Cytogenetic abnormalities in multiple myeloma: poor prognosis linked to concomitant detection in random and focal lesion bone marrow samples and associated with high-risk gene expression profile

British Journal of Haematology

Volumn 145, Issue 5, 2009, Pages 637-641

  Zhou, Yiming ^a   Nair, Bijay ^a   Shaughnessy Jr , John D ^a   Cartron, Marie Astrid ^a   Haessler, Jeff ^b   Anaissie, Elias ^a   Van Rhee, Frits ^a   Crowley, John ^b   Barlogie, Bart ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b USA   (United States)

Author keywords

Cytogenetics; Focal lesions; Gene array; Myeloma; Prognosis

Indexed keywords

PROTEIN P53;

ARTICLE; BONE MARROW BIOPSY; CONTROLLED STUDY; CYTOGENETICS; EVENT FREE SURVIVAL; GENE EXPRESSION PROFILING; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MULTIPLE MYELOMA; OVERALL SURVIVAL; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; RANDOM SAMPLE;

AGED; BONE MARROW; BONE MARROW EXAMINATION; CHROMOSOME ABERRATIONS; DISEASE-FREE SURVIVAL; GENE EXPRESSION PROFILING; HUMANS; MIDDLE AGED; MULTIPLE MYELOMA; MULTIVARIATE ANALYSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SURVIVAL RATE;

EID: 66149087321     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07670.x     Document Type: Article

References (14)

1. Barlogie, B., Jagannath, S., Vesole, D.H., Naucke, S., Cheson, B., Mattox, S., Bracy, D., Salmon, S., Jacobson, J., Crowley, J. Tricot, G. (1997) Superiority of tandem autologous transplantation over standard therapy for previously untreated multiple myeloma. Blood, 89, 789 793. (Pubitemid 27121271)
2. Barlogie, B., Tricot, G., Anaissie, E., Shaughnessy, J., Rasmussen, E., van Rhee, F., Fassas, A., Zangari, M., Hollmig, K., Pineda-Roman, M., Lee, C., Talamo, G., Thertulien, R., Kiwan, E., Krishna, S., Fox, M. Crowley, J. (2006) Thalidomide and hematopoietic-cell transplantation for multiple myeloma. New England Journal of Medicine, 354, 1021 1030. (Pubitemid 43357806)
3. Barlogie, B., Anaissie, E., van Rhee, F., Haessler, J., Hollmig, K., Pineda-Roman, M., Cottler-Fox, M., Mohiuddin, A., Alsayed, Y., Tricot, G., Bolejack, V., