High-frequency ultrasound to grade disease progression in murine models of Duchenne muscular dystrophy

Journal of Ultrasound in Medicine

Volumn 28, Issue 6, 2009, Pages 707-716

  Ahmad, Nabeel ^a,b,c   Bygrave, Mike ^b   Chhem, Rethy ^c   Hoffman, Lisa ^a,b   Welch, Ian ^e   Grange, Robert ^d   Fenster, Aaron ^b,c,e   Hill, David ^a   Lee, Ting Yim ^a,b,c,e  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

^d VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Calcification; Disease progression; Duchenne muscular dystrophy; High frequency ultrasound

Indexed keywords

BIOMINERALIZATION; CALCIFICATION (BIOCHEMISTRY); DAMAGE DETECTION; NEUROMUSCULAR REHABILITATION; PROTEINS; ULTRASONICS;

ARCHITECTURAL CHANGES; CYTOSKELETAL PROTEINS; DISEASE PROGRESSION; DUCHENNE MUSCULAR DYSTROPHIES; HIGH FREQUENCY ULTRASOUNDS; LONGITUDINAL STUDY; MUSCLE ARCHITECTURES; SPATIAL RESOLUTION;

MUSCLE;

DYSTROPHIN; UTROPHIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DUCHENNE MUSCULAR DYSTROPHY; GENE MUTATION; MOUSE; MUSCLE INJURY; NONHUMAN; RATING SCALE; SCORING SYSTEM; ULTRASOUND;

EID: 66449091821     PISSN: 02784297     EISSN: None     Source Type: Journal    
DOI: 10.7863/jum.2009.28.6.707     Document Type: Article

References (28)

1. Hoffman EP, Brown RH Jr, Kunkel LM. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 1987; 51:919-928.
2. Blake DJ, Weir A, Newey SE, Davies KE. Function and genetics of dystrophin and dystrophin-related proteins in muscle. Physiol Rev 2002; 82:291-329.
3. Emery AE. The muscular dystrophies. Lancet 2002; 359: 687-695.
4. Bell CD, Conen PE. Histopathological changes in Duchenne muscular dystrophy. J Neurol Sci 1968; 7:529-544.
5. Bradley WG, Fulthorpe JJ. Studies of sarcolemmal integrity in myopathic muscle. Neurology 1978; 28:670-677.
6. Spencer MJ, Tidball JG. Do immune cells promote the pathology of dystrophin-deficient myopathies? Neuromuscul Disord 2001; 11:556-564.
7. Hess JW, MacDonald RP, Frederick RJ, Jones RN, Neely J, Gross D. Serum creatine phosphokinase (Cpk) activity in disorders of heart and skeletal muscle. Ann Intern Med 1962; 61:1015-1028.
8. Zuberi SM, Matta N, Nawaz S, Stephenson JB, McWilliam RC, Hollman A. Muscle ultrasound in the assessment of suspected neuromuscular disease in childhood. Neuromuscul Disord 1999; 9:203-207.
9. Maurits NM, Bollen AE, Windhausen A, De Jager AE, Van Der Hoeven JH. Muscle ultrasound analysis: normal values and differentiation between myopathies and neuropathies, Ultrasound Med Biol 2003; 29:215-225.
10. Scholten RR, Pillen, S, Verrips A, Zwarts MJ. Quantitative ultrasonography of skeletal muscles in children: normal values. Muscle Nerve 2003; 27:693-698.
11. Reimers K, Reimers CD, Wagner S, Paetzke I, Pongratz DE. Skeletal muscle sonography: a correlative study of echogenicity and morphology. J Ultrasound Med 1993; 12:73-77.
12. Pillen S, Verrips A, van Alfen N, Arts IM, Sie LT, Zwarts MJ. Quantitative skeletal muscle ultrasound: diagnostic value in childhood neuromuscular disease. Neuromuscul Disord 2007; 17:509-516.
13. Bianchi S, Martinoli C, Abdelwahab IF, Derchi LE, Damiani S. Sonographic evaluation of tears of the gastrocnemius medial head ("tennis leg"). J Ultrasound Med 1998; 17:157-162.
14. Bianchi S, Martinoli C. Ultrasound of the musculoskeletal system. In: Diagnostic Imaging. New York, Springer; 2006:50-60.
15. Meng C, Adler R, Peterson M, Kagen L. Combined use of power Doppler and gray-scale sonography: a new technique for the assessment of inflammatory myopathy. J Rheumatol 2001; 28:1271-1282.
16. Fenster A, Downey DB, Cardinal HN. Three-dimensional ultrasound imaging. Phys Med Biol 2001; 46:R67-R99.
17. Thompson S. Selected Histochemical and Histopathological Methods. Springfield, IL: Charles C Thomas; 1966.
18. Foster FS, Zhang MY, Zhou YQ, et al. A new ultrasound instrument for in vivo microimaging of mice. Ultrasound Med Biol 2002; 28:1165-1172.
19. Koh ES, McNally EG. Ultrasound of skeletal muscle injury. Semin Musculoskelet Radiol 2007; 11:162-173.
20. Gosselin LE, McCormick KM. Targeting the immune system to improve ventilatory function in muscular dystrophy. Med Sci Sports Exerc 2004; 36:44-51.
21. Holt PG. Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages. Clin Exp Immunol 1986; 63:261-270.
22. Alderton JM, Steinhardt RA. Calcium influx through calcium leak channels is responsible for the elevated levels of calcium-dependent proteolysis in dystrophic myotubes. J Biol Chem 2000; 275:9452-9460.
23. Ruegg UT, Gillis JM. Calcium homeostasis in dystrophic muscle. Trends Pharmacol Sci 1999; 20:351-362.
24. Petrof BJ. Molecular pathophysiology of myofiber injury in deficiencies of the dystrophin-glycoprotein complex. Am J Phys Med Rehabil 2002; 81(suppl):S162-S174.
25. Elsherif L, Huang MS, Shai SY, et al. Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification. Circ Res 2008; 102:1109-1117.
26. Tinsley J, Deconinck N, Fisher R, et al. Expression of full-length utrophin prevents muscular dystrophy in mdx mice. Nat Med 1998; 4:1441-1444.
27. Cullen MJ, Mastaglia FL. Pathological reactions of skeletal muscle. In: Mastaglia FL, Walton JN (eds). Skeletal Muscle Pathology. Edinburgh, Scotland: Churchill Livingstone; 1982:88-139.
28. Cullen MJ, Jaros E. Ultrastructure of the skeletal muscle in the X chromosome-linked dystrophic (mdx) mouse: comparison with Duchenne muscular dystrophy. Acta Neuropathol 1988; 77:69-81.