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Volumn 83, Issue 12, 2009, Pages 5987-5998

Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CELL DNA; HISTONE H2AX; MRE11 PROTEIN; PROTEIN SERINE THREONINE KINASE; VIRUS DNA; ATM PROTEIN; ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA DEPENDENT PROTEIN KINASE; H2AFX PROTEIN, HUMAN; HISTONE; MRE11A PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; TUMOR SUPPRESSOR PROTEIN;

EID: 66149137964     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00091-09     Document Type: Article
Times cited : (43)

References (64)
  • 1
    • 33646183367 scopus 로고    scopus 로고
    • DNA damage responses and their many interactions with the replication fork
    • Andreassen, P. R., G. P. Ho, and A. D. D'Andrea. 2006. DNA damage responses and their many interactions with the replication fork. Carcinogenesis 27:883-892.
    • (2006) Carcinogenesis , vol.27 , pp. 883-892
    • Andreassen, P.R.1    Ho, G.P.2    D'Andrea, A.D.3
  • 2
    • 23844438197 scopus 로고    scopus 로고
    • Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes
    • DOI 10.1128/JVI.79.17.11382-11391.2005
    • Araujo, F. D., T. H. Stracker, C. T. Carson, D. V. Lee, and M. D. Weitzman. 2005. Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes. J. Virol. 79:11382-11391. (Pubitemid 41170679)
    • (2005) Journal of Virology , vol.79 , Issue.17 , pp. 11382-11391
    • Araujo, F.D.1    Stracker, T.H.2    Carson, C.T.3    Lee, D.V.4    Weitzman, M.D.5
  • 3
    • 34250894884 scopus 로고    scopus 로고
    • Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation
    • DOI 10.1128/JVI.00029-07
    • Baker, A., K. J. Rohleder, L. A. Hanakahi, and G. Ketner. 2007. Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J. Virol. 81:7034-7040. (Pubitemid 46986639)
    • (2007) Journal of Virology , vol.81 , Issue.13 , pp. 7034-7040
    • Baker, A.1    Rohleder, K.J.2    Hanakahi, L.A.3    Ketner, G.4
  • 4
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • DOI 10.1038/nature01368
    • Bakkenist, C. J., and M. B. Kastan. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499-506. (Pubitemid 36168436)
    • (2003) Nature , vol.421 , Issue.6922 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 7
    • 0033604299 scopus 로고    scopus 로고
    • Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase
    • DOI 10.1006/viro.1999.9866
    • Boyer, J., K. Rohleder, and G. Ketner. 1999. Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase. Virology 263:307-312. (Pubitemid 29521523)
    • (1999) Virology , vol.263 , Issue.2 , pp. 307-312
    • Boyer, J.1    Rohleder, K.2    Ketner, G.3
  • 8
    • 0032982299 scopus 로고    scopus 로고
    • 2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection
    • 2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection. Gene Ther. 6:1054-1063.
    • (1999) Gene Ther. , vol.6 , pp. 1054-1063
    • Brand, K.1    Klocke, R.2    Possling, A.3    Paul, D.4    Strauss, M.5
  • 9
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma, S., B. P. Chen, M. Murphy, A. Kurimasa, and D. J. Chen. 2001. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276:42462-42467.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 14
    • 0042197119 scopus 로고    scopus 로고
    • Single-strand DNA gaps trigger an ATR and Cdc7-dependent checkpoint
    • Costanzo, V., and J. Gautier. 2003. Single-strand DNA gaps trigger an ATR and Cdc7-dependent checkpoint. Cell Cycle 2:17.
