Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests

Anaesthesia and Intensive Care

Volumn 37, Issue 3, 2009, Pages 477-480

  Chakravarty, C ^a   Singh, P M ^a   Trikha, A ^a   Arora, M K ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Cardiac arrest; Intravenous fluconazole; Prolonged QT; Torsades de pointes; Ventricular fibrillation

Indexed keywords

AMPHOTERICIN B; CIPROFLOXACIN; FLUCONAZOLE; IMIPENEM; INSULIN; LIDOCAINE; LOW MOLECULAR WEIGHT HEPARIN; METRONIDAZOLE; MIDAZOLAM; MORPHINE;

ADULT; ARTICLE; CANDIDIASIS; CASE REPORT; CLINICAL EXAMINATION; DEFIBRILLATION; DIABETIC KETOACIDOSIS; ELECTROCARDIOGRAPHY; FEMALE; HEART ARREST; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; HYPOCALCEMIA; HYPOKALEMIA; PHYSICAL EXAMINATION; RECURRENT DISEASE; TORSADE DES POINTES;

EID: 66249109613     PISSN: 0310057X     EISSN: None     Source Type: Journal    
DOI: 10.1177/0310057x0903700311     Document Type: Article

References (11)

1. Dorsey ST, Biblo LA. Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline. Am J Emerg Med 2000; 18:227-229. (Pubitemid 30163908)
2. Tholakanahalli VN, Potti A, Hanley JF, Merliss AD. Fluconazole-induced torsade de pointes. Ann Pharmacother 2001; 35:432-434. (Pubitemid 32260209)
3. Tatetsu H, Asou N, Nakamura M, Hanaoka N, Matsuno F, Horikawa K et al. Torsades de pointes upon fluconazole administration in a patient with acute myeloblastic leukemia. Am J Hematol 2006; 81:366-369.
4. Pham CP, de Feiter PW, van der Kuy PHM, van Mook WN. Long QTc interval and torsade de pointes caused by fluconazole. Ann Pharmacother 2006; 40:1456-1461. (Pubitemid 44204980)
5. Hohnloser SH, Klingenheben T, Singh BN. Amiodarone-associated proarrhythmic effects. A review with special reference to torsade de pointes tachycardia. Ann Intern Med 1994; 121:529-535.
6. Terrell CL. Antifungal agents. Part II. The azoles. Mayo Clin Proc 1999; 74:78-100.
7. Yap YG, Camm AJ. Drug induced QT prolongation and torsades de pointes. Heart 2003; 89:1363-1372. (Pubitemid 37311108)
8. Makkar RR, Fromm BS, Steinman RT, Meissner MD, Lehmann MH. Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. JAMA 1993; 270:2590-2597. (Pubitemid 23346699)
9. Anaissie EJ, Kontoyiannis DP, Huls C, Vartivarian SE, Karl C, Prince RA et al. Safety, plasma concentrations, and efficacy of high-dose fluconazole in invasive mold infections. J Infect Dis 1995; 172:599-602.
10. Khazan M, Mathis AS. Probable case of torsades de pointes induced by fluconazole. Pharmacotherapy 2002; 22:1632-1637. (Pubitemid 35429958)
11. Eiden C, Peyriere H, Tichit R, Cociglio M, Amedro P, Blayac J-P et al. Inherited long QT syndrome revealed by antifungals drug-drug interaction. J Clin Pharm Ther 2007; 32:321-324. (Pubitemid 46699512)