-
1
-
-
0036882390
-
Structure and mechanism of the pepsin-like family of aspartic peptidases
-
Dunn BM. Structure and mechanism of the pepsin-like family of aspartic peptidases. Chem Rev 2002;102:4431-4458.
-
(2002)
Chem Rev
, vol.102
, pp. 4431-4458
-
-
Dunn, B.M.1
-
2
-
-
0032989422
-
Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2-epimerase
-
Takahashi S, Takahashi K, Kaneko T, Ogasawara H, Shindo S, Kobayashi M. Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2-epimerase. J Biochem (Tokyo) 1999;125:348-353. (Pubitemid 29112301)
-
(1999)
Journal of Biochemistry
, vol.125
, Issue.2
, pp. 348-353
-
-
Takahashi, S.1
Takahashi, K.2
Kaneko, T.3
Ogasawara, H.4
Shindo, S.5
Kobayashi, M.6
-
3
-
-
0032079894
-
Molecular cloning, expression and characterization of an Ascaris inhibitor for pepsin and cathepsin e
-
Kageyama T. Molecular cloning, expression and characterisation of an Ascaris inhibitor for pepsin and cathepsin E. Eur J Biochem 1998;253:804-809. (Pubitemid 28223551)
-
(1998)
European Journal of Biochemistry
, vol.253
, Issue.3
, pp. 804-809
-
-
Kageyama, T.1
-
4
-
-
0036538790
-
Aspartic proteinase inhibitors from tomato and potato are more potent against yeast proteinase a than cathepsin D
-
DOI 10.1016/S0167-4838(02)00206-6, PII S0167483802002066
-
Cater SA, Lees WE, Hill J, Brzin J, Kay J, Phylip LH. Aspartic proteinase inhibitors from tomato and potato are more potent against yeast proteinase A than cathepsin D. Biochim Biophys Acta 2002;1596:76-82. (Pubitemid 34450842)
-
(2002)
Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology
, vol.1596
, Issue.1
, pp. 76-82
-
-
Cater, S.A.1
Lees, W.E.2
Hill, J.3
Brzin, J.4
Kay, J.5
Phylip, L.H.6
-
5
-
-
0032523769
-
Purification, characterization and cloning of an aspartic proteinase inhibitor from squash phloem exudate
-
Christeller JT, Farley PC, Ramsay RJ, Sullivan PA, Laing WA. Purification, characterization and cloning of an aspartic proteinase inhibitor from squash phloem exudate. Eur J Biochem 1998;254:160-167. (Pubitemid 28255083)
-
(1998)
European Journal of Biochemistry
, vol.254
, Issue.1
, pp. 160-167
-
-
Christeller, J.T.1
Farley, P.C.2
Ramsay, R.J.3
Sullivan, P.A.4
Laing, W.A.5
-
6
-
-
0016136860
-
Urification and characterization of macromolecular inhibitors of proteinase A from yeast
-
Saheki T, Matsuda Y, Holzer H. Urification and characterization of macromolecular inhibitors of proteinase A from yeast. Eur J Biochem 1974;47:325-332.
-
(1974)
Eur J Biochem
, vol.47
, pp. 325-332
-
-
Saheki, T.1
Matsuda, Y.2
Holzer, H.3
-
7
-
-
84944045394
-
-
Barrett AJ, Rawlings ND, Woessner JF, editors. London: Elsevier Academic Press
-
Winther JR, Phylip LH, Kay J. Handbook of proteolytic enzymes. In: Barrett AJ, Rawlings ND, Woessner JF, editors. London: Elsevier Academic Press; 2004. pp 87-91.