    • (2003) Cell Cycle , vol.2 , pp. 17
    • Costanzo, V.1    Gautier, J.2
  • 15
    • 0348014686 scopus 로고    scopus 로고
    • DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
    • DOI 10.1101/gad.1156903
    • Cuconati, A., C. Mukherjee, D. Perez, and E. White. 2003. DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells. Genes Dev. 17:2922-2932. (Pubitemid 37523156)
    • (2003) Genes and Development , vol.17 , Issue.23 , pp. 2922-2932
    • Cuconati, A.1    Mukherjee, C.2    Perez, D.3    White, E.4
  • 17
    • 0037404513 scopus 로고    scopus 로고
    • Distinct roles of the adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation
    • DOI 10.1128/JVI.77.9.5295-5304.2003
    • Evans, J. D., and P. Hearing. 2003. Distinct roles of the Adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. J. Virol. 77:5295-5304. (Pubitemid 36460943)
    • (2003) Journal of Virology , vol.77 , Issue.9 , pp. 5295-5304
    • Evans, J.D.1    Hearing, P.2
  • 18
    • 18144401244 scopus 로고    scopus 로고
    • Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication
    • DOI 10.1128/JVI.79.10.6207-6215.2005
    • Evans, J. D., and P. Hearing. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J. Virol. 79:6207-6215. (Pubitemid 40617225)
    • (2005) Journal of Virology , vol.79 , Issue.10 , pp. 6207-6215
    • Evans, J.D.1    Hearing, P.2
  • 20
    • 34447628045 scopus 로고    scopus 로고
    • Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes
    • DOI 10.1038/sj.onc.1210281, PII 1210281
    • Fleisig, H. B., N. I. Orazio, H. Liang, A. F. Tyler, H. P. Adams, M. D. Weitzman, and L. Nagarajan. 2007. Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes. Oncogene 26:4797-4805. (Pubitemid 47093172)
    • (2007) Oncogene , vol.26 , Issue.33 , pp. 4797-4805
    • Fleisig, H.B.1    Orazio, N.I.2    Liang, H.3    Tyler, A.F.4    Adams, H.P.5    Weitzman, M.D.6    Nagarajan, L.7
  • 21
    • 49549130237 scopus 로고
    • Characterization of single-stranded viral DNA sequences present during replication of adenovirus types 2 and 5
    • Flint, S. J., S. M. Berget, and P. A. Sharp. 1976. Characterization of single-stranded viral DNA sequences present during replication of adenovirus types 2 and 5. Cell 9:559-571.
    • (1976) Cell , vol.9 , pp. 559-571
    • Flint, S.J.1    Berget, S.M.2    Sharp, P.A.3
  • 22
    • 0031661313 scopus 로고    scopus 로고
    • E1B 55-kilodalton-associated protein: A cellular protein with RNA- Binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs
    • Gabler, S., H. Schutt, P. Groitl, H. Wolf, T. Shenk, and T. Dobner. 1998. E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs. J. Virol. 72:7960-7971. (Pubitemid 28421788)
    • (1998) Journal of Virology , vol.72 , Issue.10 , pp. 7960-7971
    • Gabler, S.1    Schutt, H.2    Groitl, P.3    Wolf, H.4    Shenk, T.5    Dobner, T.6
  • 23
    • 34547402402 scopus 로고    scopus 로고
    • Detection and quantitation of subgroup C adenovirus DNA in human tissue samples by real-time PCR
    • Garnett, C. T., C. I. Pao, and L. R. Gooding. 2007. Detection and quantitation of subgroup C adenovirus DNA in human tissue samples by real-time PCR. Methods Mol. Med. 130:193-204.
    • (2007) Methods Mol. Med. , vol.130 , pp. 193-204
    • Garnett, C.T.1    Pao, C.I.2    Gooding, L.R.3
  • 25
    • 0032168061 scopus 로고    scopus 로고
    • Trans E1 component requirements for maximal replication of E1-defective recombinant adenovirus
    • Goldsmith, K. T., L. D. Dion, D. T. Curiel, and R. I. Garver, Jr. 1998. trans E1 component requirements for maximal replication of E1-defective recombinant adenovirus. Virology 248:406-419.
    • (1998) Virology , vol.248 , pp. 406-419
    • Goldsmith, K.T.1    Dion, L.D.2    Curiel, D.T.3    Garver Jr., R.I.4
  • 26
    • 34948849733 scopus 로고    scopus 로고
    • Adenovirus DNA is detected at increased frequency in Guthrie cards from children who develop acute lymphoblastic leukaemia
    • DOI 10.1038/sj.bjc.6603983, PII 6603983
    • Gustafsson, B., W. Huang, G. Bogdanovic, F. Gauffin, A. Nordgren, G. Talekar, D. A. Ornelles, and L. R. Gooding. 2007. Adenovirus DNA is detected at increased frequency in Guthrie cards from children who develop acute lymphoblastic leukaemia. Br. J. Cancer 97:992-994. (Pubitemid 47519321)
    • (2007) British Journal of Cancer , vol.97 , Issue.7 , pp. 992-994
    • Gustafsson, B.1    Huang, W.2    Bogdanovic, G.3    Gauffin, F.4    Nordgren, A.5    Talekar, G.6    Ornelles, D.A.7    Gooding, L.R.8
  • 27
    • 0345708265 scopus 로고    scopus 로고
    • Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest
    • Hammond, E. M., S. L. Green, and A. J. Giaccia. 2003. Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest. Mutat. Res. 532:205-213.
