메뉴 건너뛰기




Volumn 234, Issue 4, 2009, Pages 403-409

Mucosal immunization with polyamine transport protein D (PotD) protects mice against nasopharyngeal colonization with Streptococcus pneumoniae

Author keywords

PotD; Streptococcus pneumoniae; Vaccine

Indexed keywords

CHOLERA TOXIN B SUBUNIT; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PNEUMOCOCCUS VACCINE; POLYAMINE TRANSPORT PROTEIN D; UNCLASSIFIED DRUG;

EID: 66449128812     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0809-RM-269     Document Type: Article
Times cited : (31)

References (46)
  • 1
    • 0033618333 scopus 로고    scopus 로고
    • The burden of pneumococcal disease among adults in developed and developing countries: What is and is not known
    • PII S0264410X9900122X
    • Fedson DS, Scott JA. The burden of pneumococcal disease among adults in developed and developing countries: what is and is not known. Vaccine 17 Suppl 1:S11-18, 1999. (Pubitemid 29366927)
    • (1999) Vaccine , vol.17 , Issue.SUPPL. 1
    • Fedson, D.S.1    Anthony, J.2    Scott, G.3
  • 2
    • 0033546020 scopus 로고    scopus 로고
    • Pneumococcal vaccines. World Health Organization position paper
    • WHO
    • WHO. Pneumococcal vaccines. World Health Organization position paper. Wkly Epidemiol Rec 74:177-183, 1999.
    • (1999) Wkly Epidemiol Rec , vol.74 , pp. 177-183
  • 3
    • 0033618419 scopus 로고    scopus 로고
    • The clinical effectiveness of pneumococcal vaccination: A brief review
    • DOI 10.1016/S0264-410X(99)00113-9, PII S0264410X99001139
    • Fedson DS. The clinical effectiveness of pneumococcal vaccination: a brief review. Vaccine 17:S85-S90, 1999. (Pubitemid 29366941)
    • (1999) Vaccine , vol.17 , Issue.SUPPL. 1
    • Fedson, D.S.1
  • 4
    • 0033999821 scopus 로고    scopus 로고
    • Immunogenicity of pneumococcal conjugate vaccines
    • DOI 10.1097/00006454-200004000-00035
    • Eskola J. Immunogenicity of pneumococcal conjugate vaccines. Pediatr Infect Dis J 19:388-393, 2000. (Pubitemid 30213091)
    • (2000) Pediatric Infectious Disease Journal , vol.19 , Issue.4 , pp. 388-393
    • Eskola, J.1
  • 5
    • 39449083868 scopus 로고    scopus 로고
    • Emergence of nonvaccine serotypes following introduction of pneumococcal conjugate vaccine: Cause and effect?
    • Moore MR, Whitney CG. Emergence of nonvaccine serotypes following introduction of pneumococcal conjugate vaccine: cause and effect? Clin Infect Dis 46:183-185, 2008.
    • (2008) Clin Infect Dis , vol.46 , pp. 183-185
    • Moore, M.R.1    Whitney, C.G.2
  • 6
    • 0142029153 scopus 로고    scopus 로고
    • Novel vaccine strategies with protein antigens of Streptococcus pneumoniae
    • DOI 10.1016/S0928-8244(03)00146-9
    • Swiatlo E, Ware D. Novel vaccine strategies with protein antigens of Streptococcus pneumoniae. FEMS Immunol Med Microbiol 38:1-7, 2003. (Pubitemid 37297436)
    • (2003) FEMS Immunology and Medical Microbiology , vol.38 , Issue.1 , pp. 1-7
    • Swiatlo, E.1    Ware, D.2
  • 7
    • 0028028168 scopus 로고
    • Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae
    • Alexander JE, Lock RA, Peeters CCAM, Poolman JT, Andrew PW, Mitchell TJ, Hansman D, Paton JC. Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae. Infect Immun 62: 5683-5688, 1994. (Pubitemid 24365020)
    • (1994) Infection and Immunity , vol.62 , Issue.12 , pp. 5683-5688
    • Alexander, J.E.1    Lock, R.A.2    Peeters, C.C.A.M.3    Poolman, J.T.4    Andrew, P.W.5    Mitchell, T.J.6    Hansman, D.7    Paton, J.C.8
  • 8
    • 0036118026 scopus 로고    scopus 로고
    • Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae
    • Balachandran P, Brooks-Walter A, Virolainen-Julkunen A, Hollingshead SK, Briles DE. Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae. Infect Immun 70:2526-2534, 2002.