-
(2004)
Handbook of Proteolytic Enzymes
, pp. 87-91
-
-
Winther, J.R.1
Phylip, L.H.2
Kay, J.3
-
8
-
-
1842531458
-
3, An Aspartic Proteinase Inhibitor from Saccharomyces cerevisiae, Is Intrinsically Unstructured in Solution
-
DOI 10.1021/bi034823n
-
Green TB, Ganesh O, Perry K, Smith L, Phylip LH, Logan TM, Hagen SJ, Dunn BM, Edison AS. IA3, an aspartic proteinase inhibitor from Saccharomyces cerevisiae, is intrinsically unstructured in solution. Biochemistry 2004;43:4071-4081. (Pubitemid 38445626)
-
(2004)
Biochemistry
, vol.43
, Issue.14
, pp. 4071-4081
-
-
Green, T.B.1
Ganesh, O.2
Perry, K.3
Smith, L.4
Phylip, L.H.5
Logan, T.M.6
Hagen, S.J.7
Dunn, B.M.8
Edison, A.S.9
-
9
-
-
0033950453
-
The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix
-
DOI 10.1038/72378
-
Li M, Phylip LH, Lees WE, Winther JR, Dunn BM, Wlodawer A, Kay J, Gustchina A. The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat Struct Biol 2000;7:113-117. (Pubitemid 30082507)
-
(2000)
Nature Structural Biology
, vol.7
, Issue.2
, pp. 113-117
-
-
Li, M.1
Phylip, L.H.2
Lees, W.E.3
Winther, J.R.4
Dunn, B.M.5
Wlodawer, A.6
Kay, J.7
Gustchina, A.8
-
10
-
-
0035910410
-
3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae
-
DOI 10.1074/jbc.M008520200
-
Phylip LH, Lees WE, Brownsey BG, Bur D, Dunn BM, Winther JR, Gustchina A, Li M, Copeland T, Wlodawer A, Kay J. The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae.. J Biol Chem 2001;276:2023-2030. (Pubitemid 32109682)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.3
, pp. 2023-2030
-
-
Phylip, L.H.1
Leesa, W.E.2
Brownsey, B.G.3
Bur, D.4
Dunn, B.M.5
Winther, J.R.6
Gustchina, A.7
Li, M.8
Copeland, T.9
Wlodawer, A.10
Kay, J.11
-
11
-
-
33746907152
-
Adaptation of the behaviour of an aspartic proteinase inhibitor by relocation of a lysine residue by one helical turn
-
DOI 10.1515/BC.2006.140, PII BCHM38781139
-
Winterburn TJ, Wyatt DM, Phylip LH, Berry C, Bur D, Kay J. Adaptation of the behaviour of an aspartic proteinase inhibitor by re-location of a lysine residue by one helical turn. Biol Chem 2006;387:1139-1142. (Pubitemid 44200509)
-
(2006)
Biological Chemistry
, vol.387
, Issue.8
, pp. 1139-1142
-
-
Winterburn, T.J.1
Wyatt, D.M.2
Phylip, L.H.3
Berry, C.4
Bur, D.5
Kay, J.6
-
12
-
-
34250346537
-
3 polypeptide
-
DOI 10.1074/jbc.M610503200
-
Winterburn TJ, Wyatt DM, Phylip LH, Bur D, Harrison RJ, Berry C, Kay J. Key features determining the specificity of aspartic proteinase inhibition by the helix-forming IA3 polypeptide. J Biol Chem 2007;282:6508-6516. (Pubitemid 47100851)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.9
, pp. 6508-6516
-
-
Winterburn, T.J.1
Wyatt, D.M.2
Phylip, L.H.3
Bur, D.4
Harrison, R.J.5
Berry, C.6
Kay, J.7
-
13
-
-
34447330438
-
3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity
-
DOI 10.1111/j.1742-4658.2007.05901.x
-
Winterburn TJ, Phylip LH, Bur D, Wyatt DM, Berry C, Kay J. N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity. Febs J 2007;274:3685-3694. (Pubitemid 47052406)
-
(2007)
FEBS Journal
, vol.274
, Issue.14
, pp. 3685-3694
-
-
Winterburn, T.J.1
Phylip, L.H.2
Bur, D.3
Wyatt, D.M.4
Berry, C.5
Kay, J.6
-
14
-
-
0030771347
-
QSAR and 3D QSAR in drug design. I. Methodology
-
Kubinyi H. QSAR and 3D QSAR in drug design. I. Methodology. Drug Discov Today 1997;2:457-467.
