Prevalence of deafness in dogs heterozygous or homozygous for the merle allele

Journal of Veterinary Internal Medicine

Volumn 23, Issue 2, 2009, Pages 282-286

  Strain, G M ^a   Clark, L A ^b   Wahl, J M ^b   Turner, A E ^a   Murphy, K E ^b,c  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c CLEMSON UNIVERSITY   (United States)

Author keywords

Allele; Genotype; Piebald; SILV

Indexed keywords

ANIMALIA; CANIS FAMILIARIS; SIDEROXYLON SALICIFOLIUM;

DNA;

ALLELE; ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMISTRY; DOG; DOG DISEASE; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; GENETICS; GENOTYPE; HEARING IMPAIRMENT; MALE; POLYMERASE CHAIN REACTION; PREVALENCE;

ALLELES; ANIMALS; DEAFNESS; DNA; DOG DISEASES; DOGS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; GENOTYPE; MALE; POLYMERASE CHAIN REACTION; PREVALENCE;

EID: 66149146341     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2008.0257.x     Document Type: Article

References (15)

1. Strain GM. Aetiology, prevalence, and diagnosis of deafness in dogs and cats. Br Vet J 1996;152:17-36.
2. Strain GM. Deafness prevalence and pigmentation and gender associations in dog breeds at risk. Vet J 2004;167:23-32.
3. Cargill EJ, Famula TR, Strain GM, et al. Heritability and segregation analysis of deafness in U.S. Dalmatians. Genetics 2004;166:1385-1393.
4. Famula TR, Cargill EG, Strain GM. Heritability and complex segregation analysis of deafness in Jack Russell Terriers. BMC Vet Res 2007;3:31 (11 pp). Available at: http://www.biomedcentral.com/1746-6148/3/31.
5. Clark LA, Wahl JM, Rees CA, et al. Retrotransposon insertion in SILV is responsible for merle patterning of the domestic dog. Proc Nat Acad Sci 2006;103:1376-1381.
6. Reetz I, Stecker M, Wegner W. Audiometrische Befunde in einer Merlezucht [Audiometric findings in dachshonds (merle gene carriers)]. Dtsch Tierärztliche Wochenschrift 1977;84:273-277.
7. Platt S, Freeman J, di Stefani A, et al. Prevalence of unilateral and bilateral deafness in border collies and association with phenotype. J Vet Intern Med 2006;20:1355-1362.
8. Wilson WJ, Mills PC. Brainstem auditory-evoked responses in dogs. Am J Vet Res 2005;66:2177-2187.
9. Karlsson EK, Baranowska I, Wade CM, et al. Efficient mapping of Mendelian traits in dogs through genome-wide association. Nat Genet 2007;39:1321-1328.
10. Schmutz SM, Berryere TG. Genes affecting coat colour and pattern in domestic dogs. Anim Genet 2007;38:539-549.
11. Igarashi M, Alford BR, Cohn AM, et al. Inner ear abnormalities in dogs. Ann Otol Rhinol Laryngol 1972;81:249-255.
12. Coppens AG, Resibois A, Poncelet L. Bilateral deafness in a Maltese terrier and a Great Pyrenean puppy: Inner ear morphology. J Comp Pathol 2000;122:223-228.
13. Peterson APG. Hearing damage from noise exposure. In: Handbook of Noise Measurement. Chapter 3. Concord, MA: Gen- Rad Inc; 17-24.
14. Du J, Miller AJ, Widlund HR, et al. MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. Am J Pathol 2003;163: 333-343.
15. Stritzel S, Wohlke A, Distl O. Elimination of SILV as a candidate for congenital sensorineural deafness in Dalmatian dogs. Anim Genet 2007;38:662-663.