    • (2002) Infect Immun , vol.70 , pp. 2526-2534
    • Balachandran, P.1    Brooks-Walter, A.2    Virolainen-Julkunen, A.3    Hollingshead, S.K.4    Briles, D.E.5
  • 9
    • 0033984377 scopus 로고    scopus 로고
    • Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae
    • DOI 10.1128/IAI.68.2.796-800.2000
    • Briles DE, Ades E, Paton JC, Sampson JS, Carlone GM, Huebner RC, Virolainen A, Swiatlo E, Hollingshead SK. Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae. Infect Immun 68:796-800, 2000. (Pubitemid 30056538)
    • (2000) Infection and Immunity , vol.68 , Issue.2 , pp. 796-800
    • Briles, D.E.1    Ades, E.2    Paton, J.C.3    Sampson, J.S.4    Carlone, G.M.5    Huebner, R.C.6    Virolainen, A.7    Swiatlo, E.8    Hollingshead, S.K.9
  • 10
    • 0034778154 scopus 로고    scopus 로고
    • Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection
    • DOI 10.1128/IAI.69.11.6702-6706.2001
    • Brown JS, Ogunniyi AD, Woodrow MC, Holden DW, Paton JC. Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection. Infect Immun 69:6702-6706, 2001. (Pubitemid 32995427)
    • (2001) Infection and Immunity , vol.69 , Issue.11 , pp. 6702-6706
    • Brown, J.S.1    Ogunniyi, A.D.2    Woodrow, M.C.3    Holden, D.W.4    Paton, J.C.5
  • 11
    • 12844285741 scopus 로고    scopus 로고
    • PppA, a surface-exposed protein of Streptococcus pneumoniae, elicits cross-reactive antibodies that reduce colonization in a murine intranasal immunization and challenge model
    • DOI 10.1128/IAI.73.2.981-989.2005
    • Green BA, Zhang Y, Masi AW, Barniak V, Wetherell M, Smith RP, Reddy MS, Zhu D. PppA, a surface-exposed protein of Streptococcus pneumoniae, elicits cross-reactive antibodies that reduce colonization in a murine intranasal immunization and challenge model. Infect Immun 73:981-989, 2005. (Pubitemid 40165758)
    • (2005) Infection and Immunity , vol.73 , Issue.2 , pp. 981-989
    • Green, B.A.1    Zhang, Y.2    Masi, A.W.3    Barniak, V.4    Wetherell, M.5    Smith, R.P.6    Reddy, M.S.7    Zhu, D.8
  • 12
    • 33749253904 scopus 로고    scopus 로고
    • Immunization with Polyamine Transport Protein PotD protects mice against systemic infection with Streptococcus pneumoniae
    • DOI 10.1128/IAI.00553-06
    • Shah P, Swiatlo E. Immunization with polyamine transport protein PotD protects mice against systemic infection with Streptococcus pneumoniae. Infect Immun 74:5888-5892, 2006. (Pubitemid 44484576)
    • (2006) Infection and Immunity , vol.74 , Issue.10 , pp. 5888-5892
    • Shah, P.1    Swiatlo, E.2
  • 13
    • 0035007252 scopus 로고    scopus 로고
    • Recombinant PhpA protein, a unique histidine motif-containing protein from Streptococcus pneumoniae, protects mice against intranasal pneumococcal challenge
    • DOI 10.1128/IAI.69.6.3827-3836.2001
    • Zhang Y, Masi AW, Barniak V, Mountzouros K, Hostetter MK, Green BA. Recombinant PhpA protein, a unique histidine motif-containing protein from Streptococcus pneumoniae, protects mice against intranasal pneumococcal challenge. Infect Immun 69:3827-3836, 2001. (Pubitemid 32493302)
    • (2001) Infection and Immunity , vol.69 , Issue.6 , pp. 3827-3836
    • Zhang, Y.1    Masi, A.W.2    Barniak, V.3    Mountzouros, K.4    Hostetter, M.K.5    Green, B.A.6
  • 14
    • 46249115466 scopus 로고    scopus 로고
    • Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis
    • Glover DT, Hollingshead SK, Briles DE. Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis. Infect Immun 76(6):2767-2776, 2008.
