In vivo evaluation of 11-hydroxysteroid dehydrogenase activity in the rabbit eye

Journal of Ocular Pharmacology and Therapeutics

Volumn 25, Issue 3, 2009, Pages 215-221

  Anderson, Scott ^a   Carreiro, Samantha ^a   Quenzer, Terri ^a   Gale, David ^a   Xiang, Cathie ^a   Gukasyan, Hovhannes ^a   Lafontaine, Jennifer ^a   Cheng, Hengmiao ^a   Krauss, Achim ^a   Prasanna, Ganesh ^a,b  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b Pfi Zer Global Research and Development La Jolla   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; ANTIGLAUCOMA AGENT; CORTISONE; HYDROCORTISONE; OXIDOREDUCTASE INHIBITOR; PF 3319913; PF 3859622; PF 904955; UNCLASSIFIED DRUG; GLUCOCORTICOID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG POTENCY; DRUG TISSUE LEVEL; ENZYME INHIBITION; EXPERIMENTAL RABBIT; HORMONE METABOLISM; HUMAN; HUMAN CELL; NONHUMAN; ANIMAL; AQUEOUS HUMOR; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EYE; INTRAOCULAR PRESSURE; LIQUID CHROMATOGRAPHY; METABOLISM; RABBIT; TANDEM MASS SPECTROMETRY; TOPICAL DRUG ADMINISTRATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADMINISTRATION, TOPICAL; ANIMALS; AQUEOUS HUMOR; CHROMATOGRAPHY, LIQUID; CORTISONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EYE; GLUCOCORTICOIDS; HYDROCORTISONE; INTRAOCULAR PRESSURE; RABBITS; TANDEM MASS SPECTROMETRY;

EID: 66249089010     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2008.0120     Document Type: Article

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