Cytocompatibility and hemocompatibility of a novel chitosan-alginate gel system

Journal of Biomedical Materials Research - Part A

Volumn 89, Issue 4, 2009, Pages 854-864

  Notara, M ^a,b   Scotchford, C A ^a   Grant, D M ^a   Weston, N ^a   Roberts, G A F ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Alginate; Chitosan; Cytocompatibility; Hemolysis; Platelet activation

Indexed keywords

ALGINATE GEL; BLOOD CONTACT; CELL VIABILITY; CHITOSAN-SODIUM ALGINATE BLEND; CYTOCOMPATIBILITY; GEL SYSTEMS; GEL-TYPE; GLUTARALDEHYDE; HEMOCOMPATIBILITY; HEMOLYSIS; METHYLSULFONIC ACID; MINIMAL EFFECTS; MOUSE-FIBROBLASTS; PLATELET ACTIVATION; WHOLE BLOOD;

ACIDS; ALDEHYDES; ALGINATE; AMMONIUM COMPOUNDS; BLENDING; BLOOD; BLOOD SUBSTITUTES; CALCIUM; CALCIUM CHLORIDE; CELL CULTURE; CELL MEMBRANES; CHITIN; CHITOSAN; GELATION; GELS; HYDROGELS; SODIUM;

PLATELETS;

ALGINIC ACID; BOVINE SERUM ALBUMIN; CALCIUM CHLORIDE; CHITOSAN; FIBRONECTIN; GLUTARALDEHYDE; SERUM ALBUMIN;

ANIMAL CELL; ARTICLE; BLOOD COMPATIBILITY; CELL GROWTH; CELL VIABILITY; CONTACT ANGLE; CONTROLLED STUDY; CYTOTOXICITY; ELUTION; FIBROBLAST; GEL; HEMOLYSIS; MEMBRANE FORMATION; MOUSE; NONHUMAN; THROMBOCYTE ACTIVATION;

3T3 CELLS; ADSORPTION; ALGINATES; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL PROLIFERATION; CELL SURVIVAL; CHITOSAN; FIBROBLASTS; FIBRONECTINS; GELS; GLUCURONIC ACID; HEMOGLOBINS; HEMOLYSIS; HEXURONIC ACIDS; MATERIALS TESTING; MEMBRANES, ARTIFICIAL; MICE; PLATELET ACTIVATION; PLATELET ADHESIVENESS; RABBITS; SERUM ALBUMIN, BOVINE; SURFACE PROPERTIES;

EID: 66249116671     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32027     Document Type: Article

References (27)