    • (2008) Infect Immun , vol.76 , Issue.6 , pp. 2767-2776
    • Glover, D.T.1    Hollingshead, S.K.2    Briles, D.E.3
  • 15
    • 33845980590 scopus 로고    scopus 로고
    • Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae
    • DOI 10.1128/IAI.01103-06
    • Ogunniyi AD, Grabowicz M, Briles DE, Cook J, Paton JC. Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae. Infect Immun 75:350-357, 2007. (Pubitemid 46047911)
    • (2007) Infection and Immunity , vol.75 , Issue.1 , pp. 350-357
    • Ogunniyi, A.D.1    Grabowicz, M.2    Briles, D.E.3    Cook, J.4    Paton, J.C.5
  • 17
    • 0042665483 scopus 로고    scopus 로고
    • Immunizations with pneumococcal surface protein a and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae
    • DOI 10.1086/376571
    • Briles DE, Hollingshead SK, Paton JC, Ades EW, Novak L, van Ginkel FW, Benjamin WH Jr. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. J Infect Dis 188:339-348, 2003. (Pubitemid 36966099)
    • (2003) Journal of Infectious Diseases , vol.188 , Issue.3 , pp. 339-348
    • Briles, D.E.1    Hollingshead, S.K.2    Paton, J.C.3    Ades, E.W.4    Novak, L.5    Van Ginkel, F.W.6    Benjamin Jr., W.H.7
  • 18
    • 40549096043 scopus 로고    scopus 로고
    • A multifaceted role for polyamines in bacterial pathogens
    • Shah P, Swiatlo E. A multifaceted role for polyamines in bacterial pathogens. Molecular Microbiology 68:4-16, 2008.
    • (2008) Molecular Microbiology , vol.68 , pp. 4-16
    • Shah, P.1    Swiatlo, E.2
  • 19
    • 0033572636 scopus 로고    scopus 로고
    • Polyamine transport in bacteria and yeast
    • DOI 10.1042/0264-6021:3440633
    • Igarashi K, Kashiwagi K. Polyamine transport in bacteria and yeast. Biochem J 344 Pt 3:633-642, 1999. (Pubitemid 30032511)
    • (1999) Biochemical Journal , vol.344 , Issue.3 , pp. 633-642
    • Igarashi, K.1    Kashiwagi, K.2
  • 20
    • 27944435773 scopus 로고    scopus 로고
    • Utilization of putrescine by Streptococcus pneumoniae during growth in choline-limited medium
    • Ware D, Watt J, Swiatlo E. Utilization of putrescine by Streptococcus pneumoniae during growth in choline-limited medium. J Microbiol 43: 398-405, 2005. (Pubitemid 41666878)
    • (2005) Journal of Microbiology , vol.43 , Issue.5 , pp. 398-405
    • Ware, D.1    Watt, J.2    Swiatlo, E.3
  • 21
    • 33746570641 scopus 로고    scopus 로고
    • Cellular location of polyamine transport protein PotD in Streptococcus pneumoniae
    • DOI 10.1111/j.1574-6968.2006.00352.x
    • Shah P, Marquart M, Quin LR, Swiatlo E. Cellular location of polyamine transport protein PotD in Streptococcus pneumoniae. FEMS Microbiol Lett 261:235-237, 2006. (Pubitemid 44134158)
    • (2006) FEMS Microbiology Letters , vol.261 , Issue.2 , pp. 235-237
    • Shah, P.1    Marquart, M.2    Quin, L.R.3    Swiatlo, E.4
  • 23
    • 29644445164 scopus 로고    scopus 로고
