Mechanism and processing parameters affecting the formation of methyl methanesulfonate from methanol and methanesulfonic acid: an illustrative example for sulfonate ester impurity formation

Organic Process Research and Development

Volumn 13, Issue 3, 2009, Pages 429-433

  Teasdale, Andrew ^a   Eyley, Stephen C ^a   Delaney, Ed ^b   Jacq, Karine ^c   Taylor Worth, Karen ^d   Lipczynski, Andrew ^d   Van, Reif ^e   Elder, David P ^f   Facchine, Kevin L ^g   Golec, Simon ^h   Oestrich, Rolf Schulte ⁱ   Sandra, Pat ^c   David, Frank ^c  

^a ASTRAZENECA   (United Kingdom)

^b Reaction Science Consulting   (United States)

^c Research Institute for Chromatography   (Belgium)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^e MERCK RESEARCH LABORATORIES   (United States)

^f GLAXOSMITHKLINE   (United Kingdom)

^g GLAXOSMITHKLINE   (United States)

^h PFIZER INC   (United States)

ⁱ F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 66249096670     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op800192a     Document Type: Article

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