False-photosensitivity and transient hemiparesis following high-dose intravenous and intrathecal methotrexate for treatment of acute lymphoblastic leukemia

Pediatric Blood and Cancer

Volumn 53, Issue 1, 2009, Pages 103-105

  Shah, Nilay ^a   Zambidis, Elias T ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute lymphoblastic leukemia; Encephalopathy; False photosensitivity; Methotrexate

Indexed keywords

METHOTREXATE; VINCRISTINE; NUCLEIC ACID SYNTHESIS INHIBITOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ANAMNESIS; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CLINICAL FEATURE; DRUG MEGADOSE; DRUG WITHDRAWAL; HEMIPARESIS; HUMAN; LABORATORY TEST; MALE; MULTIPLE CYCLE TREATMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTOSENSITIVITY; PRIORITY JOURNAL; SUN EXPOSURE; CHEMICALLY INDUCED DISORDER; DYSARTHRIA; INTRASPINAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LABORATORY DIAGNOSIS; PARESIS; PHOTOSENSITIVITY DISORDER; RECURRENT DISEASE;

ADOLESCENT; DYSARTHRIA; FALSE POSITIVE REACTIONS; HUMANS; INJECTIONS, INTRAVENOUS; INJECTIONS, SPINAL; MALE; METHOTREXATE; NUCLEIC ACID SYNTHESIS INHIBITORS; PARESIS; PHOTOSENSITIVITY DISORDERS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE;

EID: 66149135648     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.21896     Document Type: Article

References (13)

1. Van Scott E. Folic acid antagonists affects on the cell and the patient. Ann Intern Med 1963;59:945.
2. Bell R, Sullivan JR, Burdon JG, et al. Toxic rash associated with high dose methotrexate therapy. Clin Exp Pharmacol Physiol 1979;5:57-61.
3. Neiman RA, Fye KH. Methotrexate induced false photosensitivity reaction. J Rheumatol 1985;12:354-355. (Pubitemid 15025382)
4. Westwick TJ, Sherertz EF, McCarley D, et al. Delayed reactivation of sunburn by methotrexate: Sparing of chronically sun-exposed skin. Cutis 1987;39:49-51. (Pubitemid 17002030)
5. Goerttler E, Kutzner H, Peter HH, et al. Methotrexate-induced papular eruption in patients with rheumatic diseases: A distinctive adverse cutaneous reaction produced by methotrexate in patients with collagen vascular diseases. J Am Acad Dermatol 1999;40:702-707. (Pubitemid 29230356)
6. Khan AJ, Marghoob AA, Prestia AE, et al. Methotrexate and the Photodermatitis reactivation reaction: A case report and review of the literature. Cutis 2000;66:379-382.
7. Walker RW, Allen JC, Rosen G, et al. Transient cerebral dysfunction secondary to high-dose methotrexate. J Clin Oncol 1986;4:1845-1850. (Pubitemid 17226676)
8. Yim YS, Mahoney DH, Jr., Oshman DG. Hemiparesis and ischemic changes of the white matter after intrathecal therapy for children with acute lymphocytic leukemia. Cancer 1991;67:2058-2061.
9. Inaba H, Khan RB, Laningham FH, et al. Clinical and radiological characteristics of methotrexate-induced acute encephalopathy in pediatric patients with cancer. Ann Oncol 2008;19:178-181.
10. Rollins N, Winick N, Bash R, et al. Acute methotrexate neurotoxicity: Findings on diffusion-weighted imaging and correlation with clinical outcome. Am J Neuroradiol 2004;25:1688-1695. (Pubitemid 44123692)
11. Boente Mdel C, Bibas Bonet H, Prime NB. Dermatopathy associated with levamisole-induced reversible posterior leukoencephalopathy. Arch Argent Pediatr 2008;106:42-46.
12. Hourani R, Abboud M, Hourani M, et al. L-asparaginase-induced posterior reversible encephalopathy syndrome during acute lymphoblastic leukemia treatment in children. Neuropediatrics 2008;39:46-50. (Pubitemid 351828318)
13. Min L, Zwerling J, Ocava LC, et al. Reversible posterior leukoencephalopathy in connective tissue diseases. Semin Arthritis Rheum 2006;35:388-395. (Pubitemid 43841894)