Living donor kidney versus simultaneous pancreas-kidney transplant in type I diabetics: An analysis of the OPTN/UNOS database

Clinical Journal of the American Society of Nephrology

Volumn 4, Issue 4, 2009, Pages 845-852

  Young, Brian Y ^a   Gill, Jagbir ^a,b   Huang, Edmund ^c   Takemoto, Steven K ^d   Anastasi, Bishoy ^a   Shah, Tariq ^d   Bunnapradist, Suphamai ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d National Institute of Transplantation Los Angeles   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; ARTICLE; CONTROLLED STUDY; DATA BASE; FEMALE; FOLLOW UP; GRAFT RECIPIENT; GRAFT SURVIVAL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY GRAFT REJECTION; KIDNEY PANCREAS TRANSPLANTATION; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; MORTALITY; RISK ASSESSMENT; TREATMENT OUTCOME; ADOLESCENT; CHRONIC KIDNEY FAILURE; COMPARATIVE STUDY; DIABETIC NEPHROPATHY; DONOR SELECTION; HOSPITAL ADMISSION; MIDDLE AGED; PANCREAS TRANSPLANTATION; PATIENT SELECTION; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; STATISTICS; TIME; TRANSPLANTATION; UNITED STATES;

ADOLESCENT; ADULT; DATABASES AS TOPIC; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; DONOR SELECTION; FEMALE; GRAFT SURVIVAL; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; PANCREAS TRANSPLANTATION; PATIENT SELECTION; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; TIME FACTORS; TISSUE AND ORGAN PROCUREMENT; TREATMENT OUTCOME; UNITED STATES; WAITING LISTS; YOUNG ADULT;

EID: 66449134205     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.02250508     Document Type: Article

References (39)

1. Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY, Held PJ, Port FK: Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 341: 1725-1730, 1999
2. Meier-Kriesche HU, Ojo AO, Port FK, Arndorfer JA, Cibrik DM, Kaplan B: Survival improvement among patients with end-stage renal disease: trends over time for transplant recipients and wait-listed patients. J Am Soc Nephrol 12: 1293-1296, 2001
3. Oniscu GC, Brown H, Forsythe JL: Impact of cadaveric renal transplantation on survival in patients listed for transplantation. J Am Soc Nephrol 16: 1859-1865, 2005
4. United States Renal Data System: Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2007
5. Gaston RS, Basadonna G, Cosio FG, Davis CL, Kasiske BL, Larsen J, Leichtman AB, Delmonico FL: Transplantation in the diabetic patient with advanced chronic kidney disease: a task force report. Am J Kidney Dis 44: 529-542, 2004 (Pubitemid 39164629)
6. Becker BN, Brazy PC, Becker YT, Odorico JS, Pintar TJ, Collins BH, Pirsch JD, Leverson GE, Heisey DM, Sollinger HW: Simultaneous pancreas-kidney transplantation reduces excess mortality in type 1 diabetic patients with end-stage renal disease. Kidney Int 57: 2129-2135, 2000
7. Ojo AO, Meier-Kriesche HU, Hanson JA, Leichtman A, Magee JC, Cibrik D, Wolfe RA, Port FK, Agodoa L, Kaufman DB, Kaplan B: The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation 71: 82-90, 2001 (Pubitemid 32105783)
8. Bunnapradist S, Cho YW, Cecka JM, Wilkinson A, Danovitch GM: Kidney allograft and patient survival in type I diabetic recipients of cadaveric kidney alone versus simultaneous pancreas kidney transplants: A multivariate analysis of the UNOS database. J Am Soc Nephrol 14: 208-213, 2003 (Pubitemid 36026311)
9. Reddy KS, Stablein D, Taranto S, Stratta RJ, Johnston TD, Waid TH, McKeown JW, Lucas BA, Ranjan D: Long-term survival following simultaneous kidney-pancreas transplantation versus kidney transplantation alone in patients with type 1 diabetes mellitus and renal failure. Am J Kidney Dis 41: 464-470, 2003
10. Israni AK, Feldman HI, Propert KJ, Leonard M, Mange KC: Impact of simultaneous kidney-pancreas transplant and timing of transplant on kidney allograft survival. Am J Transplant 5: 374-382, 2005 (Pubitemid 40179525)
11. Rayhill SC, D'Alessandro AM, Odorico JS, Knechtle SJ, Pirsch JD, Heisey DM, Kirk AD, Van der Werf W, Sollinger HW: Simultaneous pancreas-kidney transplantation and living related donor renal transplantation in patients with diabetes: Is there a difference in survival? Ann Surg 231: 417-423, 2000
12. Becker BN, Rush SH, Dykstra DM, Becker YT, Port FK: Preemptive transplantation for patients with diabetes-related kidney disease. Arch Intern Med 166: 44-48, 2006 (Pubitemid 43063840)
13. 2006 Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1996-2005, Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation, Rockville, MD; United Network for Organ Sharing, Richmond, VA; University Renal Research and Education Association, Ann Arbor, MI, 2006
14. Cohen DJ, St Martin L, Christensen LL, Bloom RD, Sung RS: Kidney and pancreas transplantation in the United States, 1995-2004. Am J Transplant 6: 1153-1169, 2006
15. Ming CS, Chen ZH: Progress in pancreas transplantation and combined pancreas-kidney transplantation. Hepatobiliary Pancreat Dis Int 6: 17-23, 2007 (Pubitemid 46243154)
16. Meier-Kriesche HU, Li S, Gruessner RW, Fung JJ, Bustami RT, Barr ML, Leichtman AB: Immunosuppression: evolution in practice and trends, 1994-2004. Am J Transplant 6: 1111-1131, 2006
17. Gross CR, Limwattananon C, Matthees B, Zehrer JL, Savik K: Impact of transplantation on quality of life in patients with diabetes and renal dysfunction. Transplantation 70: 1736-1746, 2000 (Pubitemid 32064829)
18. Navarro X, Sutherland DE, Kennedy WR: Long-term effects of pancreatic transplantation on diabetic neuropathy. Ann Neurol 42: 727-736, 1997 (Pubitemid 27481545)
19. Fioretto P, Steffes MW, Sutherland DE, Goetz FC, Mauer M: Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med 339: 69-75, 1998 (Pubitemid 28304880)
20. Fioretto P, Sutherland DE, Najafian B, Mauer M: Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients. Kidney Int 69: 907-912, 2006 (Pubitemid 43297903)
21. Giannarelli R, Coppelli A, Sartini MS, Del Chiaro M, Vistoli F, Rizzo G, Barsotti M, Del Prato S, Mosca F, Boggi U, Marchetti P: Pancreas transplant alone has beneficial effects on retinopathy in type 1 diabetic patients. Diabetologia 49: 2977-2982, 2006 (Pubitemid 44730301)
22. Biesenbach G, Konigsrainer A, Gross C, Margreiter R: Progression of macrovascular diseases is reduced in type 1 diabetic patients after more than 5 years successful combined pancreas-kidney transplantation in comparison to kidney transplantation alone. Transpl Int 18: 1054-1060, 2005 (Pubitemid 41726774)
23. Orsenigo E, Socci C, Fiorina P, Zuber V, Secchi A, Di Carlo V, Staudacher C: Cardiovascular benefits of simultaneous pancreas-kidney transplant versus kidney alone transplant in diabetic patients. Transplant Proc 37: 3570-3571, 2005 (Pubitemid 41659956)
24. Takemoto SK, Cho YW and Gjertson DW: Transplant risks. Clin Transpl 325-334, 1999
25. Siddiqi N, McBride MA, Hariharan S: Similar risk profiles for post-transplant renal dysfunction and long-term graft failure: UNOS/OPTN database analysis. Kidney Int 65: 1906-1913, 2004
26. Giblin L, O'Kelly P, Little D, Hickey D, Donohue J, Walshe JJ, Spencer S, Conlon PJ: A comparison of long-term graft survival rates between the first and second donor kidney transplanted-the effect of a longer cold ischaemic time for the second kidney. Am J Transplant 5: 1071-1075, 2005 (Pubitemid 40571256)
27. Terasaki PI, Gjertson DW, Cecka JM, Takemoto S, Cho YW: Significance of the donor age effect on kidney transplants. Clin Transplant 11: 366-372, 1997 (Pubitemid 27460429)
28. Woo YM, McLean D, Kavanagh D, Ward L, Aitken S, Miller GJ, Egan P, Hughes K, Clark L, Carswell K, Morris ST, Northridge DB, Rodger RS, Jardine AG: The influence of pre-operative electrocardiographic abnormalities and cardiovascular risk factors on patient and graft survival following renal transplantation. J Nephrol 15: 380-386, 2002
29. Keith DS, Demattos A, Golconda M, Prather J, Norman D: Effect of donor recipient age match on survival after first deceased donor renal transplantation. J Am Soc Nephrol 15: 1086-1091, 2004 (Pubitemid 38375329)
30. Kauffman HM, McBride MA, Cors CS, Roza AM, Wynn JJ: Early mortality rates in older kidney recipients with comorbid risk factors. Transplantation 83: 404-410, 2007
31. Douzdjian V, Abecassis MM, Corry RJ, Hunsicker LG: Simultaneous pancreas-kidney versus kidney-alone transplants in diabetics: Increased risk of early cardiac death and acute rejection following pancreas transplants. Clin Transplant 8: 246-251, 1994 (Pubitemid 24162295)
32. Gruessner RW, Sutherland DE, Gruessner AC: Mortality assessment for pancreas transplants. Am J Transplant 4: 2018-2026, 2004
33. Gruessner RW, Dunn DL, Gruessner AC, Matas AJ, Najarian JS, Sutherland DE: Recipient risk factors have an impact on technical failure and patient and graft survival rates in bladder-drained pancreas transplants. Transplantation 57: 1598-1606, 1994
34. Becker BN, Odorico JS, Becker YT, Groshek M, Werwinski C, Pirsch JD, Sollinger HW: Simultaneous pancreas-kidney and pancreas transplantation. J Am Soc Nephrol 12: 2517-2527, 2001
35. Knoll GA, Nichol G: Dialysis, kidney transplantation, or pancreas transplantation for patients with diabetes mellitus and renal failure: A decision analysis of treatment options. J Am Soc Nephrol 14: 500-515, 2003 (Pubitemid 36150876)
36. Sureshkumar KK, Mubin T, Mikhael N, Kashif MA, Nghiem DD, Marcus RJ: Assessment of quality of life after simultaneous pancreas-kidney transplantation. Am J Kidney Dis 39: 1300-1306, 2002 (Pubitemid 34591949)
37. Sureshkumar KK, Patel BM, Markatos A, Nghiem DD, Marcus RJ: Quality of life after organ transplantation in type 1 diabetics with end-stage renal disease. Clin Transplant 20: 19-25, 2006 (Pubitemid 43349019)
38. Venstrom JM, McBride MA, Rother KI, Hirshberg B, Orchard TJ, Harlan DM: Survival after pancreas transplantation in patients with diabetes and preserved kidney function. JAMA 290: 2817-2823, 2003
39. Hariharan S, Pirsch JD, Lu CY, Chan L, Pesavento TE, Alexander S, Bumgardner GL, Baasadona G, Hricik DE, Pescovitz MD, Rubin NT, Stratta RJ: Pancreas after kidney transplantation. J Am Soc Nephrol 13: 1109-1118, 2002