    • Involvement of potD in Streptococcus pneumoniae polyamine transport and pathogenesis
    • DOI 10.1128/IAI.74.1.352-361.2006
    • Ware D, Jiang Y, Lin W, Swiatlo E. Involvement of potD in Streptococcus pneumoniae polyamine transport and pathogenesis. Infect Immun 74:352-361, 2006. (Pubitemid 43023091)
    • (2006) Infection and Immunity , vol.74 , Issue.1 , pp. 352-361
    • Ware, D.1    Jiang, Y.2    Lin, W.3    Swiatlo, E.4
  • 24
    • 48749108213 scopus 로고    scopus 로고
    • Role of polyamine transport in Streptococcus pneumoniae response to physiological stress and murine septicemia
    • Shah P, Romero DG, Swiatlo E. Role of polyamine transport in Streptococcus pneumoniae response to physiological stress and murine septicemia. Microb Pathog 45:167-172, 2008.
    • (2008) Microb Pathog , vol.45 , pp. 167-172
    • Shah, P.1    Romero, D.G.2    Swiatlo, E.3
  • 26
    • 0031239880 scopus 로고    scopus 로고
    • Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice
    • Wu H-Y, Virolainen A, Mathews B, King J, Russell MW, Briles DE. Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice. Microb Pathog 23:127-137, 1997.
    • (1997) Microb Pathog , vol.23 , pp. 127-137
    • Wu, H.-Y.1    Virolainen, A.2    Mathews, B.3    King, J.4    Russell, M.W.5    Briles, D.E.6
  • 29
    • 0026542944 scopus 로고
    • Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae
    • Briles DE, Crain MJ, Gray BM, Forman C, Yother J. Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae. Infect Immun 60:111-116, 1992.
    • (1992) Infect Immun , vol.60 , pp. 111-116
    • Briles, D.E.1    Crain, M.J.2    Gray, B.M.3    Forman, C.4    Yother, J.5
  • 30
    • 0042665483 scopus 로고    scopus 로고
    • Immunizations with pneumococcal surface protein a and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae
    • DOI 10.1086/376571
    • Briles DE, Hollingshead SK, Paton JC, Ades EW, Novak L, van Ginkel FW, Benjamin WH. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. J Infect Dis 188:339-348, 2003. (Pubitemid 36966099)
    • (2003) Journal of Infectious Diseases , vol.188 , Issue.3 , pp. 339-348
    • Briles, D.E.1    Hollingshead, S.K.2    Paton, J.C.3    Ades, E.W.4    Novak, L.5    Van Ginkel, F.W.6    Benjamin Jr., W.H.7
  • 31
    • 0026512896 scopus 로고
    • Pneumococcal proteins and the pathogenesis of disease caused by Streptococcus pneumoniae
    • Boulnois GJ. Pneumococcal proteins and the pathogenesis of disease caused by Streptococcus pneumoniae. J Gen Microbiol 138:249-259, 1992.
    • (1992) J Gen Microbiol , vol.138 , pp. 249-259
    • Boulnois, G.J.1
  • 32
    • 0026604355 scopus 로고
    • Infections caused by Streptococcus pneumoniae: Clinical spectrum, pathogenesis, immunity, and treatment
    • Musher DM. Infections caused by Streptococcus pneumoniae: clinical spectrum, pathogenesis, immunity, and treatment. Clin Infect Dis 14: 801-809, 1992.
