Flow-induced shear stresses increase the number of cell-cell contacts within extracellular matrix

Journal of Biomedical Materials Research - Part A

Volumn 89, Issue 4, 2009, Pages 968-979

  Kong, Qingjun ^a   Vazquez, Maribel ^a  

^a City College of New York   (United States)

Author keywords

Cell cell contacts; Connexin 43; Extracellular matrix; Pre stressed gel; Shear flow

Indexed keywords

CELL RESPONSE; CELL-CELL CONTACT; CELL-CELL CONTACTS; CONNEXIN 43; CONSTANT FLOW; CYTOPLASMIC PROCESS; ECM FORMATION; EXTERNAL STIMULUS; EXTRACELLULAR MATRICES; EXTRACELLULAR MATRIX; GAP JUNCTIONS; INTERCELLULAR COMMUNICATIONS; MATRIX; MECHANOTRANSDUCTION; PRE-STRESSED; PRE-STRESSED GEL; SEM; SHEAR EFFECT; TIME PERIODS; TISSUE HOMEOSTASIS;

COLLAGEN; CYTOLOGY; ELECTRIC DISCHARGE MACHINING; ENZYME ACTIVITY; GELATION; GELS; INFORMATION DISSEMINATION; MATRIX ALGEBRA; PHYSIOLOGY; SCANNING ELECTRON MICROSCOPY; SHEAR FLOW; SHEAR STRESS; STRENGTH OF MATERIALS; THREE DIMENSIONAL;

CELLS;

COLLAGEN; CONNEXIN 43;

ARTICLE; CELL COMMUNICATION; CELL CONTACT; CELL STRUCTURE; CYTOPLASM; EXTRACELLULAR MATRIX; GAP JUNCTION; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; SHEAR STRESS;

ANIMALS; CATTLE; CELL COMMUNICATION; CELL SURFACE EXTENSIONS; COLLAGEN; ELASTICITY; EXTRACELLULAR MATRIX; FIBROBLASTS; RHEOLOGY; SOLUTIONS; STRESS, MECHANICAL; TIME FACTORS; VISCOSITY;

EID: 66249091964     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31964     Document Type: Article

References (35)

