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Volumn 28, Issue 3, 2009, Pages 325-337

Fragment-based QSAR and molecular modeling studies on a series of discodermolide analogs as microtubule-stabilizing anticancer agents

(3) Salum, Lívia B a Dias, Luiz C b Andricopulo, Adriano D a

a UNIVERSITY OF SÃO PAULO (Brazil)

b UNIVERSITY OF CAMPINAS (Brazil)

Author keywords

Cancer; Drug design; Microtubule; QSAR; Tubulin

Indexed keywords

MOLECULAR GRAPHICS; MOLECULAR MODELING; PATTERN RECOGNITION; RATIONAL FUNCTIONS; STRUCTURAL DESIGN; TOXICITY;

ANTI-CANCER AGENTS; ANTI-CANCER THERAPIES; CANCER; DISCODERMOLIDE; DRUG DESIGN; MECHANISM OF ACTION; MICROTUBULES; MOLECULAR MODELING STUDIES; QSAR; Β-TUBULIN;

COMPUTATIONAL CHEMISTRY;

ANTINEOPLASTIC AGENT; DICTYOSTATIN; DISCODERMOLIDE; DISCODERMOLIDE DERIVATIVE; EPOTHILONE A; PACLITAXEL; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; DRUG RECEPTOR BINDING; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE; MOLECULAR MODEL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 66149141031 PISSN: 1611020X EISSN: 16110218 Source Type: Journal
DOI: 10.1002/qsar.200860109 Document Type: Article

Times cited : (19)

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