    • (1992) Clin Infect Dis , vol.14 , pp. 801-809
    • Musher, D.M.1
  • 33
    • 0026554269 scopus 로고
    • Abundant attachment of bacteria to nasopharyngeal epithelium in otitis-prone children
    • Stenfors LE, Raisanen S. Abundant attachment of bacteria to nasopharyngeal epithelium in otitis-prone children. J Infect Dis 165: 1148-1150, 1992.
    • (1992) J Infect Dis , vol.165 , pp. 1148-1150
    • Stenfors, L.E.1    Raisanen, S.2
  • 34
    • 9244241532 scopus 로고    scopus 로고
    • ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies
    • DOI 10.1128/IAI.72.12.6757-6763.2004
    • Garmory HS, Titball RW. ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies. Infect Immun 72:6757-6763, 2004. (Pubitemid 39552342)
    • (2004) Infection and Immunity , vol.72 , Issue.12 , pp. 6757-6763
    • Garmory, H.S.1    Titball, R.W.2
  • 35
    • 25444456134 scopus 로고    scopus 로고
    • Antibodies to the iron uptake ABC transporter lipoproteins PiaA and PiuA promote opsonophagocytosis of Streptococcus pneumoniae
    • DOI 10.1128/IAI.73.10.6852-6859.2005
    • Jomaa M, Yuste J, Paton JC, Jones C, Dougan G, Brown JS. Antibodies to the iron uptake ABC transporter lipoproteins PiaA and PiuA promote opsonophagocytosis of Streptococcus pneumoniae. Infect Immun 73:6852-6859, 2005. (Pubitemid 41368853)
    • (2005) Infection and Immunity , vol.73 , Issue.10 , pp. 6852-6859
    • Jomaa, M.1    Yuste, J.2    Paton, J.C.3    Jones, C.4    Dougan, G.5    Brown, J.S.6
  • 36
    • 3042685720 scopus 로고    scopus 로고
    • The Ami-AliA/AliB permease of Streptococcus pneumoniae is involved in nasopharyngeal colonization but not in invasive disease
    • DOI 10.1128/IAI.72.7.3902-3906.2004
    • Kerr AR, Adrian PV, Estevao S, de Groot R, Alloing G, Claverys JP, Mitchell TJ, Hermans PW. The Ami-AliA/AliB permease of Streptococcus pneumoniae is involved in nasopharyngeal colonization but not in invasive disease. Infect Immun 72:3902-3906, 2004. (Pubitemid 38821904)
    • (2004) Infection and Immunity , vol.72 , Issue.7 , pp. 3902-3906
    • Kerr, A.R.1    Adrian, P.V.2    Estevao, S.3    De Groot, R.4    Alloing, G.5    Claverys, J.-P.6    Mitchell, T.J.7    Hermans, P.W.M.8
  • 37
    • 0036272450 scopus 로고    scopus 로고
    • Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae
    • DOI 10.1046/j.1365-2958.2002.02857.x
    • Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Mol Microbiol 45: 1389-1406, 2002. (Pubitemid 34595539)
    • (2002) Molecular Microbiology , vol.43 , Issue.6 , pp. 1471-1491
    • Merrell, D.S.1    Hava, D.L.2    Camilli, A.3
  • 40
    • 4644290141 scopus 로고    scopus 로고
    • Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization
    • DOI 10.1128/IAI.72.10.5807-5813.2004
    • McCool TL, Weiser JN. Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization. Infect Immun 72:5807-5813, 2004. (Pubitemid 39303692)
    • (2004) Infection and Immunity , vol.72 , Issue.10 , pp. 5807-5813
    • McCool, T.L.1    Weiser, J.N.2
  • 41
    • 27744437978 scopus 로고    scopus 로고
    • Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model
    • DOI 10.1128/IAI.73.11.7718-7726.2005
    • van Rossum AM, Lysenko ES, Weiser JN. Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model. Infect Immun 73:7718-7726, 2005. (Pubitemid 41587678)
    • (2005) Infection and Immunity , vol.73 , Issue.11 , pp. 7718-7726
    • Van Rossum, A.M.C.1    Lysenko, E.S.2    Weiser, J.N.3
  • 42
    • 33645521806 scopus 로고    scopus 로고
    • Antibody-independent, interleukin-17A-mediated, cross-serotype immunity to pneumococci in mice immunized intranasally with the cell wall polysaccharide
    • Malley R, Srivastava A, Lipsitch M, Thompson CM, Watkins C, Tzianabos A, Anderson PW. Antibody-independent, interleukin-17A-mediated, cross-serotype immunity to pneumococci in mice immunized intranasally with the cell wall polysaccharide. Infect Immun 74:2187-2195, 2006.
