Optimized antidepressant therapy and pain self-management in primary care patients with depression and musculoskeletal pain: A randomized controlled trial

JAMA

Volumn 301, Issue 20, 2009, Pages 2099-2110

  Kroenke, Kurt ^a,b   Bair, Matthew J ^a,b,c   Damush, Teresa M ^a,b,c   Wu, Jingwei ^b   Hoke, Shawn ^a,c   Sutherland, Jason ^d   Tu, Wanzhu ^a,b  

^a REGENSTRIEF INSTITUTE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d DARTMOUTH INSTITUTE FOR HEALTH POLICY AND CLINICAL PRACTICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ANALGESIC AGENT; ANTIDEPRESSANT AGENT; CITALOPRAM; FLUOXETINE; MIRTAZAPINE; NARCOTIC ANALGESIC AGENT; NORTRIPTYLINE; OPIATE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

ADULT; AGED; ARTICLE; BRIEF PAIN INVENTORY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEALTH CARE COST; HIP PAIN; HUMAN; KNEE PAIN; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MUSCULOSKELETAL PAIN; PHYSICAL DISABILITY; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SELF CARE; TREATMENT OUTCOME; UNITED STATES; CHRONIC DISEASE; COGNITIVE THERAPY; COMORBIDITY; HIP; KNEE; MAJOR DEPRESSION; MIDDLE AGED; PAIN; PAIN ASSESSMENT; PRIMARY HEALTH CARE; PSYCHOLOGICAL RATING SCALE;

ADULT; AGED; ANTIDEPRESSIVE AGENTS; CHRONIC DISEASE; COGNITIVE THERAPY; COMORBIDITY; DEPRESSIVE DISORDER, MAJOR; FEMALE; HIP JOINT; HUMANS; KNEE JOINT; LOW BACK PAIN; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; PRIMARY HEALTH CARE; PSYCHIATRIC STATUS RATING SCALES; SELF CARE;

EID: 66149136454     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2009.723     Document Type: Article

References (69)

