Influence of rapid malaria diagnostic tests on treatment and health outcome in fever patients, Zanzibar - A crossover validation study

PLoS Medicine

Volumn 6, Issue 4, 2009, Pages

  Msellem, Mwinyi I ^a,b   Mårtensson, Andreas ^b,c   Rotllant, Guida ^d   Bhattarai, Achuyt ^b   Strömberg, Johan ^b   Kahigwa, Elizeus ^e   Garcia, Montse ^d   Petzold, Max ^f   Olumese, Peter ^g   Ali, Abdullah ^a   Björkman, Anders ^b  

^a Ministry of Health Zanzibar   (Tanzania)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d MÉDECINS SANS FRONTIÈRES   (Switzerland)

^e World Health Organisation United Republic of Tanzania   (Tanzania)

^f NORDIC SCHOOL OF PUBLIC HEALTH   (Sweden)

^g WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMODIAQUINE PLUS ARTESUNATE; AMOXICILLIN; AMPICILLIN; ANTIPYRETIC AGENT; COTRIMOXAZOLE; ERYTHROMYCIN; FANSIDAR; PARACETAMOL; QUININE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIAGNOSTIC TEST; FEMALE; FEVER; HEALTH CARE COST; HUMAN; MAJOR CLINICAL STUDY; MALARIA; MALARIA FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; TANZANIA; VALIDATION PROCESS;

ADULT; ANTIMALARIALS; ARTEMISININS; CHILD; CHILD, PRESCHOOL; CROSS-OVER STUDIES; DIAGNOSTIC TESTS, ROUTINE; DRUG THERAPY, COMBINATION; FEVER; HUMANS; MALARIA, FALCIPARUM; ODDS RATIO; PRESCRIPTIONS; TANZANIA; TREATMENT OUTCOME;

EID: 66149141396     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1000070     Document Type: Article

References (28)

