C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery

BMC Medical Genetics

Volumn 10, Issue , 2009, Pages

  Perry, Tjörvi E ^a   Muehlschlegel, Jochen D ^a   Liu, Kuang Yu ^a   Fox, Amanda A ^a   Collard, Charles D ^b   Body, Simon C ^a   Shernan, Stanton K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b ST LUKE S EPISCOPAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN;

AGED; ALLELE; ARTICLE; BLOOD TRANSFUSION; BODY MASS; CARDIOPULMONARY BYPASS; CORONARY ARTERY BYPASS GRAFT; ELECTIVE SURGERY; FEMALE; GENE IDENTIFICATION; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PROTEIN BLOOD LEVEL; PROTEIN VARIANT; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SURGICAL RISK; ACUTE PHASE RESPONSE; COHORT ANALYSIS; GENETICS; GENOTYPE; MIDDLE AGED; RISK FACTOR; STATISTICAL MODEL;

ACUTE-PHASE REACTION; AGED; C-REACTIVE PROTEIN; CARDIOPULMONARY BYPASS; COHORT STUDIES; CORONARY ARTERY BYPASS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; POSTOPERATIVE PERIOD; RISK FACTORS;

EID: 66149102462     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-10-38     Document Type: Article

References (45)

1. Armani A Becker RC The biology, utilization, and attenuation of C-reactive protein in cardiovascular disease: Part I Am Heart J 2005, 149(6):971-976. 15976777 10.1016/j.ahj.2004.12.031
2. Pepys MB Hirschfield GM C-reactive protein: A critical update J Clin Invest 2003, 111(12):1805-1812. 161431 12813013
3. Agrawal A CRP after 2004 Mol Immunol 2005, 42(8):927-930. 15829284 10.1016/j.molimm.2004.09.028
4. Kaplan MH Volanakis JE Interaction of C-reactive protein complexes with the complement system. I. Consumption of human complement associated with the reaction of C-reactive protein with pneumococcal C-polysaccharide and with the choline phosphatides, lecithin and sphingomyelin J Immunol 1974, 112(6):2135-2147. 4151108
5. Mold C Gewurz H Du Clos TW Regulation of complement activation by C-reactive protein Immunopharmacology 1999, 42(1-3):23-30. 10408362 10.1016/S0162-3109(99)00007-7
6. Pasceri V Willerson JT Yeh ET Direct proinflammatory effect of C-reactive protein on human endothelial cells Circulation 2000, 102(18):2165-2168. 11056086
7. Agrawal A Cha-Molstad H Samols D Kushner I Transactivation of C-reactive protein by IL-6 requires synergistic interaction of CCAAT/enhancer binding protein beta (C/EBP beta) and Rel p50 J Immunol 2001, 166(4):2378-2384. 11160296
8. Koenig W Sund M Frohlich M Fischer HG Lowel H Doring A Hutchinson WL Pepys MB C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992 Circulation 1999, 99(2):237-242. 9892589
9. Mendall MA Strachan DP Butland BK Ballam L Morris J Sweetnam PM Elwood PC C-reactive protein: Relation to total mortality, cardiovascular mortality and cardiovascular risk factors in men Eur Heart J 2000, 21(19):1584-1590. 10988010 10.1053/euhj.1999.1982
10. Ridker PM Hennekens CH Buring JE Rifai N C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women N Engl J Med 2000, 342(12):836-843. 10733371 10.1056/ NEJM200003233421202
11. Ridker PM Buring JE Shih J Matias M Hennekens CH Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women Circulation 1998, 98(8):731-733. 9727541
12. Lindahl B Toss H Siegbahn A Venge P Wallentin L Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. FRISC Study Group. Fragmin during Instability in Coronary Artery Disease N Engl J Med 2000, 343(16):1139-1147. 11036119 10.1056/NEJM200010193431602
13. Mendall MA Patel P Ballam L Strachan D Northfield TC C reactive protein and its relation to cardiovascular risk factors: A population based cross sectional study Bmj 1996, 312(7038):1061-1065. 2350910 8616412