    • (2003) Mutat. Res. , vol.532 , pp. 205-213
    • Hammond, E.M.1    Green, S.L.2    Giaccia, A.J.3
  • 28
    • 0036720983 scopus 로고    scopus 로고
    • Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery
    • DOI 10.1128/JVI.76.18.9194-9206.2002
    • Harada, J. N., A. Shevchenko, D. C. Pallas, and A. J. Berk. 2002. Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J. Virol. 76:9194-9206. (Pubitemid 34919878)
    • (2002) Journal of Virology , vol.76 , Issue.18 , pp. 9194-9206
    • Harada, J.N.1    Shevchenko, A.2    Shevchenko, A.3    Pallas, D.C.4    Berk, A.J.5
  • 29
    • 0024344731 scopus 로고
    • Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection
    • Huang, M. M., and P. Hearing. 1989. Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection. J. Virol. 63:2605-2615. (Pubitemid 19137537)
    • (1989) Journal of Virology , vol.63 , Issue.6 , pp. 2605-2615
    • Huang, M.-M.1    Hearing, P.2
  • 30
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan, M. B., and D. S. Lim. 2000. The many substrates and functions of ATM. Nat. Rev. Mol. Cell. Biol. 1:179-186.
    • (2000) Nat. Rev. Mol. Cell. Biol. , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 31
    • 14844336913 scopus 로고    scopus 로고
    • Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an Sphase-like cellular environment
    • Kudoh, A., M. Fujita, L. Zhang, N. Shirata, T. Daikoku, Y. Sugaya, H. Isomura, Y. Nishiyama, and T. Tsurumi. 2005. Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an Sphase-like cellular environment. J. Biol. Chem. 280:8156-8163.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8156-8163
    • Kudoh, A.1    Fujita, M.2    Zhang, L.3    Shirata, N.4    Daikoku, T.5    Sugaya, Y.6    Isomura, H.7    Nishiyama, Y.8    Tsurumi, T.9
  • 32
    • 0016748114 scopus 로고
    • Isolation and partial characterization of single-stranded adenoviral DNA produced during synthesis of adenovirus type 2 DNA
    • Lavelle, G., C. Patch, G. Khoury, and J. Rose. 1975. Isolation and partial characterization of single-stranded adenoviral DNA produced during synthesis of adenovirus type 2 DNA. J. Virol. 16:775-782.
    • (1975) J. Virol. , vol.16 , pp. 775-782
    • Lavelle, G.1    Patch, C.2    Khoury, G.3    Rose, J.4
  • 33
    • 0031912083 scopus 로고    scopus 로고
    • Adenovirus endocytosis via alpha (v) integrins requires phosphoinositide-3-OH kinase
    • Li, E., D. Stupack, R. Klemke, D. A. Cheresh, and G. R. Nemerow. 1998. Adenovirus endocytosis via alpha (v) integrins requires phosphoinositide-3-OH kinase. J. Virol. 72:2055-2061.
    • (1998) J. Virol. , vol.72 , pp. 2055-2061
    • Li, E.1    Stupack, D.2    Klemke, R.3    Cheresh, D.A.4    Nemerow, G.R.5
  • 34
  • 35
    • 27644504904 scopus 로고    scopus 로고
    • Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex
    • DOI 10.1128/JVI.79.22.14004-14016.2005
    • Liu, Y., A. Shevchenko, and A. J. Berk. 2005. Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex. J. Virol. 79:14004-14016. (Pubitemid 41552699)
    • (2005) Journal of Virology , vol.79 , Issue.22 , pp. 14004-14016
    • Liu, Y.1    Shevchenko, A.2    Shevchenko, A.3    Berk, A.J.4
  • 37
    • 41649088194 scopus 로고    scopus 로고
    • Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication
    • Mathew, S. S., and E. Bridge. 2008. Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication. Virology 374:11-22.
    • (2008) Virology , vol.374 , pp. 11-22
    • Mathew, S.S.1    Bridge, E.2
  • 38
    • 34547686371 scopus 로고    scopus 로고
    • The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication
    • DOI 10.1016/j.virol.2007.03.049, PII S0042682207001924
    • Mathew, S. S., and E. Bridge. 2007. The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication. Virology 365:346-355. (Pubitemid 47223307)
    • (2007) Virology , vol.365 , Issue.2 , pp. 346-355
    • Mathew, S.S.1    Bridge, E.2
  • 39
    • 35748973572 scopus 로고    scopus 로고
    • Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival
    • Miller, D. L., C. L. Myers, B. Rickards, H. A. Coller, and S. J. Flint. 2007. Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival. Genome Biol. 8:R58.