-
(1997)
Drug Discov Today
, vol.2
, pp. 457-467
-
-
Kubinyi, H.1
-
15
-
-
0033959235
-
Quantitative structure-property relationships in pharmaceutical research - Part 1
-
DOI 10.1016/S1461-5347(99)00214-X, PII S146153479900214X
-
Grover II, Singh II, Bakshi II. Quantitative structure-property relationships in pharmaceutical research - part 1. Pharm Sci Technol Today 2000;3:28-35. (Pubitemid 30066492)
-
(2000)
Pharmaceutical Science and Technology Today
, vol.3
, Issue.1
, pp. 28-35
-
-
Grover, M.1
Singh, B.2
Bakshi, M.3
Singh, S.4
-
16
-
-
34250665836
-
Encoding type and position in peptide QSAR: Application to peptides binding to class I MHC molecule HLA-A*0201
-
DOI 10.1002/qsar.200530184
-
Pissurlenkar RRS, Malde AK, Khedkar SA, Continho EC. Encoding type and position in peptide QSAR: application to peptide binding to class I MHC molecule HLA-A•0201. QSAR Comb Sci 2007;26:189-203. (Pubitemid 46931730)
-
(2007)
QSAR and Combinatorial Science
, vol.26
, Issue.2
, pp. 189-203
-
-
Pissurlenkar, R.R.S.1
Malde, A.K.2
Khedkar, S.A.3
Coutinho, E.C.4
-
17
-
-
0025811052
-
Minimum analogue peptide sets (MAPS) for quantitative structure-activity relationships
-
Hellberg S, Eriksson L, Jonsson J, Lindgren F, Sjostrom M, Skagerberg B, Wold S, Andrews P. Minimum analogue peptide sets (MAPS) for quantitative structure-activity relationships. Int J Pept Protein Res 1991;37:414-424.
-
(1991)
Int J Pept Protein Res
, vol.37
, pp. 414-424
-
-
Hellberg, S.1
Eriksson, L.2
Jonsson, J.3
Lindgren, F.4
Sjostrom, M.5
Skagerberg, B.6
Wold, S.7
Andrews, P.8
-
18
-
-
0030914453
-
A quantitative structure-activity relationship study of some substance P-related peptides. a multivariate approach using PLS and variable selection
-
Norinder U, Rivera C, Unden A. A quantitative structure-activity relationship study of some substance P-related peptides. A multivariate approach using PLS and variable selection. J Pept Res 1997;49:155-162. (Pubitemid 27280092)
-
(1997)
Journal of Peptide Research
, vol.49
, Issue.2
, pp. 155-162
-
-
Norinder, U.1
Rivera, C.2
Unden, A.3
-
19
-
-
33747674319
-
Design of novispirin antimicrobial peptides by quantitative structure-activity relationship
-
DOI 10.1111/j.1747-0285.2006.00405.x
-
Taboureau O, Olsen OH, Nielsen JD, Raventos D, Mygind PH, Kristensen HH. Design of novispirin antimicrobial peptides by quantitative structure-activity relationship. Chem Biol Drug Des 2006;68:48-57. (Pubitemid 44272819)
-
(2006)
Chemical Biology and Drug Design
, vol.68
, Issue.1
, pp. 48-57
-
-
Taboureau, O.1
Olsen, O.H.2
Nielsen, J.D.3
Raventos, D.4
Mygind, P.H.5
Kristensen, H.-H.6
-
20
-
-
33846535504
-
Quantitative structure-activity relationship study of bitter peptides
-
DOI 10.1021/jf062422j
-
Kim HO, Li-Chan EC. Quantitative structure-activity relationship study of bitter peptides. J Agric Food Chem 2006;54:10102-10111. (Pubitemid 46159016)
-
(2006)
Journal of Agricultural and Food Chemistry
, vol.54
, Issue.26
, pp. 10102-10111
-
-
Kim, H.-O.1
Li-Chan, E.C.Y.2
-
21
-
-
0036276410
-
QSAR studies applied to the prediction of antigen-antibody interaction kinetics as measured by BIACORE
-
Choulier L, Andersson K, Hamalainen MD, van Regenmortel MH, Malmqvist M, Altschuh D. QSAR studies applied to the prediction of antigen-antibody interaction kinetics as measured by BIACORE. Protein Eng 2002;15:373-382. (Pubitemid 34601729)
-
(2002)
Protein Engineering
, vol.15
, Issue.5
, pp. 373-382
-