14. MacGregor AJ Gallimore JR Spector TD Pepys MB Genetic effects on baseline values of C-reactive protein and serum amyloid a protein: A comparison of monozygotic and dizygotic twins Clin Chem 2004, 50(1):130-134. 14633907 10.1373/clinchem.2003.028258
15. Retterstol L Eikvar L Berg K A twin study of C-Reactive Protein compared to other risk factors for coronary heart disease Atherosclerosis 2003, 169(2):279-282. 12921979 10.1016/S0021-9150(03)00192-8
16. Suk HJ Ridker PM Cook NR Zee RY Relation of polymorphism within the C-reactive protein gene and plasma CRP levels Atherosclerosis 2005, 178(1):139-145. 15585211 10.1016/j.atherosclerosis.2004.07.033
17. Chen J Zhao J Huang J Su S Qiang B Gu D -717A>G polymorphism of human C-reactive protein gene associated with coronary heart disease in ethnic Han Chinese: The Beijing atherosclerosis study J Mol Med 2005, 83(1):72-78. 15517131 10.1007/s00109-004-0585-5
18. Crawford DC Sanders CL Qin X Smith JD Shephard C Wong M Witrak L Rieder MJ Nickerson DA Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey Circulation 2006, 114(23):2458-2465. 17101857 10.1161/ CIRCULATIONAHA.106.615740
19. Miller DT Zee RY Suk Danik J Kozlowski P Chasman DI Lazarus R Cook NR Ridker PM Kwiatkowski DJ Association of common CRP gene variants with CRP levels and cardiovascular events Ann Hum Genet 2005, 69(Pt 6):623-638. 16266402 10.1111/j.1529-8817.2005.00210.x
20. Reiner AP Barber MJ Guan Y Ridker PM Lange LA Chasman DI Walston JD Cooper GM Jenny NS Rieder MJ Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein Am J Hum Genet 2008, 82(5):1193-1201. 18439552 10.1016/ j.ajhg.2008.03.017 2427318
21. Ridker PM Pare G Parker A Zee RY Danik JS Buring JE Kwiatkowski D Cook NR Miletich: JP Chasman DI Loci related to metabolic-syndrome pathways including LEPR, HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: The Women's Genome Health Study Am J Hum Genet 2008, 82(5):1185-1192. 18439548 10.1016/j.ajhg.2008.03.015 2427311
22. Collard CD Shernan SK Fox AA Bernig T Chanock SJ Vaughn WK Takahashi K Ezekowitz AB Jarolim P Body SC The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery Circulation 2007, 116(11 Suppl):I106-112. 17846289
23. Hage FG Szalai AJ C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk J Am Coll Cardiol 2007, 50(12):1115-1122. 17868801 10.1016/j.jacc.2007.06.012
24. de Bakker PI Yelensky R Pe'er I Gabriel SB Daly MJ Altshuler D Efficiency and power in genetic association studies Nat Genet 2005, 37(11):1217-1223. 16244653 10.1038/ng1669
25. Stephens M Scheet P Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation Am J Hum Genet 2005, 76(3):449-462. 15700229 10.1086/428594 1196397
26. Stephens M Smith NJ Donnelly P A new statistical method for haplotype reconstruction from population data Am J Hum Genet 2001, 68(4):978-989. 11254454 10.1086/319501 1275651
27. Imai K King G Lau O Toward A Common Framework for Statistical Analysis and Development Journal of Computational and Graphical Statistics 2008, 17(4):892-913. 10.1198/106186008X384898
28. Canty A Ripley B Boot: Bootstrap R (S-Plus) Functions Version 1.2-36 2009.
29. Davison AC Hinkley DV Bootstrap Methods and their Application New York, NY: Cambridge University Press 1997.
30. R Development Core Team R: A Language and Environment for Statistical Computing Vienna, Austria: R Foundation for Statistical Computing 2008.
31. Purcell S Neale B Todd-Brown K Thomas L Ferreira MA Bender D Maller J Sklar P de Bakker PI Daly MJ et al. PLINK: A tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 2007, 81(3):559-575. 17701901 10.1086/519795 1950838