    • (2007) Genome Biol. , vol.8
    • Miller, D.L.1    Myers, C.L.2    Rickards, B.3    Coller, H.A.4    Flint, S.J.5
  • 40
    • 0026028434 scopus 로고
    • Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: Association with nuclear viral inclusions requires the early region 4 34-kilodalton protein
    • Ornelles, D. A., and T. Shenk. 1991. Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein. J. Virol. 65:424-429.
    • (1991) J. Virol. , vol.65 , pp. 424-429
    • Ornelles, D.A.1    Shenk, T.2
  • 41
    • 0344237360 scopus 로고    scopus 로고
    • DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner
    • DOI 10.1093/nar/gkg921
    • Park, E. J., D. W. Chan, J. H. Park, M. A. Oettinger, and J. Kwon. 2003. DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner. Nucleic Acids Res. 31: 6819-6827. (Pubitemid 37508789)
    • (2003) Nucleic Acids Research , vol.31 , Issue.23 , pp. 6819-6827
    • Park, E.-J.1    Chan, D.W.2    Park, J.-H.3    Oettinger, M.A.4    Kwon, J.5
  • 42
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull, T. T., E. P. Rogakou, V. Yamazaki, C. U. Kirchgessner, M. Gellert, and W. M. Bonner. 2000. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10:886-895.
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 44
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou, E. P., D. R. Pilch, A. H. Orr, V. S. Ivanova, and W. M. Bonner. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 45
  • 46
    • 0032189483 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
    • Sarkaria, J. N., R. S. Tibbetts, E. C. Busby, A. P. Kennedy, D. E. Hill, and R. T. Abraham. 1998. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res. 58:4375-4382. (Pubitemid 28450040)
    • (1998) Cancer Research , vol.58 , Issue.19 , pp. 4375-4382
    • Sarkaria, J.N.1    Tibbetts, R.S.2    Busby, E.C.3    Kennedy, A.P.4    Hill, D.E.5    Abraham, R.T.6
  • 47
    • 31144477390 scopus 로고    scopus 로고
    • Adenovirus vectors deleted for genes essential for viral DNA replication
    • Schaack, J. 2005. Adenovirus vectors deleted for genes essential for viral DNA replication. Front. Biosci. 10:1146-1155.
    • (2005) Front. Biosci. , vol.10 , pp. 1146-1155
    • Schaack, J.1
  • 48
    • 0000557447 scopus 로고    scopus 로고
    • Adenoviridae: The viruses and their replication
    • B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Lippincott-Raven Publishers, Philadelphia, PA
    • Shenk, T. 1996. Adenoviridae: the viruses and their replication, p. 2111-2148. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, PA.
    • (1996) Fields Virology, 3rd Ed. , pp. 2111-2148
    • Shenk, T.1
  • 49
    • 0034284157 scopus 로고    scopus 로고
    • DNA replication of first-generation adenovirus vectors in tumor cells
    • Steinwaerder, D. S., C. A. Carlson, and A. Lieber. 2000. DNA replication of first-generation adenovirus vectors in tumor cells. Hum. Gene Ther. 11:1933-1948.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 1933-1948
    • Steinwaerder, D.S.1    Carlson, C.A.2    Lieber, A.3
  • 50
    • 0037468192 scopus 로고    scopus 로고
    • MDC1 is a mediator of the mammalian DNA damage checkpoint
    • DOI 10.1038/nature01446
    • Stewart, G. S., B. Wang, C. R. Bignell, A. M. Taylor, and S. J. Elledge. 2003. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421:961-966. (Pubitemid 36288029)
    • (2003) Nature , vol.421 , Issue.6926 , pp. 961-966
    • Stewart, G.S.1    Wang, B.2    Bigneli, C.R.3    Taylor, A.M.R.4    Elledge, S.J.5
  • 51
    • 0037130170 scopus 로고    scopus 로고
    • Adenovirus oncoproteins inactivate the Mre11-Rad50-NBs1 DNA repair complex
    • DOI 10.1038/nature00863
    • Stracker, T. H., C. T. Carson, and M. D. Weitzman. 2002. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348-352. (Pubitemid 34790688)
    • (2002) Nature , vol.418 , Issue.6895 , pp. 348-352
    • Stracker, T.H.1    Carson, C.T.2    Weilzman, M.D.3
  • 52
    • 18744362169 scopus 로고    scopus 로고
    • Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins
    • DOI 10.1128/JVI.79.11.6664-6673.2005
    • Stracker, T. H., D. V. Lee, C. T. Carson, F. D. Araujo, D. A. Ornelles, and M. D. Weitzman. 2005. Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins. J. Virol. 79:6664-6673. (Pubitemid 40677297)
    • (2005) Journal of Virology , vol.79 , Issue.11 , pp. 6664-6673
    • Stracker, T.H.1    Lee, D.V.2    Carson, C.T.3    Araujo, F.D.4    Ornelles, D.A.5    Weitzman, M.D.6
  • 53
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • DOI 10.1016/j.cell.2005.09.038, PII S0092867405011657
    • Stucki, M., J. A. Clapperton, D. Mohammad, M. B. Yaffe, S. J. Smerdon, and S. P. Jackson. 2005. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123:1213-1226. (Pubitemid 41821780)
    • (2005) Cell , vol.123 , Issue.7 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 54
    • 33646106590 scopus 로고    scopus 로고
    • GammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
    • Stucki, M., and S. P. Jackson. 2006. gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. DNA Repair 5:534-543.
