99mTc-sestamibi uptake in rat skeletal muscle and heart: Physiological determinants and correlations

Physiological Research

Volumn 58, Issue 1, 2009, Pages 21-28

  Arsos, G ^a   Kyparos, A ^b,c   Moralidis, E ^a   Kyparos, D ^b   Georga, S ^a   Sotiriadou, S ^b   Matziari, C ^b   Karakatsanis, C ^a  

^a Aristotle University of Thessaloniki   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c UNIVERSITY OF THESSALY   (Greece)

Author keywords

99mTc sestamibi uptake; Mitochondria; Myocardium; Skeletal muscle

Indexed keywords

METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT;

ANIMAL; ARTICLE; BODY WEIGHT; COMPARATIVE STUDY; HEART; HEART MITOCHONDRION; HEART MUSCLE; HEART SCINTISCANNING; HINDLIMB; INTRAVENOUS DRUG ADMINISTRATION; MALE; METABOLISM; METHODOLOGY; MUSCLE MITOCHONDRION; ORGAN SIZE; RAT; SCINTISCANNING; SKELETAL MUSCLE; TISSUE DISTRIBUTION; WISTAR RAT;

ANIMALS; BODY WEIGHT; HEART; HINDLIMB; INJECTIONS, INTRAVENOUS; MALE; MITOCHONDRIA, HEART; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; MYOCARDIAL PERFUSION IMAGING; MYOCARDIUM; ORGAN SIZE; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; TECHNETIUM TC 99M SESTAMIBI; TISSUE DISTRIBUTION;

EID: 66549130490     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Actolun C, Bayhan H, Kir M: Clinical experience with Tc-99m MIBI imaging in patients with malignant tumors. Preliminary results and comparison with Tl-201. Clin Nucl Med 17: 171-176, 1992.
2. Armstrong RB, Phelps RO: Muscle fiber type composition of the rat hindlimb. Am J Anat 171: 259-272, 1984.
3. Backus M, Piwnicka-Worms D, Hackett D, Kronauge J, Lieberman M, Ingram P, Lefurgey A: Microprobe analysis of Tc-MIBI ine heart cells: calculation of mitochondrial membrane potential. Am J Physiol 256: C178-C187, 1993.
4. Bangsbo J, Johansen L, Quistorff B, Saltin B: NMR and analytic biochemical evaluation of CrP and nucleotides in the human calf during muscle contraction. J Appl Physiol 74: 2034-2039, 1993.
5. m-sestamibi uptake in the leg muscles and in the myocardium in patients with intermittent claudication. Angiology 44: 971-976, 1993.
6. Chang YY, Lee CH, Lan MY, Wu HS, Chang CC, Liu JS: A new noninvasive test to detect mitochondrial dysfunction of skeletal muscles in progressive supranuclear palsy. Ann N Y Acad Sci 1042: 76-81, 2005.
7. Chen CC, Meadows B, Regis J, Kalafsky G, Fojo T, Carrasquillo JA, Bates SE: Detection of in vivo P-glycoprotein inhibition by PSC-833 using Tc-99m sestamibi. Clin Cancer Res 4: 545-552, 1997.
8. Cittanti C, Colamussi P, Giganti M, Orlandi C, Uccelli L, Manfrini S, Azzena G, Piffanelli A: Technetium-99m sestamibi leg scintigraphy for non-invasive assessment of propionyl-L-carnitine induced changes in skeletal muscle metabolism. Eur J Nucl Med 24: 762-766, 1997.
9. 99mTc sestamibi - a new agent for parathyroid imaging. Nucl Med Commun 10: 791-794, 1989.
10. Crane P, Laliberte R, Heminway S, Thoolen M, Orlandi CL: Effect of mitochondrial viability and metabolism on technetium-99-sestamibi myocardial retention. Eur J Nucl Med 20: 20-25, 1993.
11. Davies KJA, Packer L, Brooks GA: Biochemical adaptation of mitochondria, muscle and whole-animal respiration to endurance training. Arch Biochem Biophys 209: 539-554, 1981.
12. De Visser M, Reimers CD: Muscle Imaging. In: Myology, Basic and Clinical. Engel AG, Franzini-Armstrong C (eds), McGraw-Hill, New York, 1994, pp 795-806.
13. Delp MD, Manning RO, Bruckner JV, Armstrong RB: Distribution of cardiac output during diurnal changes of activity in rats. Am J Physiol 261: H1487-H1493, 1991.
14. Else PL, Hulbert AJ: Mammals: an allometric study of metabolism at tissue and mitochondrial level. Am J Physiol 248: R415-R421, 1985.
15. Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 84: 265-269, 1987.
16. Kayar SR, Conley KE, Claassen H, Hoppeler H. Capillarity and mitochondrial distribution in rat myocardium following exercise training. J Exp Biol 120: 189-199, 1986.
17. 99mTc-sestamibi uptake. Physiol Res 55: 653-659, 2006.
18. Lexell J, Taylor C, Sjöström M: Analysis of sampling errors in biopsy techniques using data from whole muscle cross sections. J Appl Physiol 59: 1228-1235, 1985.
19. Maddahi J, Kiat H, Van Train KF Prigent F, Friedman J, Garcia EV, Alazraki N, Depuey EG, Nichols K, Berman DS: Myocardial perfusion imaging with technetium-99m sestamibi SPECT in the evaluation of coronary artery disease. Am J Cardiol 66: 55E-62E, 1990.
20. McDonald KS, Delp MD, Fitts RH: Effect of hindlimb unweighting on tissue blood flow in the rat. J Appl Physiol 54: 1242-1248, 1983.
21. Nakatani T, Nakashima T, Kita T, Hirofuji C, Itoh K, Itoh M, Ishihara A: Succinate dehydrogenase activities of fibers in the rat extensor digitorum longus, soleus, and cardiac muscles. Arch Histol Cytol 62: 393-399, 1999.
22. Nuutila P, Kalliokoski K: Use of positron emission tomography in the assessment of skeletal muscle and tendon metabolism and perfusion. Scand J Med Sci Sports 10: 346-350, 2000.
23. 99mTc-MIBI uptakes on planar images with those in excised rats organs. Nucl Med Commun 24: 47-54, 2003.
24. Page E, McCallister LP: Quantitative electron microscopic description of heart muscle cells. Application to normal, hypertrophied and thyroxin-stimulated hearts. Am J Cardiol 31: 172-181, 1973.
25. Piwnica-Worms D, Kronauge JF, Chiu ML: Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium(I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence. Circulation 82: 1826-1838, 1990.
26. Saltin B, Gollnick PD: Skeletal muscle adaptability: significance for metabolism and performance. In: Handbook of Physiology. Section 10: Skeletal Muscle. Peachy LD, Adrian RH Geiger SR (eds), Bethesda, Maryland, 1983, pp 555-631.
27. 99mTc-sestamibi thyroid uptake in euthyroid individuals and in patients with autoimmune thyroid disease. Eur J Nucl Med Mol Imaging 32: 702-707, 2005.
28. Stonnington HH, Engel AG: Normal and denervated muscle. Amorphometric study of fine structure. Neurology 23: 714-724, 1973
29. Van Ekeran GJ, Sengers RCA, Stadhouders AM: Changes in volume densities and distribution of mitochondria in rat skeletal muscle after chronic hypoxia. Int J Exp Path 73: 51-60, 1992.