: Comprehensive analysis of protein-protein interactions and gene expression profiling. BMC Genomics 9:220.
20. Xing D, Zhao H, Li QQ (2008) Arabidopsis CLP1-SIMILAR PROTEIN3, an ortholog of human polyadenylation factor CLP1, functions in gametophyte, embryo, and postembryonic development. Plant Physiol 148:2059-2069. (Pubitemid 352847481)
21. Jang YH, Lee JH, Kim JK (2008) Abscisic acid does not disrupt either the Arabidopsis FCA-FY interaction or its rice counterpart in vitro. Plant Cell Physiol 49:1898-1901.
22. Xu R, et al. (2006) The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis Plant Mol Biol 61:799-815. (Pubitemid 44168595)
23. Macknight R, et al. (1997) FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains. Cell 89:737-745. (Pubitemid 27516176)
24. Tzafrir I, ET AL. (2004) Identification of genes required for embryo development in Arabidopsis. Plant Physiol 135:1206-1220. (Pubitemid 39009371)
25. Quesada V, Macknight R, Dean C, Simpson GG (2003) Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time. EMBO J 22:3142-3152. (Pubitemid 36758634)
26. Dichtl B, Aasland R, Keller W (2004) Functions for S. cerevisiae Swd2p in 3′ end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA 10:965-977. (Pubitemid 38669769)
27. Rozenblatt-Rosen O, et al. (2009) The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors. Proc Natl Acad Sci USA 106:755-760.
28. Nordick K, Hoffman MG, Betz JL, Jaehning JA (2008) Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II. Eukaryot Cell 7:1158-1167.
29. Sudol M, Hunter T (2000) New wrinkles for an old domain. Cell 103:1001-1004. (Pubitemid 32037388)
30. Ito S, et al. (2001) A novel WD40 repeat protein, WDC146, highly expressed during spermatogenesis in a stage-specific manner. Biochem Biophys Res Commun 280:656-663. (Pubitemid 32924481)
31. De Lucia F, Crevillen P, Jones AM, Greb T, Dean C (2008) A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. Proc Natl Acad Sci USA 105:16831-16836.