    • (2006) DNA Repair , vol.5 , pp. 534-543
    • Stucki, M.1    Jackson, S.P.2
  • 57
    • 11144305946 scopus 로고    scopus 로고
    • Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
    • DOI 10.1002/jcp.20141
    • Wang, H., M. Wang, W. Bocker, and G. Iliakis. 2005. Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. J. Cell Physiol. 202:492-502. (Pubitemid 40041320)
    • (2005) Journal of Cellular Physiology , vol.202 , Issue.2 , pp. 492-502
    • Wang, H.1    Wang, M.2    Wang, H.3    Bocker, W.4    Iliakis, G.5
  • 58
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward, I. M., and J. Chen. 2001. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem. 276:47759-47762.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 59
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
    • Ward, I. M., K. Minn, K. G. Jorda, and J. Chen. 2003. Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J. Biol. Chem. 278:19579-19582.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19579-19582
    • Ward, I.M.1    Minn, K.2    Jorda, K.G.3    Chen, J.4
  • 60
    • 3242887430 scopus 로고    scopus 로고
    • Interactions of viruses with the cellular DNA repair machinery
    • DOI 10.1016/j.dnarep.2004.03.018, PII S1568786404000771
    • Weitzman, M. D., C. T. Carson, R. A. Schwartz, and C. E. Lilley. 2004. Interactions of viruses with the cellular DNA repair machinery. DNA Repair 3:1165-1173. (Pubitemid 38997960)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 1165-1173
    • Weitzman, M.D.1    Carson, C.T.2    Schwartz, R.A.3    Lilley, C.E.4
  • 61
    • 10944219768 scopus 로고    scopus 로고
    • Control of sister chromatid recombination by histone H2AX
    • DOI 10.1016/j.molcel.2004.12.007, PII S1097276504007543
    • Xie, A., N. Puget, I. Shim, S. Odate, I. Jarzyna, C. H. Bassing, F. W. Alt, and R. Scully. 2004. Control of sister chromatid recombination by histone H2AX. Mol. Cell 16:1017-1025. (Pubitemid 40018410)
    • (2004) Molecular Cell , vol.16 , Issue.6 , pp. 1017-1025
    • Xie, A.1    Puget, N.2    Shim, I.3    Odate, S.4    Jarzyna, I.5    Bassing, C.H.6    Alt, F.W.7    Scully, R.8
  • 62
    • 0142154314 scopus 로고    scopus 로고
    • ATM, ATR and DNA-PK: Initiators of the cellular genotoxic stress responses
    • DOI 10.1093/carcin/bgg137
    • Yang, J., Y. Yu, H. E. Hamrick, and P. J. Duerksen-Hughes. 2003. ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses. Carcinogenesis 24:1571-1580. (Pubitemid 37304662)
    • (2003) Carcinogenesis , vol.24 , Issue.10 , pp. 1571-1580
    • Yang, J.1    Yu, Y.2    Hamrick, H.E.3    Duerksen-Hughes, P.J.4
  • 63
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • DOI 10.1126/science.1083430
    • Zou, L., and S. J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300:1542-1548. (Pubitemid 36682880)
    • (2003) Science , vol.300 , Issue.5625 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 64
    • 33745607897 scopus 로고    scopus 로고
    • Functions of human replication protein a (RPA): From DNA replication to DNA damage and stress responses
    • DOI 10.1002/jcp.20622
    • Zou, Y., Y. Liu, X. Wu, and S. M. Shell. 2006. Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses. J. Cell Physiol. 208:267-273. (Pubitemid 43993416)
    • (2006) Journal of Cellular Physiology , vol.208 , Issue.2 , pp. 267-273
    • Zou, Y.1    Liu, Y.2    Wu, X.3    Shell, S.M.4


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