    • (2006) Infect Immun , vol.74 , pp. 2187-2195
    • Malley, R.1    Srivastava, A.2    Lipsitch, M.3    Thompson, C.M.4    Watkins, C.5    Tzianabos, A.6    Anderson, P.W.7
  • 43
    • 46249122178 scopus 로고    scopus 로고
    • Protection against nasopharyngeal colonization by Streptococcus pneumoniae is mediated by antigen-specific CD4+ T cells
    • Trzcinski K, Thompson CM, Srivastava A, Basset A, Malley R, Lipsitch M. Protection against nasopharyngeal colonization by Streptococcus pneumoniae is mediated by antigen-specific CD4+ T cells. Infect Immun 76(6):2678-2684, 2008.
    • (2008) Infect Immun , vol.76 , Issue.6 , pp. 2678-2684
    • Trzcinski, K.1    Thompson, C.M.2    Srivastava, A.3    Basset, A.4    Malley, R.5    Lipsitch, M.6
  • 44
    • 0034773167 scopus 로고    scopus 로고
    • Intranasal vaccination with pneumococcal surface protein a and Interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection
    • DOI 10.1128/IAI.69.11.6718-6724.2001
    • Arulanandam BP, Lynch JM, Briles DE, Hollingshead S, Metzger DW. Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection. Infect Immun 69:6718-6724, 2001. (Pubitemid 32995429)
    • (2001) Infection and Immunity , vol.69 , Issue.11 , pp. 6718-6724
    • Arulanandam, B.P.1    Lynch, J.M.2    Briles, D.E.3    Hollingshead, S.4    Metzger, D.W.5
  • 45
    • 33746632534 scopus 로고    scopus 로고
    • Intranasal immunization with the cholera toxin B subunit-pneumococcal surface antigen a fusion protein induces protection against colonization with Streptococcus pneumoniae and has negligible impact on the nasopharyngeal and oral microbiota of mice
    • DOI 10.1128/IAI.00134-06
    • Pimenta FC, Miyaji EN, Areas AP, Oliveira ML, de Andrade AL, Ho PL, Hollingshead SK, Leite LC. Intranasal immunization with the cholera toxin B subunit-pneumococcal surface antigen A fusion protein induces protection against colonization with Streptococcus pneumoniae and has negligible impact on the nasopharyngeal and oral microbiota of mice. Infect Immun 74:4939-4944, 2006. (Pubitemid 44157285)
    • (2006) Infection and Immunity , vol.74 , Issue.8 , pp. 4939-4944
    • Pimenta, F.C.1    Miyaji, E.N.2    Areas, A.P.M.3    Oliveira, M.L.S.4    De Andrade, A.L.S.S.5    Ho, P.L.6    Hollingshead, S.K.7    Leite, L.C.C.8
  • 46
    • 0030934988 scopus 로고    scopus 로고
    • Intranasal immunization of mice with PspA (Pneumococcal surface protein A) can prevent lntranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae
    • Wu HY, Nahm MH, Guo Y, Russell MW, Briles DE. Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae. J Infect Dis 175:839-846, 1997. (Pubitemid 27142957)
    • (1997) Journal of Infectious Diseases , vol.175 , Issue.4 , pp. 839-846
    • Wu, H.-Y.1    Nahm, M.H.2    Guo, Y.3    Russell, M.W.4    Briles, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.