1. Gumbiner BM, Yamada KM. Cell-to-cell contact and extracellular matrix. Curr Opin Cell Biol 1995;7:615-618.
2. Chen CST, Tien J. Mechanotransduction at cell-matrix and cell-cell contacts. Annu Rev Biomed Eng 2004;6:275-302.
3. Woo SL, Jia F, Zou L, Gabriel MT. Functional tissue engineering for ligament healing: Potential of antisense gene therapy. Ann Biomed Eng 2004;32:342-351.
4. Cukierman E., Pankov R, Yamada KM. Cell interactions with three-dimensional matrices. Current Opin Cell Biol 2002; 14: 633-639.
5. DeMali KA, Wennerberg K, Burridge K. Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol 2003;15:572-582.
6. Hynes RO. Cell adhesion: Old and new questions. Trends Cell Biol 1999;9:M33-M77.
7. DeMaliKAWennerberg K, Burridge K. Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol 2003;15:572-582.
8. Jiang H, Grinnell, F. Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices. Mol Biol Cell 2005;16:5070-5076.
9. Robert L. Matrix biology: Past, present and future. Pathol Biol (Paris) 2001;49:279-283.
10. Zavan B, Brun P, Vindigni V, Amadori A, Habeler W, Pon- tisso P, Montemurro D, Abatangelo G, Cortivo R. Extracellular matrix-enriched polymeric scaffolds as a substrate for he- patocyte cultures; In vitro and in vivo studies. Biomaterials 2005;26:7038-7045.
11. Garvin J, Qi J, Maloney M, Banes AJ. Novel system for engineering bioartificial tendons and application of mechanical load. Tissue Eng 2003;9:967-979.
12. O'Brien FJ, Harley BA, Waller MA, Yannas IV, Gibson LJ, Prendergast PJ. The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering. Technol Health Care 2007;15:3-17.
13. Ng CP, Swartz, MA. Mechanisms of interstitial flow-induced remodeling of fibroblast-collagen cultures. Ann Biomed Eng 2006;34:446-454.
14. Thi M, Kojima T, Cowin SC, Weinbaum S, Spray DC. Fluid shear stress remodels expression and function of junctional proteins in cultured bone cells. Am J Physiol Cell Physiol 2002;284:389-403.
15. Cheng B, Zhao S, Luo J, Sprague E, Bonewald LF, Jiang JX. Expression of functional gap junctions and regulation by fluid flow in osteocyte-like MLO-Y4 cells. J Bone Miner Res 2001;16:249-259.
16. DePaola N, Davies PF, Pritchard WF Jr, Florez L, Harbeck N, Polacek DC. Spatial and temporal regulation of gap junction connexin 43 in vascular endothelial cells exposed to controlled disturbed flows in vitro. Proc Natl Acad Sci USA 1999;96:3154-3159.
17. Forgacs G, Newman SA, Hinner B, Maier CW, Sackmann E. Assembly of collagen matrices as a phase transition revealed by structural and rheologic studies. Biophys J 2003;84 (2 Pt 1):1272-1280.
18. Newman S, Cloitre M, Allain C, Forgacs G, Beysens D. Viscosity and elasticity during collagen assembly in vitro: Rele-vance to matrix-driven translocation. Biopolymers 1997;41: 337-347.
19. Ehrlich HP, Diez T. Role for gap junctional intercellular communications in wound repair. Wound Repair Regen 2003; 11:481-489.
20. Callaway GH, Field LD, Deng XH, Torzilli PA, O'Brien SJ, Altchek DW, Warren RF. Biomechanical evaluation of the medial collateral ligament of the elbow. J Bone Joint Surg Am 1997;79:1223-1231.
21. Hung CT, Allen FD, Pollack SR, Attia ET, Hannafin JA, Torzilli PA. Intracellular calcium response of ACL and MCL ligament fibroblasts to fluid-induced shear stress. Cell Signal 1997;9:587-594.
22. Saltzman WM, Parkhurst MR, Parsons-Wingerter P, Zhu WH. Three-dimensional cell cultures mimic tissues. Ann N Y Acad Sci 1992;665:259-273.
23. Wright RW, Allen T, El-Zawawy HB, Brodt MD, Silva MJ, Gill CS, Sandell LJ. Medial collateral ligament healing in macrophage metalloelastase (MMP-12)-deficient mice. J Orthop Res 2006;24:2106-2113.
24. Byron Bird R, Curtiss FC, Armstrong RC, Hassager O. Dynamics of Polymeric Liquids, Vol II., 2nd ed., New York, NY: Wiley Brothers; 1989.
25. Wu CC, Ding S-J, Wang YH, Tang MJ, Chang HC. Mechanical properties of collagen gels derived from rats of different ages. J Biomater Sci Polym Ed 2005;16:1261-1275.
26. Lazouskaya V, Jin Y, Or D. Interfacial interactions and colloid retention under steady flows in a capillary channel. J Colloid Interface Sci 2006;303:171-184.
27. Kong Q, Vazquez M. Internal fluid flow increases cellular interconnects between medial collateral ligament fibroblasts and cellular extensions within three-dimensional collagen matrixes. Cell Commun Adhes 2006;13:139-149.
28. Vazquez M, Schmalzing D, Matsudaira P, Ehrlich D, McKinley G. Shear-induced degradation of linear polyacryl- amide solutions during pre-electrophoretic loading. Anal Chem 2001;73:3035-3044.
29. Lo IK, Ou Y, Rattner JP, Hart DA, Marchuk LL, Frank CB, Rattner JB. The cellular networks of normal ovine medial collateral and anterior cruciate ligaments are not accurately recapitulated in scar tissue. J Anat 2002;200 (Pt 3): 283-296.
30. Pizzo AM, Kokini K, Vaughn LC, Waisner BZ, Voytik-Harbin SL. Extracellular matrix (ECM) microstructural composition regulates local cell-ECM biomechanics and fundamental fibroblast behavior: A multidimensional perspective. J Appl Physiol 2005;98:1909-1921.
31. Tamariz E, Grinnell F. Modulation of fibroblast morphology and adhesion during collagen matrix remodeling. Mol Biol Cell 2002;13:3915-3929.
32. : localized assembly of extracellular matrix integrin ligands requires cell-cell contact. J Cell Sci 2000;113 (Pt 21):3715-3723.
33. Mogilner A. On the edge: Modeling protrusion. Curr Opin Cell Biol 2006;18:32-39.
34. Kang K, Lee LJ, Koelling K. High shear microfluidics and its application in rheological measurement. Exp Fluids 2005;38: 222-232.
35. Saintillan DS, Shaqfeh ES, Darve E. Effect of flexibility on the shear-induced migration of short-chain polymers in parabolic channel flow. J Fluid Mech 2006;557:297-306.