Exposure to a mri-type high-strength static magnetic field stimulates megakaryocytic/erythroid hematopoiesis in cd34+ cells from human placental and umbilical cord blood

Bioelectromagnetics

Volumn 30, Issue 4, 2009, Pages 280-285

  Monzen, Satoru ^a   Takahashi, Kenji ^a   Tok, Tsutomu ^b   Ito, Etsuro ^b   Sakurai, Tomonori ^a   Miyakoshi, Junji ^a   Kashiwakura, Ikuo ^a  

^a Division of Medical Life Sciences   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

CD34 cells; Hematopoietic progenitor cells; Megakaryocytic erythroid hematopoiesis; Mri; Static magnetic fields

Indexed keywords

BLOOD; CYTOLOGY; GENE EXPRESSION; MAGNETIC FIELD EFFECTS; STEM CELLS;

CD34+ CELLS; FIELD EXPOSURE; HAEMATOPOIESIS; HEMATOPOIETIC PROGENITOR CELLS; HIGH-STRENGTH; MEGAKARYOCYTIC; MEGAKARYOCYTIC/ERYTHROID HEMATOPOIESIS; MRI; STATIC MAGNETIC FIELDS; UMBILICAL CORD BLOOD;

SUPERCONDUCTING MAGNETS;

CARBON DIOXIDE; CD34 ANTIGEN; HELIUM;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; COLONY FORMATION; CONTROLLED STUDY; ERYTHROID CELL; GENE EXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATOR; MAGNETIC FIELD; MEGAKARYOCYTE; NUCLEAR MAGNETIC RESONANCE IMAGING; PLACENTA; PRIORITY JOURNAL; UMBILICAL CORD BLOOD; UPREGULATION; CYTOLOGY; ERYTHROID PRECURSOR CELL; FEMALE; FETUS BLOOD; GENE EXPRESSION PROFILING; MAGNETISM; RADIATION EXPOSURE; STEM CELL; VASCULARIZATION;

ANTIGENS, CD34; CELL DIFFERENTIATION; ERYTHROID PRECURSOR CELLS; FEMALE; FETAL BLOOD; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEMATOPOIESIS; HUMANS; MAGNETICS; MEGAKARYOCYTES; PLACENTA; STEM CELLS; UP-REGULATION;

EID: 66149138063     PISSN: 01978462     EISSN: 1521186X     Source Type: Journal    
DOI: 10.1002/bem.20480     Document Type: Article

References (32)

