Structural characterization of the bradyzoite surface antigen (BSR4) from Toxoplasma gondii, a unique addition to the surface antigen glycoprotein 1-related superfamily

Journal of Biological Chemistry

Volumn 284, Issue 14, 2009, Pages 9192-9198

  Crawford, Joanna ^a   Grujic, Ognjen ^a   Bruic, Ekaterina ^a   Czjzek, Mirjam ^b   Grigg, Michael E ^c   Boulanger, Martin J ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b STATION BIOLOGIQUE DE ROSCOFF   (France)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; CHRONIC INFECTION; COMPLEX LIFE; DIMER FORMATION; DUAL ROLE; HOST CELLS; HUMAN POPULATION; INTER-DOMAIN; LIGAND BINDING; LIGAND-BINDING SITES; N-TERMINAL DOMAINS; PARASITE-; PHYSIOLOGICAL LIGANDS; PROTOZOAN PARASITES; SMALL ANGLE X-RAY SCATTERING; SOLUTION STRUCTURES; STRUCTURAL ADAPTATION; STRUCTURAL CHARACTERIZATION; STRUCTURAL DIVERSITY; SURFACE ANTIGEN; TOXOPLASMA GONDII; VIRULENCE FACTORS;

ANTIGENS; BINDING ENERGY; BINDING SITES; CRYSTAL STRUCTURE; GLYCOPROTEINS; INTERACTIVE COMPUTER SYSTEMS; LIGANDS; SCATTERING; STIMULATED RAMAN SCATTERING; X RAY SCATTERING;

X RAY CRYSTALLOGRAPHY;

ADHESIN; DIMER; MEMBRANE ANTIGEN; PROTEIN BSR4; SURFACE ANTIGEN GLYCOPROTEIN 1; UNCLASSIFIED DRUG; LIGAND; PARASITE ANTIGEN;

AMINO TERMINAL SEQUENCE; ARTICLE; BRADYZOITE; CRYSTAL STRUCTURE; CRYSTALLIZATION; LIGAND BINDING; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RADIATION SCATTERING; TOXOPLASMA GONDII; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; TOXOPLASMA;

PROTOZOA; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; TOXOPLASMA;

EID: 66149122633     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808714200     Document Type: Article

References (44)

