Periodic therapeutic plasma exchange in patients with moderate to severe chronic myasthenia gravis non-responsive to immunosuppressive agents: An eight year follow-Up

Therapeutic Apheresis and Dialysis

Volumn 13, Issue 3, 2009, Pages 174-178

  Triantafyllou, Nik I ^a   Grapsa, Eirini Ioannis ^b   Kararizou, Evangelia ^a   Psimenou, Erasmia ^a   Lagguranis, Antonios ^a   Dimopoulos, Athanasios ^a  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b ALEXANDRA HOSPITAL   (Greece)

Author keywords

Immunosuppressive therapy; Intravenous immunoglobulin; Myasthenia gravis; Periodic plasma exchange; Plasmapheresis; Therapeutic plasma exchange

Indexed keywords

AZATHIOPRINE; IMMUNOGLOBULIN; PREDNISOLONE; PYRIDOSTIGMINE;

ADULT; AGED; CHRONIC DISEASE; CLINICAL ARTICLE; CONFERENCE PAPER; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; MALE; MYASTHENIA GRAVIS; PLASMAPHERESIS; PRIORITY JOURNAL; RELAPSE; REMISSION; SAFETY; SYMPTOM; THYMECTOMY; TREATMENT RESPONSE; WEANING;

ADULT; AGED; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; MYASTHENIA GRAVIS; PLASMA EXCHANGE; PROSPECTIVE STUDIES; REMISSION INDUCTION; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; YOUNG ADULT;

EID: 66549113102     PISSN: 17449979     EISSN: 17449987     Source Type: Journal    
DOI: 10.1111/j.1744-9987.2009.00684.x     Document Type: Conference Paper

References (22)

1. Phillips LH, Torner JC, Anderson MS, Cox GM. The epidemiology of myasthenia gravis in central and western Virginia. Neurology 1992 42 : 1888 93.
2. Treves TA, Rocca WA, Meneghini F. Epidemiology of myasthenia gravis. In : Anderson DW, Schoenberg DG, eds. Neuroepidemiology: A tribute to Bruce Schoenberg. Boston : CRC Press, 1991 297.
3. Romi F, Gilhus NE, Aarli JA. Myasthenia gravis: clinical immunological and therapeutic advance. Acta Neurol Scand 2005 111 : 134 41.
4. Almon RR, Andrew CG, Appel SH. Serum globulin in myasthenia gravis: inhibition of alpha-bungarotoxin binding to acetylcholine receptors. Science 1974 186 : 55 7.
5. Hoch W, McConville J, Helms S, Newsom-Davis J, Melms A, Vincent A. Auto-antibodies to the receptor tyrosine kinase Musk in patients with myasthenia gravis without AchR antibodies. Nat Med 2001 7 : 365 8.
6. Liyanage Y, Hoch W, Beeson D, Vincent A. The agrin / muscle-specific kinase pathway: new targets for autoimmune and genetic disorders at the neuromuscular junction. Muscle Nerve 2002 25 : 4 16. (Pubitemid 34019729)
7. Antozzi C, Gemma M, Regi B et al. A short plasma exchange protocol is effective in severe myasthenia gravis. J Neurol 1991 238 : 103 7.
8. Lavrnic D, Vujic A, Rakocevic-Stojanovic V et al. Cyclosporine in the treatment of myasthenia gravis. Acta Neurol Scand 2005 111 : 247 52.
9. Skeie GO, Apostolski S, Evoli A et al. Guidelines for the treatment of autoimmune neuromuscular trasmission disorders. Eur J Neurol 2006 13 : 691 9.
10. Szczepiorkowski ZM, Shaz BH, Bandarenko N, Winters JL. The new approach to assignment of ASFA Categories-introduction to the fourth special issue: clinical application of therapeutic apheresis. J Clin Apher 2007 22 : 96 105. (Pubitemid 47025119)
11. Kornfeld P, Ambinder EP, Mittag T et al. Plasmapheresis in refractory generalized myasthenia gravis. Arch Neurol 1981 38 : 478 81.
12. The use of therapeutic plasmapheresis for neurological disorders. National Institutes of Health Consensus Development Conference. Transfus Med Rev 1988 2 : 48 53.
13. Fornadi L, Horvath R, Szobor A. Myasthenia gravis: treatment with plasma exchange. Experience over 10 years. Acta Med Hung 1991 48 : 137 44.
14. Kornfeld P, Fox S, Maier K, Mahjoub M. Ten years experience with therapeutic apheresis in a community hospital. J Clin Apher 1992 7 : 63 8.
15. Tindall RSA, Rollins J. Apheresis in the treatment of myasthenia gravis. In : Valbonesi M, Pineda AA, Biggs JC, eds. Therapeutic Hemapheresis. Milan : Wichtig, 1986 43 52.
16. Gogovska L, Ljapcev R, Polenakovic M, Stojkovski L, Popovska M, Grcevska L. Plasmaexchange in the treatment of myasthenia gravis associated with thymoma. Int J Artif Organs 2003 26 : 170 3.
17. Batocchi AP, Evoli A, Di Schino C, Tonali P. Therapeutic apheresis in myasthenia gravis. Ther Apher 2000 4 : 275 9.
18. Newson-Davis J, Vincent A, Wilson SG, Ward CD. Long-term effects of repeated plasma exchange in myasthenia gravis. Lancet 1979 1 : 464 8.
19. Milner-Brown HS, Miller RG. Time course of improved neuromuscular function following plasma exchange alone and plasma exchange with prednisone/azathioprine in myasthenia gravis. J Neurol Sci 1982 57 : 357 68.
20. Rodnitzky RL, Bosch EP. Chronic long-interval plasma exchange in myasthenia gravis. Arch Neurol 1984 41 : 715 7.
21. Dau PC. Response to plasmapheresis and immunosuppressive drug therapy in sixty myasthenia gravis patients. Ann N Y Acad Sci 1981 377 : 700 8.
22. Chiu HC, Chen WH, Yeh JH. The six year experience of plasmapheresis in patients with myasthenia gravis. Ther Apher 2000 4 : 291 5.