Granulocytosis and thrombocytosis in renal cell carcinoma: A pro-inflammatory cytokine response originating in the tumour

Netherlands Journal of Medicine

Volumn 67, Issue 5, 2009, Pages 191-194

  Van Rossum, A P ^a   Vlasveld, L Th ^a   Vlasveld, I N ^b   Jansen, P M ^c   Dik, W A ^d   Hooijkaas, H ^d   Castel, A ^a  

^a MEDICAL CENTER HAAGLANDEN   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Cytokines; Inflammation; Interleukin 1; Interleukin 6; Renal cell carcinoma; Trombocytosis

Indexed keywords

C REACTIVE PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 8; THROMBOPOIETIN;

AGED; ARTICLE; CASE REPORT; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL FEATURE; CYTOKINE PRODUCTION; DISEASE COURSE; DISTANT METASTASIS; FEMALE; FEVER; GRANULOCYTOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KIDNEY CARCINOMA; KIDNEY VEIN; LYMPH NODE METASTASIS; MORTALITY; NEPHRECTOMY; RADIODIAGNOSIS; RENAL ARTERY; SUPERNATANT; THROMBOCYTOSIS; TUMOR CELL; TUMOR VOLUME; WEIGHT REDUCTION;

AGED; CARCINOMA, RENAL CELL; CYTOKINES; FATAL OUTCOME; FEMALE; GRANULOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKINS; KIDNEY NEOPLASMS; LEUKOCYTOSIS; THROMBOCYTOSIS;

EID: 66449121712     PISSN: 03002977     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Palapattu GS, Kristo B, Rajfer J. Paraneoplastic syndromes in urologic malignancy: the many faces of renal cell carcinoma. Rev Urol. 2002;4(4):163-170
2. Kan M, Tamura M, Kojima K, Naruo S, Kanayama H, Kagawa S. A case of renal cell carcinoma producing granulocyte-macrophage colony-stimulating factor. J Urol. 1996;155(6):2022-2023 (Pubitemid 126425663)
3. Suzuki A, Takahashi T, Nakamura K, et al. Thrombocytosis in patients with tumors producing colony-stimulating factor. Blood. 1992;80(8):2052-2059
4. Wang YC, Yang S, Tzen CY, Lin CC, Lin J. Renal cell carcinoma producing granulocyte colony-stimulating factor. J Formos Med Assoc. 2006;105(5):414-417
5. Blay JY, Rossi JF, Wijdenes J, et al. Role of interleukin-6 in the paraneoplastic inflammatory syndrome associated with renal-cell carcinoma. Int J Cancer. 1997;72(3):424-430 (Pubitemid 27325869)
6. Koo AS, Armstrong C, Bochner B, et al. Interleukin-6 and renal cell cancer: production, regulation, and growth effects. Cancer Immunol Immunother. 1992;35:97-105.
7. Brauner A, Soderhall M, Jacobson SH, Lundahl J, Andersson U, Andersson J. Escherichia coli-induced expression of IL-1 alpha, IL-1 beta, IL-6 and IL-8 in normal human renal tubular epithelial cells. Clin Exp Immunol. 2001;124(3):423-428 (Pubitemid 32701703)
8. Takenawa J, Kaneko Y, Fukumoto M, et al. Enhanced expression of interleukin-6 in primary human renal cell carcinomas. J Natl Cancer Inst. 1991;83:1668-1672
9. Sievers E, Dreimuller P, Haferkamp A, et al. Characterization of primary renal carnimoma cultures. Urol Int. 2007;79:235-243 (Pubitemid 47586932)
10. Ljungberg B, Grankvist K, Rasmuson T. Serum interleukin-6 in relation to acute-phase reactants and survival in patients with renal cell carcinoma. Eur J Cancer. 1997;33:1794-1798 (Pubitemid 28129206)
11. Dosquet C, Schaetz A, Faucher C et al. Tumour necrosis factor-alpha, interleukin-1 beta and interleukin-6 in patients with renal cell carcinoma. Eur J Cancer. 1994;30A:162-167 (Pubitemid 2050250)
12. Négrier S, Escudier B, Gomez F, et al. Prognostic factors of survival and rapid progression in 782 patients with metastatic renal carcinomas treated by cytokines: a report from the Groupe Français d'Immunothérapie. Ann Oncol. 2002;13:1460-1468
13. Guida M, Casamassima A, Monticelli G, Quaranta M, Colucci G. Basal cytokines profile in metastatic renal cell carcinoma patients treated with subcutaneous IL-2-based therapy compared with that of healthy donors. J Translational Med. 2007;5:51-57
14. Angelo LS, Talpaz M, Kurzrock R. Autocrine interleukin-6 production in renal cell carcinoma: evidence for the involvement of p53. Cancer Res. 2002;62:932-940 (Pubitemid 34126975)
15. Meloni-Ehrig AM. Renal cancer: cytogenetic and molecular genetic aspects. Semin Med Genet. 2002;115:164-172 (Pubitemid 35265506)
16. Cohen RJ, McNeal JE, Susman M, et al. Sarcomatoid renal cell carcinoma of papillary origin: a case report and cytogenetic evaluation. Arch Pathol Lab Med. 2000;124:1830-1832
17. Steiner T, Junker U, Wunderlich H, Schubert J. Are renal cell carcinoma cells able to modulate the cytotoxic effect of tumor infiltrating lymphocytes by secretion of interleukin-6? Anticancer Res. 1999;19(2C):1533-1536
18. Alstaedt J, Kirchner H, Rink L. Cytokine production of neutrophils is limited to interleukin 8. Immunology. 1996;89:563-568 (Pubitemid 26419658)
19. Vlasveld LT, Ermens AA. Inverse relation between plasma G-CSF levels and neutrophil counts in a patient with autoimmune neutropenia treated with G-CSF. Clin Lab Haematol. 2000;22:119-120 (Pubitemid 30331288)