-
Choulier, L.1
Andersson, K.2
Hamalainen, M.D.3
Van Regenmortel, M.H.V.4
Malmqvist, M.5
Altschuh, D.6
-
22
-
-
33846669447
-
Quantitative structure-activity relationship study of bitter di- And tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity
-
DOI 10.1002/psc.800
-
Wu J, Aluko RE. Quantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity. J Pept Sci 2007;13:63-69. (Pubitemid 46190035)
-
(2007)
Journal of Peptide Science
, vol.13
, Issue.1
, pp. 63-69
-
-
Wu, J.1
Aluko, R.E.2
-
23
-
-
33244488716
-
Structural requirements of angiotensin I-converting enzyme inhibitory peptides: Quantitative structure-activity relationship study of Di- And tripeptides
-
DOI 10.1016/j.jmaa.2005.05.084
-
Wu J, Aluko RE, Nakai S. Structural requirements of Angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides. J Agric Food Chem 2006;54:732-738. (Pubitemid 43274109)
-
(2006)
Journal of Agricultural and Food Chemistry
, vol.54
, Issue.3
, pp. 732-738
-
-
Wu, J.1
Aluko, R.E.2
Nakai, S.3
-
24
-
-
0842332242
-
The signature molecular descriptor: 3. Inverse-quantitative structure-activity relationship of ICAM-1 inhibitory peptides
-
DOI 10.1016/j.jmgm.2003.10.002
-
Churchwell CJ, Rintoul MD, Martin S, Visco DP Jr, Kotu A, Larson RS, Sillerud LO, Brown DC, Faulon JL. The signature molecular descriptor. III. Inverse-quantitative structure-activity relationship of ICAM-1 inhibitory peptides. J Mol Graph Model 2004;22:263-273. (Pubitemid 38183096)
-
(2004)
Journal of Molecular Graphics and Modelling
, vol.22
, Issue.4
, pp. 263-273
-
-
Churchwell, C.J.1
Rintoul, M.D.2
Martin, S.3
Visco Jr., D.P.4
Kotu, A.5
Larson, R.S.6
Sillerud, L.O.7
Brown, D.C.8
Faulon, J.-L.9
-
25
-
-
0033812175
-
Mathematical modelling of insect neuropeptide potencies. Are quantitatively predictive models possible?
-
Lee MJ, de Jong S, Gade G, Poulos C, Goldsworthy GJ. Mathematical modelling of insect neuropeptide potencies. Are quantitatively predictive models possible? Insect Biochem Mol Biol 2000;30:899-907.
-
(2000)
Insect Biochem Mol Biol
, vol.30
, pp. 899-907
-
-
Lee, M.J.1
De Jong, S.2
Gade, G.3
Poulos, C.4
Goldsworthy, G.J.5
-
27
-
-
0042355453
-
Rational selection of training and test sets for the development of validated QSAR models
-
DOI 10.1023/A:1025386326946
-
Golbraikh A, Shen M, Xiao Z, Xiao YD, Lee KH, Tropsha A. Rational selection of training and test sets for the development of validated QSAR models. J Comput Aided Mol Des 2003;17:241-253. (Pubitemid 37062785)
-
(2003)
Journal of Computer-Aided Molecular Design
, vol.17
, Issue.2-4
, pp. 241-253
-
-
Golbraikh, A.1
Shen, M.2
Xiao, Z.3
Xiao, Y.-D.4
Lee, K.-H.5
Tropsha, A.6
-
28
-
-
0031473847
-
SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
-
DOI 10.1002/elps.1150181505
-
Guex N, Peitsch MC. SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 1997;18:2714-2723. (Pubitemid 28059943)
-
(1997)
Electrophoresis
, vol.18
, Issue.15
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
29
-
-
0033135638
-
Effective energy function for proteins in solution
-
DOI 10.1002/(SICI)1097-0134(19990501)35:2<133::AID-PROT1>3.0.CO;2-N
-
Lazaridis T, Karplus M. Effective energy function for proteins in solution. Proteins 1999;35:133-152. (Pubitemid 29165128)
-
(1999)
Proteins: Structure, Function and Genetics
, vol.35
, Issue.2
, pp. 133-152
-
-
Lazaridis, T.1
Karplus, M.2
-
30
-
-
14144256681
-
