O-demethylation of dextromethorphan using microbial cultures

Drug Metabolism Letters

Volumn 3, Issue 1, 2009, Pages 10-14

  Prasanthi, Samathoti ^a   Vidyavathi, Maravajhala ^a   Prasad, Koganti V S R G ^a   Krishna, Devarakonda Rama ^b  

^a INSTITUTE OF PHARMACEUTICAL TECHNOLOGY   (India)

^b MEDTRONIC INC   (United States)

Author keywords

CYP 2D6; Dextromethorphan; Dextrorphan; Microbial transformation; Oxidative demethylation; Saccharomyces cerevisiae

Indexed keywords

CYTOCHROME P450 2D6; DEXTROMETHORPHAN; DEXTRORPHAN; DRUG METABOLITE;

ARTICLE; ASPERGILLUS NIGER; ASPERGILLUS TERREUS; BACTERIUM CULTURE; CONTROLLED STUDY; CUNNINGHAMELLA ELEGANS; DEMETHYLATION; DRUG METABOLISM; DRUG TRANSFORMATION; FUNGAL STRAIN; FUNGUS CULTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROORGANISM; NOCARDIA; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SACCHAROMYCES CEREVISIAE; SCREENING; STREPTOMYCES GRISEUS;

ANTITUSSIVE AGENTS; BACTERIA; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP2D6; DEALKYLATION; DEXTROMETHORPHAN; DEXTRORPHAN; FUNGI; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; SACCHAROMYCES CEREVISIAE; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 66149095124     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231209787176326     Document Type: Article

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