Optically sectioned fluorescence endomicroscopy with hybrid-illumination imaging through a flexible fiber bundle

Journal of Biomedical Optics

Volumn 14, Issue 3, 2009, Pages

  Santos, Silvia ^a   Chu, Kengyeh K ^a   Lim, Daryl ^a   Bozinovic, Nenad ^a   Ford, Tim N ^a   Hourtoule, Claire ^a   Bartoo, Aaron C ^b   Singh, Satish K ^b   Mertz, Jerome ^a  

^a Boston University   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endomicroscopy; Fiber bundle imaging; Fluorescence; Microendoscopy; Optical sectioning

Indexed keywords

BACKGROUND REJECTION; COLONIC MUCOSA; ENDOMICROSCOPY; FLEXIBLE FIBERS; HIGH RESOLUTION; IMAGE CONTRASTS; IMAGING FIBER BUNDLE; LOW RESOLUTION; MICROENDOSCOPY; OPTICAL SECTIONING; OUT-OF-FOCUS; PATTERN ILLUMINATION; RESOLUTION IMAGES; UNIFORM ILLUMINATION; WIDE-FIELD;

FLUORESCENCE; INERTIAL CONFINEMENT FUSION;

FIBERS;

RATTUS;

ACRIDINE ORANGE; DIAGNOSTIC AGENT;

ANIMAL; COLON; ENDOSCOPY; FIBER OPTICS; FLUORESCENCE MICROSCOPY; HISTOLOGY; IMAGE ENHANCEMENT; INSTRUMENTATION; INTESTINE MUCOSA; LETTER; METHODOLOGY; RAT;

ACRIDINE ORANGE; ANIMALS; COLON; ENDOSCOPY; FIBER OPTIC TECHNOLOGY; IMAGE ENHANCEMENT; INTESTINAL MUCOSA; MICROSCOPY, FLUORESCENCE; RATS;

EID: 66149173184     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3130266     Document Type: Article

References (11)

1. A. Hoffman, M. Goetz, M. Vieth, P. R. Galle, M. F. Neurath, and R. Kiesslich, "Confocal laser endomicroscopy: technical status and current indications," Endoscopy 38, 1275-1283 (2006).
2. A. R. Rouse and A. F. Gmitro, "Multispectral imaging with a confocal microendoscope," Opt. Let. 25, 1708-1710 (2000).
3. L. D. Swindle, S. G. Thomas, M. Freeman, and P. M. Delaney, "View of normal human skin in vivo as observed using fluorescent fiber-optics confocal microscopic imaging," J. Invest. Dermatol. 121. 706-712 (2003). (Pubitemid 37239111)
4. F. Jean, G. Bourg-Heckly, and B. Viellerobe, "Fibered confocal spectroscopy and multicolor imaging system for in vivo fluorescence analysis," Opt. Express 15, 4008-4017 (2007).
5. H.-J. Shin, M. C. Pierce, D. Lee, H. Ra, O. Solgaard, and R. Richards-Kortum, "Fiber-optic confocal microscope using MEMS scanner and miniature objective lens," Opt. Express 15, 9113-9122 (2007).
6. J. T. C. Liu, M. J. Mandella, H. Ra, L. K. Wong, O. Solgaard, G. S. Kino, W. Piyawattanametha, C. H. Contag, and T. D. Wang, "Miniature near-infrared dual-axes confocal microscope utilizing two-dimensional microelectromechanical systems scanner," Opt. Ltt. 32, 256-258 (2007). (Pubitemid 46339962)
7. B. Flusberg, E. Cocker, W. Piyawattanametha, J. Jung, E. Cheung, and M. Schnitzer, "Fiber-optic fluorescence imaging," Nat. Methods 2, 941-950 (2005). (Pubitemid 43108730)
8. P. Kim, M. Puoris'haag, D. Cote, C. P. Lin, and S. H. Yun, "In vivo confocal and multiphoton microendoscopy," J. Biomed. Opt. 13, 010501 (2008).
9. D. Karadaglic, R. Juškaitis, and T. Wilson, "Confocal endoscopy via Structured Illumination," Scanning 24, 301-304 (2002). (Pubitemid 36008564)
10. N. Bozinovic, C. Ventalon, T. Ford, and J. Mertz, "Fluorescence endomicroscopy with structured illumination," Opt. Express 16, 8016-8025 (2008).
11. D. Lim, K. K. Chu, and J. Mertz, "Wide-field fluorescence sectioning with hybrid speckle and uniform-illumination microscopy," Opt. Lett. 33, 1819-1821 (2008).