A concise synthesis of indolic enamides: coscinamide A, coscinamide B, and igzamide

Tetrahedron Letters

Volumn 50, Issue 30, 2009, Pages 4343-4345

  Ma, Yuelong ^a   Yakushijin, Kenichi ^a   Miyake, Fumiko ^a   Horne, David ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Coscinamide A; Coscinamide B; Dehydration reaction; Igzamide; Indolic enamide

Indexed keywords

ANTINEOPLASTIC AGENT; COSCINAMIDE A; COSCINAMIDE B; IGZAMIDE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CARCINOMA CELL; CHEMICAL REACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; PROSTATE CARCINOMA;

EID: 66449125378     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.05.030     Document Type: Article

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16. +: 254.00548; found: 254.00486.
17. 6, 300 MHz) δ 182.3, 163.8, 139.1, 137.7, 136.7, 126.7, 125.4, 123.9, 123.8, 123.0, 121.7 × 2, 121.5, 117.7, 114.5, 114.3, 113.0, 112.6, 65.7, 46.2.
18. +: 329.1164; found: 329.1168.
19. +: 407.0269; found: 407.0273.
20. +: 340.0059; found: 340.0044.
21. +: 321.9953; found: 321.9960.
22. +: 306.9956; found: 306.9944.