1. Kroenke K. Patients presenting with somatic complaints: epidemiology, psychiatric comorbidity and management. Int J Methods Psychiatr Res. 2003; 12(1):34-43. (Pubitemid 36675446)
2. Spitzer RL, Kroenke K, Linzer M, et al. Health-related quality of life in primary care patients with mental disorders: results from the PRIME-MD 1000 study. JAMA. 1995;274(19):1511-1517.
3. Schappert SM. National Ambulatory Medical Care Survey: 1989 summary. Vital Health Stat 13. 1992; 13(110):10-11.
4. Sternbach RA. Survey of pain in the United States: the Nuprin Pain Report. Clin J Pain. 1986;2:49-53. (Pubitemid 17188450)
5. Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch Intern Med. 2003;163(20):2433-2445. (Pubitemid 37385786)
6. Jackson JL, O'Malley PG, Kroenke K. Antidepressants and cognitive-behavioral therapy for symptom syndromes. CNS Spectr. 2006;11(3):212-222.
7. Kroenke K, Krebs EE, Bair MJ. Pharmacotherapy of chronic pain: a synthesis of recommendations from systematic reviews. Gen Hosp Psychiatry. In press.
8. Lorig K. Self-management education: more than a nice extra. Med Care. 2003;41(6):699-701.
9. Von Korff M, Moore JC. Stepped care for back pain: activating approaches for primary care. Ann Intern Med. 2001;134(9 pt 2):911-917. (Pubitemid 32405700)
10. Lorig KR, Holman H. Self-management education: history, definition, outcomes, and mechanisms. Ann Behav Med. 2003;26(1):1-7. (Pubitemid 36950984)
11. Damush TM, Weinberger M, Perkins SM, et al. Randomized trial of a self-management program for primary care patients with acute low back pain: short-term effects. Arthritis Rheum. 2003;49(2):179-186. (Pubitemid 36418275)
12. Pariser D, O'Hanlon A. Effects of telephone intervention on arthritis self-efficacy, depression, pain, and fatigue in older adults with arthritis. J Geriatr Phys Ther. 2005;28(3):67-73.
13. Warsi A, LaValley MP, Wang PS, Avorn J, Solomon DH. Arthritis self-management education programs: a meta-analysis of the effect on pain and disability. Arthritis Rheum. 2003;48(8):2207-2213. (Pubitemid 36959201)
14. Chodosh J, Morton SC, Mojica W, et al. Metaanalysis: chronic disease self-management programs for older adults. Ann Intern Med. 2005;143(6): 427-438. (Pubitemid 41338940)
15. Newman S, Steed L, Mulligan K. Self-management interventions for chronic illness. Lancet. 2004;364 (9444):1523-1537. (Pubitemid 39410420)
16. Holman HR, Lorig K. Self-management education for osteoarthritis. Ann Intern Med. 2006;144 (8):617. (Pubitemid 46768152)
17. Kroenke K, Bair M, Damush T, et al. Stepped Care for Affective Disorders and Musculoskeletal Pain (SCAMP) study design and practical implications of an intervention for comorbid pain and depression. Gen Hosp Psychiatry. 2007;29(6):506-517. (Pubitemid 350088162)
18. Cleeland CS. Measurement of pain by subjective report. In: Chapman CR, Loeser JD, eds. Advances in Pain Research and Therapy, Volume 12: Issues in Pain Measurement. New York, NY: Raven Press; 1989: 391-403.
19. Williams LS, Jones WJ, Shen J, Robinson RL, Weinberger M, Kroenke K. Prevalence and impact of depression and pain in neurology outpatients. J Neurol Neurosurg Psychiatry. 2003;74(11):1587-1589. (Pubitemid 41665012)
20. Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606-613. (Pubitemid 32823891)
21. Kroenke K, West SL, Swindle R, et al. Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial. JAMA. 2001; 286(23):2947-2955. (Pubitemid 33140358)
22. Unützer J, Katon W, Callahan CM, et al; IMPACT Investigators. Collaborative care management of latelife depression in the primary care setting: a randomized controlled trial. JAMA. 2002;288(22):2836-2845. (Pubitemid 35425069)
23. Dietrich AJ, Oxman TE, Williams JW Jr, et al. Reengineering systems for the treatment of depression in primary care: cluster randomised controlled trial. BMJ. 2004;329(7466):602-605. (Pubitemid 39256546)
24. Spitzer RL, Williams JB, Kroenke K, et al. Utility of a new procedure for diagnosing mental disorders in primary care: the PRIME-MD 1000 study. JAMA. 1994;272(22):1749-1756. (Pubitemid 24372002)
25. Löwe B, Unutzer J, Callahan CM, Perkins AJ, Kroenke K. Monitoring depression treatment outcomes with the Patient Health Questionnaire-9. Med Care. 2004;42(12):1194-1201. (Pubitemid 39627296)
26. Katon W, Von Korff M, Lin E, et al. Stepped collaborative care for primary care patients with persistent symptoms of depression: a randomized trial. Arch Gen Psychiatry. 1999;56(12):1109-1115.
27. Williams JW Jr, Barrett J, Oxman T, et al. Treatment of dysthymia and minor depression in primary care: a randomized controlled trial in older adults. JAMA. 2000;284(12):1519-1526.
28. Dworkin RH, Turk DC, Farrar JT, et al; IMMPACT. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113 (1-2):9-19. (Pubitemid 40038441)
29. Cleeland CS, Gonin R, Hatfield AK, et al. Pain and its treatment in outpatients with metastatic cancer. N Engl J Med. 1994;330(9):592-596. (Pubitemid 24065792)
30. Von Korff M, Ormel J, Keefe FJ, Dworkin SF. Grading the severity of chronic pain. Pain. 1992;50 (2):133-149.
31. Roland M, Morris R. A study of the natural history of back pain, part I: development of a reliable and sensitive measure of disability in low-back pain. Spine. 1983;8(2):141-144.
32. Jensen MP, Strom SE, Turner JA, Romano JM. Validity of the Sickness Impact Profile Roland scale as a measure of dysfunction in chronic pain patients. Pain. 1992;50(2):157-162.
33. McHorney CA, Ware JE Jr, Raczek AE. The MOS 36-Item Short-Form Health Survey (SF-36), II: psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 1993; 31(3):247-263.
34. Ware JE Jr, Gandek B; IQOLA Project Group. The SF-36 Health Survey: development and use in mental health research and the IQOLA Project. Int J Ment Health. 1994;23(2)):49-73.
35. Idler EL, Benyamini Y. Self-rated health and mortality: a review of twenty-seven community studies. J Health Soc Behav. 1997;38(1):21-37. (Pubitemid 127454450)