1. Brunet de la Grange P, Armstrong F, Duval V, Rouyez MC, Goardon N, Romeo PH, Pflumio F. 2006. Low SCL/TAL1 expression reveals its major role in adult hematopoietic myeloid progenitors and stem cells. Blood 108:2998-3004.
2. De Wilde JP, Rivers AW, Price DL. 2005. A review of the current use of magnetic resonance imaging in pregnancy and safety implications for the fetus. Prog Biophys Mol Biol 87:335-353.
3. Elwood NJ, ZogosH, Pereira DS, Dick JE, Begley CG. 1998. Enhanced megakaryocyte and erythroid development from normal human CD34() cells: Consequence of enforced expression of SCL. Blood 91:3756-3765.
4. Escribano L, Ocqueteau M, Almeida J, Orfao A, San Miguel JF. 1998. Expression of the c-kit (CD117) molecule in normal and malignant hematopoiesis. Leuk Lymphoma 30:459-466.
5. Feychting M. 2005. Health effects of static magnetic fields: A review of the epidemiological evidence. Prog Biophys Mol Bio 87: 241-246.
6. Hamimovitz-Friedman A. 1998. Radiation-induced signal transduction and stress response. Radiat Res 150:S102-S108.
7. ICNIRP. 2004. International Commission on Non-Ionizing Radiation Protection. Medical MR procedures, protection of patient, volunteer and staff. Health Phys. 2004. 87:197-216.
8. IEC 60601-2-33. 2002. Particular Requirements for the Safety of Magnetic Resonance Equipment for Medical Diagnosis. International Electrical Comission, Geneva, Switzerland.
9. Ikonomi P, Rivera CE, Riordan M, Washington G, Schechter AN, Noguchi CT. 2000. Overexpressionof GATA-2 inhibits erythroid and promotes megakaryocyte differentiation. Exp Hematol 28:1423-1431.
10. Kanal E, Gillen J, Evans JA, Savitz DA, Shellock FG. 1993. Survey on reproductive health among female MR workers. Radiology 187:395-399.
11. Kanal E, Borgstede JP, Barkovich AJ, Bell C, Bradley WG, Felmlee JP, Froelich JW, Kaminski EM, Keeler EK, Lester JW, Scoumis EA, Zaremba LA, Zinninger MD. American College of Radiology. 2002. American College of Radiology white paper on MR safety. Am J Radiol 178:1335-1347.
12. Kashiwakura I, Takahashi K, Takagaki K. 2007. Application of proteoglycan extracted from the nasal cartilage of salmon heads for ex vivo expansion of hematopoietic progenitor cells derived from human umbilical cord blood. Glycoconj J 24:251-258.
13. Kieffer I, Lorenzo C, Dozier C, Schmitt E, Ducommun B. 2007. Differential mitotic degradation of the CDC25B phosphatase variants. Oncogene 26:7847-7858.
14. Lecuyer E, Hoang T. 2004. SCL: From the origin of hematopoiesis to stem cells and leukemia. Exp Hematol 32:11-24.
15. Lulli V, Romania P, Morsilli O, Gabbianelli M, Pagliuca A, Mazzeo S, Testa U, Peschle C, Marziali G 2006. Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiation. Cell Death Differ 13:1064-1074.
16. Medical Devices Agency. 2002. Guidelines for Magnetic Resonance Diagnostic Equipment in Clinical Use. Medicines and Healthcare products Regulatory Agency, London.
17. Miyakoshi J. 2005. Effects of static magnetic fields at the cellular level. Prog Biophys Mol Biol 87:213-223.
18. Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Okada Y, Doi T. 2006. RUNX1 suppression induces megakaryocytic differentiation of UT-7/GM cells. Biochem Biophys Res Commun 345:78-84.
19. Nagayama H, Misawa K, Tanaka H, Ooi J, Iseki T, Tojo A, Tani K, Yamada Y, Kodo H, Takahashi TA, Yamashita N, Shimazaki S, Asano S. 2002. Transient hematopoietic stem cell rescue using umbilical cord blood for a lethally irradiated nuclear accident victim. Bone Marrow Transplant 29:197-204.
20. Nakahara T, Yaguchi H, Yoshida M, Miyakoshi J. 2002. Effects of exposure of CHO-K1 cells to a 10 T static magnetic field. Radiology 224:817-822.
21. Onodera H, Jin Z, Chida S, Suzuki Y, Tago H, Itoyama Y 2003. Effects of 10 T static magnetic field on human peripheral blood immune cells. Radiat Res 159:775-779.
22. Saito K, Suzuki H, Suzuki K. 2006. Teratogenic effects of static magnetic field on mouse fetuses. Reprod Toxicol 22:118-124.
23. Schmidt-Ullrich RK, Dent P, Grant S, Mikkelsen RB, Valerie K. 2000. Signal transduction and cellular radiation responses. Radiat Res 153:245-257.
24. Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R. 2007. Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm. J Magn Reson Imaging 26:279-287.
25. Takahashi W, Sasaki K, Komatsu N, Mitani K. 2005. TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT-7/GM. Cancer Sci 96:340-348.
26. Takahashi K, Monzen S, Eguchi-Kasai K, Abe Y, Kashiwakura I. 2007. Severe damage of human megakaryocytopoiesis and thrombopoiesis by heavy-ion beam radiation. Radiat Res 168: 545-551.
27. Tirasophon W, Welihinda AA, Kaufman RJ. 1998. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 12:1812-1824.
28. U. S. Radiological Health Bureau. 1982. Guidelines for evaluating electromagnetic exposure risk for trialsofclinical NMR systems. Rockville, MD: U. S. Food and Drug Administration.
29. Wiemels JL, Cazzaniga G, Daniotti M, Eden OB, Addison GM, Masera G, Saha V, Biondi A, Greaves MF. 1999. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 354: 1499-1503.
30. Wright EG. 1998. Radiation-induced genomic instability in haemopoietic cells. Int J Radiat Biol 74:681-687.
31. Zhang QM, Tokiwa M, Doi T, Nakahara T, Chang PW, Nakamura N, Hori M, Miyakoshi J, Yonei S. 2003. Strong static magnetic field and the induction of mutations through elevated production of reactive oxygen species in Escherichia coli sox R. Int J Radiat Biol 79:281-286.
32. Zhang Y, Payne KJ, Zhu Y, Price MA, Parrish YK, Zielinska E, Barsky LW, Crooks GM. 2005. SCL expression at critical points in human hematopoietic lineage commitment. Stem Cells 23: 852-860.