The Chronology of Age-Related Spatial Learning Impairment in Two Rat Strains, as Tested by the Barnes Maze

Behavioral Neuroscience

Volumn 123, Issue 3, 2009, Pages 533-538

  Barrett, Graham L ^a   Bennie, Antoinette ^a   Trieu, Jennifer ^a   Ping, Sophie ^a   Tsafoulis, Christine ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

aging; cognitive impairment; hippocampus; sex differences; spatial memory

Indexed keywords

AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONOLOGY; COGNITIVE DEFECT; CONTROLLED STUDY; DARK AGOUTI RAT; FEMALE; HIPPOCAMPUS; LEARNING DISORDER; MALE; MAZE TEST; NONHUMAN; RAT; RAT STRAIN; SEX DIFFERENCE; SPATIAL MEMORY; SPRAGUE DAWLEY RAT; STRAIN DIFFERENCE; TASK PERFORMANCE;

AGING; ANALYSIS OF VARIANCE; ANIMALS; FEMALE; LEARNING DISORDERS; MALE; MAZE LEARNING; NEUROPSYCHOLOGICAL TESTS; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SPACE PERCEPTION; SPECIES SPECIFICITY; TIME FACTORS;

EID: 66349134838     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0015063     Document Type: Article

References (27)

1. Bizon, J. L., Lasarge, C. L., Montgomery, K. S., McDermott, A. N., Setlow, B., & Griffith, W. H. (in press). Spatial reference and working memory across the lifespan of male Fischer 344 rats. Neurobiology of Aging
2. Canzian F. Phylogenetics of the laboratory rat Rattus norvegicus. Genome Research 7 (1997) 262-267
3. Clemens J.A., and Meites J. Neuroendocrine status of old constant-estrous rats. Neuroendocrinology 7 (1971) 249-256
4. Daniel J.M., Hulst J.L., and Berbling J.L. Estradiol replacement enhances working memory in middle-aged rats when initiated immediately after ovariectomy but not after a long-term period of ovarian hormone deprivation. Endocrinology 147 (2006) 607-614
5. Festing M.F., and Bender K. Genetic relationships between inbred strains of rats. An analysis based on genetic markers at 28 biochemical loci. Genetical Research 44 (1984) 271-281
6. Frick K.M., Baxter M.G., Markowska A.L., Olton D.S., and Price D.L. Age-related spatial reference and working memory deficits assessed in the water maze. Neurobiology of Aging 16 (1995) 149-160
7. Gallagher M., Burwell R., and Burchinal M. Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze. Behavioral Neuroscience 107 (1993) 618-626
8. Greferath U., Bennie A., Kourakis A., and Barrett G.L. Impaired spatial learning in aged rats is associated with loss of p75-positive neurons in the basal forebrain. Neuroscience 100 (2000) 363-373
9. Huang H.H., Steger R.W., Bruni J.F., and Meites J. Patterns of sex steroid and gonadotropin secretion in aging female rats. Endocrinology 103 (1978) 1855-1859
10. Kwitek A.E., Jacob H.J., Baker J.E., Dwinell M.R., Forster H.V., Greene A.S., et al. BN phenome: Detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiological Genomics 25 (2006) 303-313
11. Lindner M.D. Reliability, distribution, and validity of age-related cognitive deficits in the Morris water maze. Neurobiology of Learning and Memory 68 (1997) 203-220
12. Mabry T.R., Gold P.E., and McCarty R. Age-related changes in plasma catecholamine responses to acute swim stress. Neurobiology of Learning and Memory 63 (1995) 260-268
13. Markowska A.L. Sex dimorphisms in the rate of age-related decline in spatial memory: Relevance to alterations in the estrous cycle. Journal of Neuroscience 19 (1999) 8122-8133
14. Markowska A.L., and Savonenko A.V. Effectiveness of estrogen replacement in restoration of cognitive function after long-term estrogen withdrawal in aging rats. Journal of Neuroscience 22 (2002) 10985-10995
15. McLay R.N., Freeman S.M., Harlan R.E., Kastin A.J., and Zadina J.E. Tests used to assess the cognitive abilities of aged rats: Their relation to each other and to hippocampal morphology and neurotrophin expression. Gerontology 45 (1999) 143-155
16. McLay R.N., Freeman S.M., and Zadina J.E. Chronic corticosterone impairs memory performance in the Barnes maze. Physiology and Behavior 63 (1998) 933-937
17. Muir J.L., Fischer W., and Bjorklund A. Decline in visual attention and spatial memory in aged rats. Neurobiology of Aging 20 (1999) 605-615
18. Ping S.E., Greferath U., and Barrett G.L. Estrogen treatment suppresses forebrain p75 neurotrophin receptor expression in aged, noncycling female rats. Journal of Neuroscience Research 69 (2002) 51-60
19. Ping S.E., Trieu J., Wlodek M.E., and Barrett G.L. Effects of estrogen on basal forebrain cholinergic neurons and spatial learning. Journal of Neuroscience Research 86 (2008) 1588-1598
20. Smith T.D., Gallagher M., and Leslie F.M. Cholinergic binding sites in rat brain: Analysis by age and cognitive status. Neurobiology of Aging 16 (1995) 161-173
21. Smits B.M., van Zutphen B.F., Plasterk R.H., and Cuppen E. Genetic variation in coding regions between and within commonly used inbred rat strains. Genome Research 14 (2004) 1285-1290
22. Stemmelin J., Lazarus C., Cassel S., Kelche C., and Cassel J.C. Immunohistochemical and neurochemical correlates of learning deficits in aged rats. Neuroscience 96 (2000) 275-289
23. Sternberg E.M., Glowa J.R., Smith M.A., Calogero A.E., Listwak S.J., Aksentijevich S., et al. Corticotropin releasing hormone related behavioral and neuroendocrine responses to stress in Lewis and Fischer rats. Brain Research 570 (1992) 54-60
24. Thomas M.A., Chen C.F., Jensen-Seaman M.I., Tonellato P.J., and Twigger S.N. Phylogenetics of rat inbred strains. Mammalian Genome 14 (2003) 61-64
25. Veng L.M., Granholm A.C., and Rose G.M. Age-related sex differences in spatial learning and basal forebrain cholinergic neurons in F344 rats. Physiology and Behavior 80 (2003) 27-36
26. Walf A.A., and Frye C.A. Conjugated equine estrogen enhances rats' cognitive, anxiety, and social behavior. Neuroreport 19 (2008) 789-792
27. Wu J., Zhu Y., and Wu J. Effects of estrogen and estrogenic compounds on cognition in ovariectomized rats. Climacteric 11 (2008) 212-220