36. Spitzer RL, Kroenke K, Williams JB, Lowe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092- 1097. (Pubitemid 43765180)
37. Kroenke K, Spitzer RL, Williams JBW, Monahan PO, Lowe B. Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Ann Intern Med. 2007;146(5):317-325.
38. Cintron A, Morrison RS. Pain and ethnicity in the United States: a systematic review. J Palliat Med. 2006; 9(6):1454-1473. (Pubitemid 46047954)
39. Williams JW Jr, Gerrity M, Holsinger T, Dobscha S, Gaynes B, Dietrich A. Systematic review of multifaceted interventions to improve depression care. Gen Hosp Psychiatry. 2007;29(2):91-116. (Pubitemid 46320683)
40. Rush AJ, Trivedi MH, Wisniewski SR, et al; STAR*D Study Team. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. N Engl J Med. 2006;354(12):1231-1242.
41. Trivedi MH, Fava M, Wisniewski SR, et al; STAR*D Study Team. Medication augmentation after the failure of SSRIs for depression. N Engl J Med. 2006; 354(12):1243-1252.
42. Kroenke K, Spitzer RL. The PHQ-9: a new depression and diagnostic severity measure. Psychiatr Ann. 2002;32(9):509-515. (Pubitemid 37346793)
43. Lorig K, Holman H. Arthritis self-management studies: a twelve-year review. Health Educ Q. 1993; 20(1):17-28.
44. Bandura A. Social Foundations of Thought and Action: A Social Cognitive Theory. Englewood Cliffs, NJ: Prentice Hall; 1986.
45. Damush TM, Weinberger M, Perkins SM, et al. The long-term effects of a self-management program for inner-city, primary care patients with acute low back pain. Arch Intern Med. 2003;163(21): 2632-2638. (Pubitemid 37464422)
46. Damush TM, Weinberger M, Clark DO, et al. Acute low back pain self-management intervention for urban primary care patients: rationale, design, and predictors of participation. Arthritis Rheum. 2002; 47(4):372-379.
47. Keller MB. Past, present, and future directions for defining optimal treatment outcome in depression: remission and beyond. JAMA. 2003;289(23):3152-3160. (Pubitemid 37432891)
48. Dworkin RH, Turk DC, Wyrwich KW, et al. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. J Pain. 2008;9(2):105-121.
49. Zhang J, Yu KF. What's the relative risk? a method of correcting the odds ratio in cohort studies of common outcomes. JAMA. 1998;280:1690-1691. (Pubitemid 28532993)
50. Herbert RD. How to estimate treatment effects from reports of clinical trials, II: dichotomous outcomes. Aust J Physiother. 2000;46(4):309-313. (Pubitemid 32000355)
51. Gill D, Hatcher S. Antidepressants for depression in medical illness. Cochrane Database Syst Rev. 2000; (4):CD001312.
52. Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006;163(11):1905-1917. (Pubitemid 44807782)
53. Farrar JT, Portenoy RK, Berlin JA, Kinman JL, Strom BL. Defining the clinically important difference in pain outcome measures. Pain. 2000;88(3):287-294. (Pubitemid 30395253)
54. Gilbody S, Bower P, Fletcher J, Richards D, Sutton AJ. Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes. Arch Intern Med. 2006;166(21):2314-2321. (Pubitemid 44833355)
55. Thielke SM, Fan MY, Sullivan M, Unutzer J. Pain limits the effectiveness of collaborative care for depression. Am J Geriatr Psychiatry. 2007;15(8): 699-707. (Pubitemid 46322240)
56. Kroenke K, Shen J, Oxman TE, Williams JW Jr, Dietrich AJ. Impact of pain on the outcomes of depression treatment: results from the RESPECT trial. Pain. 2008;134(1-2):209-215. (Pubitemid 350251018)
57. Lin EH, Katon W, Von Korff M, et al; IMPACT Investigators. Effect of improving depression care on pain and functional outcomes among older adults with arthritis: a randomized controlled trial. JAMA. 2003; 290(18):2428-2429. (Pubitemid 37430542)
58. Dobscha SK, Corson K, Perrin NA, et al. Collaborative care for chronic pain in primary care: a clustered randomized trial. JAMA. 2009;301(12):1242- 1252.
59. Stewart WF, Ricci JA, Chee E, Hahn SR, Morganstein D. Cost of lost productive work time among US workers with depression. JAMA. 2003;289(23):3135-3144. (Pubitemid 37432889)
60. Stewart WF, Ricci JA, Chee E, Morganstein D, Lipton R. Lost productive time and cost due to common pain conditions in the US workforce. JAMA. 2003; 290(18):2443-2454. (Pubitemid 37430544)
61. Jung AC, Staiger T, Sullivan M. The efficacy of selective serotonin reuptake inhibitors for the management of chronic pain. J Gen Intern Med. 1997; 12(6):384-389. (Pubitemid 27255393)
62. Lynch ME. Antidepressants as analgesics: a review of randomized controlled trials. J Psychiatry Neurosci. 2001;26(1):30-36. (Pubitemid 32185177)
63. Krebs EE, Gaynes BN, Gartlehner G, et al. Treating the physical symptoms of depression with second-generation antidepressants: a systematic review and meta-analysis. Psychosomatics. 2008;49(3):191-198.
64. Rubenstein LV. Improving care for depression: there's no free lunch. Ann Intern Med. 2006;145 (7):544-546. (Pubitemid 46780958)
65. Callahan CM. Depression in primary care: encouragement and caution for the business case. J Gen Intern Med. 2006;21(10):1125-1127. (Pubitemid 44337748)
66. Katon WJ, Schoenbaum M, Fan MY, et al. Cost-effectiveness of improving primary care treatment of late-life depression. Arch Gen Psychiatry. 2005; 62(12):1313-1320. (Pubitemid 41746609)
67. Unutzer J, Katon WJ, Fan MY, et al. Long-term cost effects of collaborative care for late-life depression. Am J Manag Care. 2008;14(2):95-100.
68. Kroenke K, Swindle R. Cognitive-behavioral therapy for somatization and symptom syndromes: a critical review of controlled clinical trials. Psychother Psychosom. 2000;69(4):205-215. (Pubitemid 30413214)
69. Wang PS, Simon GE, Avorn J, et al. Telephone screening, outreach, and care management for depressed workers and impact on clinical and work productivity outcomes: a randomized controlled trial. JAMA. 2007;298(12):1401- 1411. (Pubitemid 47481606)