Analysis of binding parameters of HIV-1 integrase inhibitors: Correlates of drug inhibition and resistance

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 13, 2009, Pages 4806-4818

  Loizidou, Eriketi Z ^a   Zeinalipour Yazdi, Constantinos D ^a   Christofides, Tasos ^a   Kostrikis, Leondios G ^a  

^a UNIVERSITY OF CYPRUS   (Cyprus)

Author keywords

Autodock; Elvitegravir; HIV 1 integrase; Inhibitors; Raltegravir; Resistance

Indexed keywords

ELVITEGRAVIR; INTEGRASE INHIBITOR; NAPHTHYRIDINE DERIVATIVE; OCTANOL; QUINOLINE DERIVATIVE; RALTEGRAVIR; WATER;

ARTICLE; DRUG ACTIVITY; DRUG PROTEIN BINDING; ENERGY TRANSFER; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PARTITION COEFFICIENT;

DRUG RESISTANCE, VIRAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 66449105516     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.04.058     Document Type: Article

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