Insight into inhibitory activity of mycobacterial dihydrofolate reductase inhibitors by in-silico molecular modeling approaches

QSAR and Combinatorial Science

Volumn 28, Issue 3, 2009, Pages 296-311

  Bag, Seema ^a   Tawari, Nilesh R ^a   Degani, Mariam S ^a  

^a UNIVERSITY OF MUMBAI   (India)

Author keywords

CoMFA; CoMSIA; DHFR; Homology modeling; Pharmacophore mapping

Indexed keywords

COMPUTATIONAL CHEMISTRY; ENZYME INHIBITION; MAPPING; PHARMACODYNAMICS;

3D-QSAR; COMFA; COMSIA; DHFR; DIHYDROFOLATE REDUCTASE; HOMOLOGY MODELING; INHIBITORY ACTIVITY; PHARMACOPHORE MAPPING; QSAR STUDIES; REDUCTASE INHIBITORS;

MOLECULAR MODELING;

DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR;

ARTICLE; COMPUTER MODEL; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR MODEL; MYCOBACTERIUM INTRACELLULARE AVIUM; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SEQUENCE HOMOLOGY;

MYCOBACTERIUM AVIUM COMPLEX;

EID: 66149138845     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200860067     Document Type: Article

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