32. Carlson CS Aldred SF Lee PK Tracy RP Schwartz SM Rieder M Liu K Williams OD Iribarren C Lewis EC et al. Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels Am J Hum Genet 2005, 77(1):64-77. 15897982 10.1086/431366 1226195
33. Davey Smith G Lawlor DA Harbord R Timpson N Rumley A Lowe GD Day IN Ebrahim S Association of C-reactive protein with blood pressure and hypertension: Life course confounding and mendelian randomization tests of causality Arterioscler Thromb Vasc Biol 2005, 25(5):1051-1056. 15731495 10.1161/01.ATV.0000160351.95181.d0
34. Eklund C Kivimaki M Islam MS Juonala M Kahonen M Marniemi J Lehtimaki T Viikari J Raitakari OT Hurme M C-reactive protein genetics is associated with carotid artery compliance in men in The Cardiovascular Risk in Young Finns Study Atherosclerosis 2008, 196(2):841-848. 17350021 10.1016/ j.atherosclerosis.2007.01.027
35. Russell AI Cunninghame Graham DS Shepherd C Roberton CA Whittaker J Meeks J Powell RJ Isenberg DA Walport MJ Vyse TJ Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus Hum Mol Genet 2004, 13(1):137-147. 14645206 10.1093/hmg/ddh021
36. Kolz M Koenig W Muller M Andreani M Greven S Illig T Khuseyinova N Panagiotakos D Pershagen G Salomaa V et al. DNA variants, plasma levels and variability of C-reactive protein in myocardial infarction survivors: Results from the AIRGENE study Eur Heart J 2008, 29(10):1250-1258. 17956875 10.1093/eurheartj/ehm442
37. Lange LA Carlson CS Hindorff LA Lange EM Walston J Durda JP Cushman M Bis JC Zeng D Lin D et al. Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events JAMA 2006, 296(22):2703-2711. 17164456 10.1001/jama.296.22.2703
38. Brull DJ Serrano N Zito F Jones L Montgomery HE Rumley A Sharma P Lowe GD World MJ Humphries SE et al. Human CRP gene polymorphism influences CRP levels: Implications for the prediction and pathogenesis of coronary heart disease Arterioscler Thromb Vasc Biol 2003, 23(11):2063-2069. 12842840 10.1161/01.ATV.0000084640.21712.9C
39. Shen LX Basilion JP Stanton VP Jr Single-nucleotide polymorphisms can cause different structural folds of mRNA Proc Natl Acad Sci USA 1999, 96(14):7871-7876. 10393914 10.1073/pnas.96.14.7871 22154
40. Kimchi-Sarfaty C Oh JM Kim IW Sauna ZE Calcagno AM Ambudkar SV Gottesman MM A "silent" polymorphism in the MDR1 gene changes substrate specificity Science 2007, 315(5811):525-528. 17185560 10.1126/ science.1135308
41. Kathiresan S Larson MG Vasan RS Guo CY Gona P Keaney JF Jr Wilson PW Newton-Cheh C Musone SL Camargo AL et al. Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level Circulation 2006, 113(11):1415-1423. 16534007 10.1161/ CIRCULATIONAHA.105.591271
42. Kovacs A Green F Hansson LO Lundman P Samnegard A Boquist S Ericsson CG Watkins H Hamsten A Tornvall P A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein Atherosclerosis 2005, 178(1):193-198. 15585218 10.1016/ j.atherosclerosis.2004.08.018
43. Suk Danik J Chasman DI Cannon CP Miller DT Zee RY Kozlowski P Kwiatkowski DJ Ridker PM Influence of genetic variation in the C-reactive protein gene on the inflammatory response during and after acute coronary ischemia Ann Hum Genet 2006, 70(Pt 6):705-716. 17044845 10.1111/j.1469-1809.2006.00272.x
44. Wang Q Hunt SC Xu Q Chen YE Province MA Eckfeldt JH Pankow JS Song Q Association study of CRP gene polymorphisms with serum CRP level and cardiovascular risk in the NHLBI Family Heart Study Am J Physiol Heart Circ Physiol 2006, 291(6):H2752-2757. 16731635 10.1152/ ajpheart.01164.2005
45. Szalai AJ Wu J Lange EM McCrory MA Langefeld CD Williams A Zakharkin SO George V Allison DB Cooper GS et al. Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level J Mol Med 2005, 83(6):440-447. 15778807 10.1007/s00109-005-0658-0