Energy functions for protein design: Adjustment with protein-protein complex affinities, models for the unfolded state, and negative design of solubility and specificity
-
DOI 10.1016/j.jmb.2004.12.019
-
Pokala N, Handel TM. Energy functions for protein design: adjustment with protein-protein complex affinities, models for the unfolded state, and negative design of solubility and specificity. J Mol Biol 2005;347:203-227. (Pubitemid 40283639)
-
(2005)
Journal of Molecular Biology
, vol.347
, Issue.1
, pp. 203-227
-
-
Pokala, N.1
Handel, T.M.2
-
32
-
-
0032474777
-
New chemical descriptors relevant for the design of biologically active peptides. a multivariate characterization of 87 amino acids
-
DOI 10.1021/jm9700575
-
Sandberg M, Eriksson L, Jonsson J, Sjostrom M, Wold S. New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids. J Med Chem 1998;41:2481-2491. (Pubitemid 28321898)
-
(1998)
Journal of Medicinal Chemistry
, vol.41
, Issue.14
, pp. 2481-2491
-
-
Sandberg, M.1
Eriksson, L.2
Jonsson, J.3
Sjostrom, M.4
Wold, S.5
-
33
-
-
0033997037
-
Structure-based thermodynamic analysis of the dissociation of protein phosphatase-1 catalytic subunit and microcystin-LR docked complexes
-
Lavigne P, Bagu JR, Boyko R, Willard L, Holmes CF, Sykes BD. Structure-based thermodynamic analysis of the dissociation of protein phosphatase-1 catalytic subunit and microcystin-LR docked complexes. Protein Sci 2000;9:252-264. (Pubitemid 30126998)
-
(2000)
Protein Science
, vol.9
, Issue.2
, pp. 252-264
-
-
Lavigne, P.1
Bagu, J.R.2
Boyko, R.3
Willard, L.4
Holmes, C.F.B.5
Sykes, B.D.6
-
34
-
-
23144436398
-
The FoldX web server: An online force field
-
DOI 10.1093/nar/gki387
-
Schymkowitz J, Borg J, Stricher F, Nys R, Rousseau F, Serrano L. The FoldX web server: an online force field. Nucleic Acids Res 2005;33:W382-W388. (Pubitemid 44529948)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.WEB. SERV. ISS.
-
-
Schymkowitz, J.1
Borg, J.2
Stricher, F.3
Nys, R.4
Rousseau, F.5
Serrano, L.6
-
35
-
-
2942694535
-
The dependence of all-atom statistical potentials on structural training database
-
DOI 10.1529/biophysj.103.035998
-
Zhang C, Liu S, Zhou H, Zhou Y. The dependence of all-atom statistical potentials on structural training database. Biophys J 2004;86:3349-3358. (Pubitemid 38780222)
-
(2004)
Biophysical Journal
, vol.86
, Issue.6
, pp. 3349-3358
-
-
Zhang, C.1
Liu, S.2
Zhou, H.3
Zhou, Y.4
-
38
-
-
0033923367
-
Rational design of faster associating and tighter binding protein complexes
-
DOI 10.1038/76744
-
Selzer T, Albeck S, Schreiber G. Rational design of faster associating and tighter binding protein complexes. Nat Struct Biol 2000;7:537-541. (Pubitemid 30445907)
-
(2000)
Nature Structural Biology
, vol.7
, Issue.7
, pp. 537-541
-
-
Selzer, T.1
Albeck, S.2
Schreiber, G.3
-
39
-
-
0000026339
-
Orthogonal molecular descriptors
-
Randic M. Orthogonal molecular descriptors. New J Chem 1991;15:517-525.
-
(1991)
New J Chem
, vol.15
, pp. 517-525
-
-
Randic, M.1
-
40
-
-
33745056174
-
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor
-
DOI 10.1073/pnas.0510187103
-
van der Sloot AM, Tur V, Szegezdi E, Mullally MM, Cool RH, Samali A, Serrano L, Quax WJ. Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor. Proc Natl Acad Sci USA 2006;103:8634-8639. (Pubitemid 43878072)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.23
, pp. 8634-8639
-
-
Van Der Sloot, A.M.1
Tur, V.2
Szegezdi, E.3
Mullally, M.M.4
Cool, R.H.5
Samali, A.6
Serrano, L.7
Quax, W.J.8
|