HIV-1 superinfection in the antiretroviral therapy era: Are seroconcordant sexual partners at risk?

PLoS ONE

Volumn 4, Issue 5, 2009, Pages

  Campbell, Mary S ^a   Gottlieb, Geoffrey S ^a   Hawes, Stephen E ^c   Nickle, David C ^d   Wong, Kim G ^b   Deng, Wenjie ^b   Lampinen, Thomas M ^e   Kiviat, Nancy B ^a   Mullins, James I ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT;

ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; FEMALE; GENE SEQUENCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INFECTION RISK; LONGITUDINAL STUDY; MALE; NONHUMAN; PHYLOGENY; POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SEXUAL BEHAVIOR; SEXUALITY; SEXUALLY TRANSMITTED DISEASE; SUPERINFECTION; UNSAFE SEX; VIRUS DETECTION; VIRUS GENOME; VIRUS ISOLATION; VIRUS LOAD; VIRUS RECOMBINATION; VIRUS STRAIN; VIRUS TRANSMISSION; BLOOD; DEMOGRAPHY; DISEASE TRANSMISSION; DNA SEQUENCE; GENETIC RECOMBINATION; GENETICS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOMOSEXUALITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MONONUCLEAR CELL; MUCOSA; PHYSIOLOGY; RISK FACTOR; SEQUENCE ALIGNMENT; SPECIES DIFFERENCE; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; DEMOGRAPHY; HIV INFECTIONS; HIV-1; HOMOSEXUALITY, MALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MUCOUS MEMBRANE; PHYLOGENY; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; RISK FACTORS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEXUAL BEHAVIOR; SEXUAL PARTNERS; SPECIES SPECIFICITY; SUPERINFECTION;

EID: 66549115659     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005690     Document Type: Article

References (50)

1. Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, et al. (2003) Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS 17: F11-16.
2. Chohan B, Lavreys L, Rainwater SM, Overbaugh J (2005) Evidence for frequent reinfection with human immunodeficiency virus type 1 of a different subtype. J Virol 79: 10701-10708.
3. Ramos A, Hu DJ, Nguyen L, Phan KO, Vanichseni S, et al. (2002) Intersubtype Human Immunodeficiency Virus Type 1 Superinfection following Seroconversion to Primary Infection in Two Injection Drug Users. J Virol 76: 7444-7452.
4. Jost S, Bernard MC, Kaiser L, Yerly S, Hirschel B, et al. (2002) A patient with HIV-1 superinfection. N Engl J Med 347: 731-736.
5. Fang G, Weiser B, Kuiken C, Philpott SM, Rowland-Jones S, et al. (2004) Recombination following superinfection by HIV-1. AIDS 18: 153-159.
6. Yerly S, Jost S, Monnat M, Telenti A, Cavassini M, et al. (2004) HIV-1 co/super-infection in intravenous drug users. AIDS 18: 1413-1421.
7. Manigart O, Courgnaud V, Sanou O, Valea D, Nagot N, et al. (2004) HIV-1 superinfections in a cohort of commercial sex workers in Burkina Faso as assessed by an autologous heteroduplex mobility procedure. AIDS 18: 1645-1651.
8. Plantier JC, Lemee V, Dorval I, Gueudin M, Braun J, et al. (2004) HIV-1 group M superinfection in an HIV-1 group O-infected patient. AIDS 18: 2444-2446.
9. Brenner B, Routy JP, Quan Y, Moisi D, Oliveira M, et al. (2004) Persistence of multidrug-resistant HIV-1 in primary infection leading to superinfection. AIDS 18: 1653-1660.
10. Gottlieb GS, Nickle DC, Jensen MA, Wong KG, Grobler J, et al. (2004) Dual HIV-1 infection associated with rapid disease progression. Lancet 363: 619-622.
11. Chakraborty B, Kiser P, Rangel HR, Weber J, Mirza M, et al. (2004) Can HIV-1 superinfection compromise antiretroviral therapy? AIDS 18: 132-134.
12. Artenstein AW, VanCott TC, Mascola JR, Carr JK, Hegerich PA, et al. (1995) Dual infection with human immunodeficiency virus type 1 of distinct envelope subtypes in humans. J Infect Dis 171: 805-810.
13. Becker-Pergola G, Mellquist JL, Guay L, Mmiro F, Ndugwa C, et al. (2000) Identification of diverse HIV type 1 subtypes and dual HIV type 1 infection in pregnant Ugandan women. AIDS Res Hum Retroviruses 16: 1099-1104.
14. Diaz RS, Sabino EC, Mayer A, Mosley JW, Busch MP (1995) Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. The Transfusion Safety Study Group. J Virol 69: 3272-3281.
15. van der Kuyl AC, Kozaczynska K, van den Burg R, Zorgdrager F, Back N, et al. (2005) Triple HIV-1 infection. N Engl J Med 352: 2557-2559.
16. Gerhardt M, Mloka D, Tovanabutra S, Sanders-Buell E, Hoffmann O, et al. (2005) In-depth, longitudinal analysis of viral quasispecies from an individual triply infected with late-stage human immunodeficiency virus type 1, using a multiple PCR primer approach. J Virol 79: 8249-8261.
17. Altfeld M, Allen TM, Yu XG, Johnston MN, Agrawal D, et al. (2002) HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus. Nature 420: 434-439.
18. Janini LM, Tanuri A, Schechter M, Peralta JM, Vicente AC, et al. (1998) Horizontal and vertical transmission of human immunodeficiency virus type 1 dual infections caused by viruses of subtypes B and C. J Infect Dis 177: 227-231.
19. Grobler J, Gray CM, Rademeyer C, Seoighe C, Ramjee G, et al. (2004) Incidence of HIV-1 Dual Infection and Its Association with Increased Viral Load Set Point in a Cohort of HIV-1 Subtype C-Infected Female Sex Workers. J Infect Dis 190: 1355-1359.
20. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, et al. (2004) Incidence of HIV superinfection following primary infection. JAMA 292: 1177-1178.
21. Piantadosi A, Chohan B, Chohan V, McClelland RS, Overbaugh J (2007) Chronic HIV-1 infection frequently fails to protect against superinfection. PLoS Pathog 3: e177.
22. Herbinger KH, Gerhardt M, Piyasirisilp S, Mloka D, Arroyo MA, et al. (2006) Frequency of HIV type 1 dual infection and HIV diversity: analysis of low- and high-risk populations in Mbeya Region, Tanzania. AIDS Res Hum Retroviruses 22: 599-606.
23. Piantadosi A, Ngayo MO, Chohan B, Overbaugh J (2008) Examination of a Second Region of the HIV Type 1 Genome Reveals Additional Cases of Superinfection. AIDS Res Hum Retroviruses.
24. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, et al. (2005) HIV drug resistance acquired through superinfection. AIDS 19: 1251-1256.
