Identification of interleukin-1, tumor necrosis factor-α, and interleukin-6 expression in lungs from pigs naturally infected with Mycoplasma hyopneumoniae by in situ hybridization

Journal of Veterinary Medical Science

Volumn 71, Issue 4, 2009, Pages 441-445

  Ahn, Kyoung Kyu ^a   Kwon, Donghyeok ^a   Jung, Kwonil ^a   Ha, Yooncheol ^a   Seo, Man Jun ^b   Kim, Sung Hoon ^b   Kim, Mi Young ^c   Cho, Kyung Dong ^c   Lee, Bog Hieu ^c   Chae, Chanhee ^a  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Chung Ang University   (South Korea)

Author keywords

Interleukin 1; Interleukin 6; Mycoplasma hyopneumoniae; Swine; Tumor necrosis factor

Indexed keywords

MYCOPLASMA HYOPNEUMONIAE; SUIDAE;

INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOSYNTHESIS; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IN SITU HYBRIDIZATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; MYCOPLASMA HYOPNEUMONIAE; MYCOPLASMAL PNEUMONIA OF SWINE; SWINE;

ANIMALS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERLEUKIN-1; INTERLEUKIN-6; MYCOPLASMA HYOPNEUMONIAE; PNEUMONIA OF SWINE, MYCOPLASMAL; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 66549093620     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.71.441     Document Type: Article

References (22)

1. Asai, T., Okada, M., Ono, M., Irisawa, T., Mori, Y., Yokomizo, Y. and Sato, S. 1993. Increased levels of tumor necrosis factor and interleukin 1 in bronchoalveolar lavage fluids from pigs infected with Mycoplasma hyopneumoniae. Vet. Immunol. Immunopathol. 38: 253-260.
2. Asai, T., Okada, M., Ono, M., Mori, Y., Yokomizo, Y. and Sato, S. 1994. Detection of interleukin-6 prostaglandin E2 in bronchoalveolar lavage fluids of pigs experimentally infected with Mycoplasma hyopneumoniae. Vet. Immunol. Immunopathol. 44: 97-102.
3. Beutler, B. and Cerami, A. 1989. The biology of cachectin/TNF, a primary mediator of the host response. Annu. Rev. Immunol. 7: 625-655.
4. Blanchard, B., Vena, M. M., Cavalier, A., Lannic, J. L., Gouranton, J. and Kobisch, M. 1992. Electron microscopic observation of the respiratory tract of SPF piglets inoculated with Mycoplasma hyopneumoniae. Vet. Microbiol. 30: 329-341.
5. Boehm, K. D., Yun, J. K., Strohl, K. P. and Elmets, C. A. 1995. Messenger RNAs for the multifunctional cytokines interleukin-1α, interleukin-1β and tumor necrosis factor-α are present in adnexal tissues and in dermis of normal human skin. Exp. Dermatol. 4: 335-341.
6. Cheon, D.-S., Chae, C. and Lee, Y.-S. 1997. Detection of nucleic acids of porcine reproductive and respiratory syndrome virus in the lungs of naturally infected piglets as determined by in-situ hybridization. J. Comp. Pathol. 117: 157-163.
7. Choi, C., Kwon, D., Min, K. and Chae, C. 1999. In-situ hybridization for the detection of inflammatory cytokines (IL-1, TNF-α and IL-6) in pigs naturally infected with Actinobacillus pleuropneumoniae. J. Comp. Pathol. 121: 349-356.
8. Dungworth, D. L. 1993. The respiratory system. pp. 661-663. In: Pathology of Domestic Animals vol. 2, 4th ed. (Jubb, K. F. C., Kennedy. P. C. and Palmer, N. eds.), Academic Press, New York.
9. Faulkner, C. B., Simecka, J. W., Davidson, M. K., Davis, J. K., Shoeb, T. R., Russell Lindsey, J. and Everson, M. P. 1995. Gene expression and production of tumor necrosis factor alpha, interleukin 1, interleukin 6, and gamma interferon in C3H/HeN and C57BL/6N mice in acute Mycoplasma pulmonis disease. Infect. Immun. 63: 4084-4090.
10. Kostyal, D. A., Butler, G. H. and Beezhold, D. H. 1995. Mycoplasma hyorhinis molecules that induce tumor necrosis factor alpha secretion by human monocytes. Infect. Immun. 63: 3858-3863.
11. Kwon, D. and Chae, C. 1999. Detection and localization of Mycoplasma hyopneumoniae DNA in lungs from naturally infected pigs by in situ hybridization using a digoxigeninlabeled probe. Vet. Pathol. 36: 308-313.
12. Lunney, J. K. 1993. Characterization of swine leukocyte differentiation antigens. Immunol. Today 14: 147-148.
13. Maes, D., Verdonck, M., Deluyker, H. and de Kruif, A. 1996. Enzootic pneumonia in pigs. Vet. Q. 18: 104-109.
14. Mebus, C. A. and Underdahl, N. R. 1977. Scanning electron microscopy of trachea and bronchi from gnotobiotic pigs inoculated with Mycoplasma hyopneumoniae. Am. J. Vet. Res. 38: 1249-1254.
15. Messier, S. and Ross, R. F. 1991. Interactions of Mycoplasma hyopneumoniae membranes with porcine lymphocytes. Am. J. Vet. Res. 52: 1497-1502.
16. Min, K. and Chae, C. 1998. Detection and distribution of DNA of Actinobacillus pleuropneumoniae in the lungs of naturally infected pigs by in-situ hybridzation. J. Comp. Pathol. 119: 169-175.
17. Nishimoto, M., Akashi, A., Kuwano, K., Tseng, C.-C., Ohizumi, K. and Arai, S. 1994. Gene expression of tumor necrosis factorα and interferon in the lungs of Mycoplasma pulmonisinfected mice. Microbiol. Immunol. 38: 345-352.
18. Ross, R. F. 1999. Mycoplasmal diseases. pp. 495-509. In: Diseases of Swine, 8th ed. (Straw, B. E., D'Allaire, S., Mengeling, W. L. and Taylor, D. J. eds.), Iowa State Press, Ames.
19. Van Snick, J. 1990. Interleukin-6: an overview. Annu. Rev. Immunol. 8: 253-278.
20. Vézina, S.-A., Roberge, D., Fournier, M., Dea S., Oth, D. and Archambault, D. 1995. Cloning of porcine cytokine-specific cDNAs and detection of porcine tumor necrosis factor alpha, interleukin-6 (IL-6), and IL-1β gene expression by reverse transcription PCR and chemiluminescence hybridization. Clin. Diagn. Lab. Immunol. 2: 665-671.
21. Zhao, Y.-X., Ljungdahl, A., Olsson, T. and Tarkowski, A. 1996. In situ hybridization analysis of synovial and systemic cytokine messenger RNA expression in superantigen-mediated Staphylococcus aureus arthritis. Arthritis Rheum. 39: 959-967
22. Zielinski, G, C. and Ross, R. F. 1993. Adherence of Mycoplasma hyopneumoniae to porcine ciliated respiratory tract cells. Am. J. Vet. Res. 54: 1262-1269.