1. Jackson, M. H., and Hutchison, W. M. (1989) Adv. Parasitol. 28, 55-105
2. McCabe, R. E., and Remington, J. S. (1983) Eur. J. Clin. Microbiol. 2, 95-104
3. Tenter, A. M., Heckeroth, A. R., and Weiss, L. M. (2000) Int. J. Parasitol. 30, 1217-1258
4. Luft, B. J., Brooks, R. G., Conley, F. K., McCabe, R. E., and Remington, J. S. (1984) J. Am. Med. Assoc. 252, 913-917
5. Luft, B. J., and Remington, J. S. (1992) Clin. Infect. Dis. 15, 211-222
6. McDonald, J. C., Gyorkos, T. W., Alberton, B., MacLean, J. D., Richer, G., and Juranek, D. (1990) J. Infect. Dis. 161, 769-774
7. Nussenblatt, R. B., and Belfort, R., Jr. (1994) J. Am. Med. Assoc. 271, 304-307
8. Silveira, C., Belfort, R., Jr., Burnier, M., Jr., and Nussenblatt, R. (1988) Am. J. Ophthalmol. 106, 362-364
9. Grigg, M., Ganatra, J., Boothroyd, J., and Margolis, T. (2001) J. Infect. Dis. 184, 633-639
10. Dubey, J. P. (1998) Int. J. Parasitol. 28, 1019-1024
11. Carruthers, V., and Boothroyd, J. C. (2007) Curr. Opin. Microbiol. 10, 83-89
12. Jung, C., Lee, C. Y., and Grigg, M. E. (2004) Int. J. Parasitol. 34, 285-296
13. Boothroyd, J. C., Hehl, A., Knoll, L. J., and Manger, I. D. (1998) Int. J. Parasitol. 28, 3-9
14. Cesbron-Delauw, M. F., Tomavo, S., Beauchamps, P., Fourmaux, M. P., Camus, D., Capron, A., and Dubremetz, J. F. (1994) J. Biol. Chem. 269, 16217-16222
15. Lekutis, C., Ferguson, D. J., and Boothroyd, J. C. (2000) Exp. Parasitol. 96, 89-96
16. Barragan, A., and Sibley, L. D. (2002) J. Exp. Med. 195, 1625-1633
17. Lekutis, C., Ferguson, D. J., Grigg, M. E., Camps, M., and Boothroyd, J. C. (2001) Int. J. Parasitol. 31, 1285-1292
18. Graille, M., Stura, E. A., Bossus, M., Muller, B. H., Letourneur, O., Battail-Poirot, N., Sibaï, G., Gauthier, M., Rolland, D., M. H., Le Du, M. H., and Ducancel, F. (2005) J. Mol. Biol. 354, 447-458
19. He, X. L., Grigg, M. E., Boothroyd, J. C., and Garcia, K. C. (2002) Nat. Struct. Biol. 9, 606-611
20. Jacquet, A., Coulon, L., De Neve, J., Daminet, V., Haumont, M., Garcia, L., Bollen, A., Jurado, M., and Biemans, R. (2001) Mol. Biochem. Parasitol. 116, 35-44
21. Di Costanzo, L., Gomez, G. A., and Christianson, D. W. (2007) J. Mol. Biol. 366, 481-493
22. Grujic, O., Grigg, M. E., and Boulanger, M. J. (2008) Acta crystallogr. 64, 425-427
23. Pflugrath, J. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 1718-1725
24. Collaborative Computational Project, Number 4 (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763
25. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. 53, 240-255
26. Schwarzenbacher, R., Godzik, A., Grzechnik, S. K., and Jaroszewski, L. (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. 60, 1229-1236
27. Perrakis, A., Morris, R., and Lamzin, V. S. (1999) Nat. Struct. Biol. 6, 458-463
28. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. 60, 2126-2132
29. Koch, M., and Bordas, J. (1983) J. Nucl. Instrum. Methods 208, 461-469
30. Guinier, A., and Fournet, F. (1955) Small Angle Scattering of X-rays, Wiley Interscience, New York, NY
31. Svergun, D. I. (1992) J. Appl. Crystallogr. 25, 495-503
32. Bergmann, A., Fritz, G., and Glatter, O. (2000) J. Appl. Crystallogr. 33, 1212-1216
33. Svergun, D. I., Petoukhov, M. V., and Koch, M. H. (2001) Biophys. J. 80, 2946-2953
34. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680
35. Saitou, N., and Nei, M. (1987) Mol. Biol. Evol. 4, 406-425
36. Holm, L., and Sander, C. (1996) Science 273, 595-603
37. Channon, J. Y., Seguin, R. M., and Kasper, L. H. (2000) Infect. Immun. 68, 4822-4826
38. Caiolfa, V. R., Zamai, M., Malengo, G., Andolfo, A., Madesn, C. D., Sutin, J., Digman, M. A., Gratton, E., Blasi, F., and Sidenius, N. (2007) J. Cell Biol. 179, 1067-1082
39. Westmeyer, G. G., Willem, M., Lichtenthaler, S. F., Lurman, G., Multhaup, G., Assfalg-Machleidt, I., Reiss, K., Saftig, P., and Haass, C. (2004) J. Biol. Chem. 279, 53205-53212
40. Konarev, P. V., Volkov, V. V., Sokolova, A. V., Koch, M. H., and Svergun, D. I. (2003) J. Appl. Crystallogr. 36, 1277-1282
41. Putnam, C. D., Hammel, M., Hura, G. L., and Tainer, J. A. (2007) Q. Rev. Biophys. 40, 191-285
42. Petoukhov, M. V., Eady, N. A., Brown, K. A., and Svergun, D. I. (2002) Biophys. J. 83, 3113-3125
43. Delano, W. L. (2002) The PyMOL Molecular Graphics System, Delano Scientific, San Carlos, CA
44. Bond, C. S. (2003) Bioinformatics 19, 311-312