1. Bjorkman A, Bhattarai A (2005) Public health impact of drug resistant Plasmodium falciparum malaria. Acta Trop 94: 163-169. (Pubitemid 40720323)
2. Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI (2005) The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434: 214-217. (Pubitemid 40388051)
3. Bojang KA, Obaro S, Morison LA, Greenwood BM (2000) A prospective evaluation of a clinical algorithm for the diagnosis of malaria in Gambian children. Trop Med Int Health 5: 231-236. (Pubitemid 30316796)
4. Chandramohan D, Jaffar S, Greenwood B (2002) Use of clinical algorithms for diagnosing malaria. Trop Med Int Health 7: 45-52. (Pubitemid 34131810)
5. Luxemburger C, Nosten F, Kyle DE, Kiricharoen L, Chongsuphajaisiddhi T, et al. (1998) Clinical features cannot predict a diagnosis of malaria or differentiate the infecting species in children living in an area of low transmission. Trans R Soc Trop Med Hyg 92: 45-49. (Pubitemid 28073728)
6. Redd SC, Kazembe PN, Luby SP, Nwanyanwu O, Hightower AW, et al. (1996) Clinical algorithm for treatment of Plasmodium falciparum malaria in children. Lancet 347: 223-227. (Pubitemid 26035247)
7. Kallander K, Nsungwa-Sabiiti J, Peterson S (2004) Symptom overlap for malaria and pneumonia-policy implications for home management strategies. Acta Trop 90: 211-214. (Pubitemid 38283771)
8. Font F, Alonso Gonzalez M, Nathan R, Nathan R, Kimario J, et al. (2001) Diagnostic accuracy and case management of clinical malaria in the primary health services of a rural area in south-eastern Tanzania. Trop Med Int Health 6: 423-428. (Pubitemid 32525659)
9. Zurovac D, Midia B, Ochola SA, English M, Snow RW (2006) Microscopy and outpatient malaria case management among children and adults in Kenya. Trop Med Int Health 11: 432-440.
10. WHO (2007) Malaria Rapid Diagnosis: Making it work RS/2003/GE/05(PHL). Available: http://www.who.int/malaria/cmc-upload/0/000/016/750/rdt2.pdf. Accessed 9 October 2007.
11. Moody A (2002) Rapid diagnostic tests for malaria parasites. Clin Microbiol Rev 15: 66-78. (Pubitemid 34052582)
12. Murray CK, Bell D, Gasser RA, Wongsrichanalai C (2003) Rapid diagnostic testing for malaria. Trop Med Int Health 8: 876-883. (Pubitemid 37305001)
13. Ochola LB, Vounatsou P, Smith T, Mabaso ML, Newton CR (2006) The reliability of diagnostic techniques in the diagnosis and management of malaria in the absence of a gold standard. Lancet Infect Dis 6: 582-588. (Pubitemid 44246879)
14. Noedl H, Yingyuen K, Laoboonchai A, Fukuda M, Sirichaisinthop J, et al. (2006) Sensitivity and specificity of an antigen detection ELISA for malaria diagnosis. Am J Trop Hyg 75: 1205-1208.
15. Reyburn H, Mbakilwa H, Mwangi R, Mwerinde O, Olomi R, et al. (2007) Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial. BMJ 334: 403. (Pubitemid 46374647)
16. Mason DP, Kawamoto F, Lin K, Laoboonchai A, Wongsrichanalai CA (2002) A comparison of two rapid field immunochromatographic tests to expert microscopy in the diagnosis of malaria. Acta Trop 82: 51-59. (Pubitemid 34246259)
17. Olaleye BO, Williams LA, D'Alessandro U, Weber MM, Mulholland K, et al. (1998) Clinical predictors of malaria in Gambian children with fever or a history of fever. Trans R Soc Trop Med Hyg 92: 300-304. (Pubitemid 28286930)
18. WHO (2007) WHO Guidelines for the treatment of malaria. WHO/HTM/MAL/2006.1108. Available: http://www.who.int/malaria/docs/ TreatmentGuidelines2006.pdf. Accessed 20 March 2009.
19. Guthmann JP, Ruiz A, Priotto G, Kiguli J, Bonte L, et al. (2002) Validity, reliability and ease of use in the field of five rapid tests for the diagnosis of Plasmodium falciparum malaria in Uganda. Trans R Soc Trop Med Hyg 96: 254-257.
20. Hamer DH, Ndhlovu M, Zurovac D, Fox M, Yeboah-Antwi K, et al. (2007) Improved diagnostic testing and malaria treatment practices in Zambia. JAMA 297: 2227-2231. (Pubitemid 47010880)
21. D'Acremont V, Lengeler C, Genton B (2007) Stop ambiguous messages on malaria diagnosis. BMJ 334: 489. (Pubitemid 46588132)
22. Lubell Y, Reyburn H, Mbakilwa H, Mwangi R, Chonya S, et al. (2008) The impact of response to the results of diagnostic tests for malaria: cost-benefit analysis. BMJ 336: 202-205.
23. Bhattarai A, Ali AS, Kachur P, Mårtensson A, Abbas AK, et al. (2007) Impact of artemisinin-based combination therapy and insecticide treated nets on malaria burden in Zanzibar. PLoS Med 4(11): e309. doi:10.1371/journal. pmed.0040309. (Pubitemid 350220531)
24. Mårtensson A, Strömberg J, Sisowath C, Msellem MI, Gil JP, et al. (2005) Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania. Clin Infect Dis 41: 1079-1086. (Pubitemid 41429468)
25. International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (1996) Guideline for Good Clinical Practice. Available: http://www.ich.org/LOB/media/MEDIA482.pdf. Accessed: 30 March 2009.
26. WHO (1991) Basic Malaria Microscopy. Geneva: WHO.
27. Rooth I, Bjorkman A (1992) Fever episodes in a holoendemic malaria area of Tanzania: parasitological and clinical findings and diagnostic aspects related to malaria. Trans R Soc Trop Med Hyg 86: 479-482.
28. McMorrow ML, Masanja MI, Abdulla SMK, Kahigwa E, Kachur SP (2008) Challenges in Routine Implementation and Quality Control of Rapid Diagnostic Tests for Malaria-Rufiji District, Tanzania. Am J Trop Med Hyg 79: 385-390.