25. Pernas M, Casado C, Fuentes R, Perez-Elias MJ, Lopez-Galindez C (2006) A dual superinfection and recombination within HIV-1 subtype B 12 years after primoinfection. J Acquir Immune Defic Syndr 42: 12-18.
26. Gottlieb GS, Nickle DC, Jensen MA, Wong KG, Kaslow RA, et al. (2007) HIV type 1 superinfection with a dual-tropic virus and rapid progression to AIDS: a case report. Clin Infect Dis 45: 501-509.
27. Rousseau CM, Learn GH, Bhattacharya T, Nickle DC, Heckerman D, et al. (2007) Extensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections. J Virol 81: 4492-4500.
28. Kozaczynska K, Cornelissen M, Reiss P, Zorgdrager F, van der Kuyl AC (2007) HIV-1 sequence evolution in vivo after superinfection with three viral strains. Retrovirology 4: 59.
29. Streeck H, Li B, Poon AF, Schneidewind A, Gladden AD, et al. (2008) Immune-driven recombination and loss of control after HIV superinfection. J Exp Med 205: 1789-1796.
30. Lampinen TM, Critchlow CW, Kuypers JM, Hurt CS, Nelson PJ, et al. (2000) Association of antiretroviral therapy with detection of HIV-1 RNA and DNA in the anorectal mucosa of homosexual men. AIDS 14: F69-75.
31. Liu SL, Schacker T, Musey L, Shriner D, McElrath MJ, et al. (1997) Divergent patterns of progression to AIDS after infection from the same source: human immunodeficiency virus type 1 evolution and antiviral responses. J Virol 71: 4284-4295.
32. Liu S-L, Rodrigo AG, Shankarappa R, Learn GH, Hsu L, et al. (1996) HIV quasispecies and resampling. Science 273: 415-416.
33. Shankarappa R, Margolick JB, Gange SJ, Rodrigo AG, Upchurch D, et al. (1999) Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection. J Virol 73: 10489-10502.
34. Rodrigo AG, Goracke PC, Rowhanian K, Mullins JI (1997) Quantitation of target molecules from polymerase chain reaction-based limiting dilution assays. AIDS Res and Hum Retrovir 13: 737-742.
35. Learn GH Jr, Korber BT, Foley B, Hahn BH, Wolinsky SM, et al. (1996) Maintaining the integrity of human immunodeficiency virus sequence databases. J Virol 70: 5720-5730.
36. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
37. Maddison WP, Maddison DR (2001) MacClade - Analysis of Phylogeny and Character Evolution - Version 4. Sunderland, MA: Sinauer Associates, Inc. pp 503.
38. Swofford DL (1999) PAUP* 4.0: Phylogenetic Analysis Using Parsimony (*and Other Methods). 4.0b2a ed. Sunderland, MA: Sinauer Associates, Inc.
39. Gottlieb GS, Heath L, Nickle DC, Wong KG, Leach SE, et al. (2008) HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study. J Infect Dis 197: 1011-1015.
40. Anderson JP, Learn GH, Rodrigo AG, He X, Wang Y, et al. (2003) Predicting demographic group structures based on DNA sequence data. Mol Biol Evol 20: 1168-1180.
41. Gonzales MJ, Delwart E, Rhee SY, Tsui R, Zolopa AR, et al. (2003) Lack of detectable human immunodeficiency virus type 1 superinfection during 1072 person-years of observation. J Infect Dis 188: 397-405.
42. Tsui R, Herring BL, Barbour JD, Grant RM, Bacchetti P, et al. (2004) Human immunodeficiency virus type 1 superinfection was not detected following 215 years of injection drug user exposure. J Virol 78: 94-103.
43. Willberg CB, McConnell JJ, Eriksson EM, Bragg LA, York VA, et al. (2008) Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus. PLoS Pathog 4: e1000185.
44. Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, et al. (2006) Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology 355: 1-5.
45. Douek DC, Picker LJ, Koup RA (2003) T cell dynamics in HIV-1 infection. Annu Rev Immunol 21: 265-304.
46. Battegay M, Nuesch R, Hirschel B, Kaufmann GR (2006) Immunological recovery and antiretroviral therapy in HIV-1 infection. Lancet Infect Dis 6: 280-287.
47. Mills EJ, Nachega JB, Bangsberg DR, Singh S, Rachlis B, et al. (2006) Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators. PLoS Med 3: e438.
48. (2003) Incorporating HIV prevention into the medical care of persons living with HIV. Recommendations of CDC, the Health Resources and Services Administration, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep 52: 1-24.
49. Golden MR, Stekler J, Hughes JP, Wood RW (2008) HIV serosorting in men who have sex with men: is it safe? J Acquir Immune Defic Syndr 49: 212-218.
50. Vernazza P, Hirschel B, Bernasconi E, Flepp M (2008) Les personnes seropositives ne souffrant d'aucune autre MST et suivant un traitement antiretroviral efficace ne transmettent pas le VIH par voie sexuelle. Bulletin des medecins suisses 89: 165-169.