Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort

Cerebrovascular Diseases

Volumn 28, Issue 2, 2009, Pages 131-134

  Ruigrok, Ynte M ^a   Rinkel, Gabriel J E ^a   Wijmenga, Cisca ^b,c   Kasuya, Hidetoshi ^d   Tajima, Atsushi ^e   Takahashi, Tomoko ^e   Hata, Akira ^f   Inoue, Ituro ^e   Krischek, Boris ^g  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^e TOKAI UNIVERSITY   (Japan)

^f CHIBA UNIVERSITY   (Japan)

^g UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Collagen 4A1; Fibrillin 2; Intracranial aneurysm; Perlecan; Single nucleotide polymorphism; Versican

Indexed keywords

COLLAGEN TYPE 4; COLLAGEN TYPE 4A1; FIBRILLIN 2; PERLECAN; UNCLASSIFIED DRUG; VERSICAN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INTRACRANIAL ANEURYSM; JAPANESE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; COHORT STUDIES; COLLAGEN TYPE IV; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; INTRACRANIAL ANEURYSM; JAPAN; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; NETHERLANDS; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; RISK FACTORS; VERSICANS;

EID: 66449105904     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000223438     Document Type: Article

References (18)

1. Rinkel GJE, Djibuti M, Algra A, van Gijn J: Prevalence and risk of rupture of intracranial aneurysms. Stroke 1998;29:251-256.
2. van Gijn J, Kerr RS, Rinkel GJE: Subarachnoid haemorrhage. Lancet 2007;369:306-318.
3. Hop JW, Rinkel GJE, Algra A, van Gijn J: Case fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke 1997;28:660-664. (Pubitemid 27118394)
4. Feigin VL, Rinkel GJ, Lawes CM, Algra A, Bennett DA, van Gijn J, Anderson S: Risk factors for subarachnoid hemorrhage: an updated systematic review of epidemiological studies. Stroke 2005;36:2773-2780.
5. Krischek B, Tatagiba M: The influence of genetics on intracranial aneurysm formation and rupture: current knowledge and its possible impact on future treatment. Adv Tech Stand Neurosurg 2008;33:137-147.
6. Semmler A, Linnebank M, Krex D, Götz A, Moskau S, Ziegler A, Simon M: Polymorphisms of homocysteine metabolism are associated with intracranial aneurysms. Cerebrovasc Dis 2008;26:425-429.
7. Ruigrok YM, Rinkel GJ: Genetics of intracranial aneurysms. Stroke 2008;39:1049-1055.
8. Ruigrok YM, Rinkel GJ, van't Slot R, Wolfs M, Tang S, Wijmenga C: Evidence in favor of the contribution of genes involved in the maintenance of the extracellular matrix of the arterial wall to the development of intracranial aneurysms. Hum Mol Genet 2006;15:3361-3368.
9. Ruigrok YM, Rinkel GJ, Wijmenga C: The versican gene and the risk of intracranial aneurysms. Stroke 2006;37:2372-2374.
10. Sun H, Zhang D, Zhao J: Chondroitin sulfate proteoglycan 2 (CSPG2) gene polymorphisms rs173686 and rs251124 are not associated with intracranial aneurysms in Chinese Han nationality. Ups J Med Sci 2007;112:289-295.
11. Nahed BV, Seker A, Guclu B, Ozturk AK, Finberg K, Hawkins AA, DiLuna ML, State M, Lifton RP, Gunel M: Mapping a Mendelian form of intracranial aneurysm to 1p34.3-p36.13. Am J Hum Genet 2004;76:172-179. (Pubitemid 40023777)
12. Ruigrok YM, Wijmenga C, Rinkel GJ, van't Slot R, Baas F, Westerveld A, Ross YB: Genomewide linkage in a large Dutch family with intracranial aneurysms: replication of 2 loci for intracranial aneurysms to chromosome 1p36.11-p36.13 and Xp22.2-p22.32. Stroke 2008;39:1096-1102.
13. Onda H, Kasuya H, Yoneyama T, Takakura K, Hori T, Takeda J, Nakajima T, Inoue I: Genomewide-linkage and haplotype-association studies map intracranial aneurysm to chromosome 7q11. Am J Hum Genet 2001;69:804-819. (Pubitemid 32868525)
14. Davis GE, Senger DR: Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res 2005;97:1093-1107.
15. Wu YJ, La Pierre DP, Wu J, Yee AJ, Yang BB: The interaction of versican with its binding partners. Cell Res 2005;15:483-494. (Pubitemid 41653919)
16. Segev A, Nili N, Strauss BH: The role of perlecan in arterial injury and angiogenesis. Cardiovasc Res 2004;63:603-610. (Pubitemid 39078673)
17. Colhoun HM, McKeigue PM, Davey SG: Problems of reporting genetic associations with complex outcomes. Lancet 2003;361:865-872.
18. de Rooij NK, Linn FH, van der Plas JA, Algra A, Rinkel GJ: Incidence of subarachnoid haemorrhage: a systematic review with emphasis on region, age, gender and time trends. J Neurol Neurosurg Psychiatry 2007;78:1365-1372. (Pubitemid 350221419)