1. Richardson SCW, Kolbe HJV, Duncan R. Potential of low molecular mass chitosan as a DNA delivery system: Biocompatibility, body distribution and ability to complex and protect DNA. Int J Pharm 1999;178:231-243.
2. Koping-Hoggard M, Mel'nikova YS, Varum KM, Lindman B, Artursson P. Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo. J Gene Med 2003;5:130-141.
3. Hoemann CD, Sun J, McKee MD, Chevrier A, Rossomacha E, Rivard GE, Hurtig M, Buschmann MD. Chitosan-glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects. Osteoarthritis Cartilage 2007;15:78-89.
4. Hashimoto T, Suzuki Y, Tanihara M, Kakimaru Y, Suzuki K. Development of alginate wound dressings linked with hybrid peptides derived from laminin and elastin. Biomaterials 2004; 25:1407-1414.
5. Roberts G, Andrew F. Chitosan condensation products, their preparation and their uses. 2001. European patent: EP1250359.
6. Roberts G, Andrew F. A novel solvent system for chitosan. In: Struszczyk H, Domard A, Peter MG, Pospieszny H, editors. Advances in Chitin Science. Poznan: ESUS; 2004. p 430- 433
7. Gough JE, Scotchford CA, Dowries S. Cytotoxicity of glutaralde- hyde crosslinked collagen/poly(vinyl alcohol) films is by the mechanism of apoptosis. J Biomed Mater Res A 2002;61:121-130.
8. Grabenwoger MJ, Grimm M, Eybl E, Moritz A, Muller MM, Bock P, Wolner E. Endothelial-cell lining of bioprosthetic heart-valve material. J Cardiac Surg 1992;7:79-84.
9. Roberts GAF. A novel chitosan-based gel system. J Met Mat Min 2005;15:13-18.
10. Alarayyid NA, Graham BR, Ferdous AH, Betteridge DJ, Prichard BNC, Smith CCT. An examination of some factors which influence the stability of in-vitro platelet responses. Platelets 1994;5:317-324.
11. Goodman SL, Lelah MD, Lambrecht LK, Cooper SL, Albrecht RM. Invitro vs exvivo platelet deposition on polymer surfaces. Scan Elec Micr 1984:279-290.
12. Maitz MF, Pham MT, Wieser E. Blood compatibility of titanium oxides with various crystal structure and element doping. J Biomater Appl 2003;17:303-319.
13. Park JY, Gemmelll CH, Davies JE. Platelet interactions with titanium: Modulation of platelet activity by surface topography. Biomaterials 2001;22:2671-2682.
14. Shenkman B, Savion N, Dardik R, Tamarin I, Varon D. Testing of platelet deposition on polystyrene surface under flow conditions by the cone and plate(let) analyzer: Role of platelet activation, fibrinogen and von Willebrand factor. Thromb Res 2000;99:353-361.
15. Mao C, Qiu YZ, Sang HB, Mei H, Zhu AP, Shen J, Lin SC. Various approaches to modify biomaterial surfaces for improving hemocompatibility. Adv Colloid Interfac 2004;110:5-17.
16. Orban JM, Wilson LB, Kofroth JA, El-Kurdi MS, Maul TM, Vorp DA. Crosslinking of collagen gels by transglutaminase. J Biomed Mater Res A 2004;68:756-762.
17. Maizato MJS, Higa OZ, Mathor MB, Camillo MAP, Spencer PJ, Pitombo RN, Zavaglia CAC, Leirner AA. Glutaraldehyde- treated bovine pericardium: Effects of lyophilization on cytotoxicity and residual aldehydes. Artif Organs 2003;27:692- 694.
18. Gong HP, Zhong YH, Li JC, Gong YD, Zhao NM, Zhang XF. Studies on nerve cell affinity of chitosan-derived materials. J Biomed Mater Res A 2000;52:285-295.
19. Bumgardner JD, Wiser R, Elder SH, Jouett R, Yang Y, Ong JL. Contact angle, protein adsorption and osteoblast precursor cell attachment to chitosan coatings bonded to titanium. J Biomat Sci Polym E 2003;14:1401-1409.
20. Khor E. Chitin: A Biomaterials Promise. Amsterdam: Elsevier; 2001.
21. Jumaa M, Furkert FH, Muller BW. A new lipid emulsion formulation with high antimicrobial efficacy using chitosan. Eur J Pharm Biopharm 2002;53:115-123.
22. Lamberti FV, Sefton MV. Microencapsulation of erythrocytes in eudragit-rl-coated calcium alginate. Biochim Biophys Acta 1983;759:81-91.
23. Wiegand F, Kroncke KD, Kolbbachofen V. Macrophage-gener- ated nitric-oxide as cytotoxic factor in destruction of alginate-encapsulated islets - protection of arginine analogs and/or coen- capsulated erythrocytes. Transplantation 1993;56:1206-1212.
24. Offeman RD, Williams MC. Observations on shear-induced hemolysis. Biomat Med Dev Artif Org 1979;7:393-420.
25. Hoffbrand AV, Pettit JE, Moss PAH. Essential Haematology, 4th ed. Oxford: Blackwell Science; 2002.
26. Barbucci R, Magnani A, Lamponi S, Albanese A. Chemistry and biology of glycosaminoglycans in blood coagulation. Polym AdvTechnol 1996;7:675-685.
27. Noh H, Vogler EA. Volumetric interpretation of protein adsorption: Mass and energy balance for albumin adsorption to particulate adsorbents with incrementally increasing hydrophilicity. Biomaterials 2006;27:5801-5812.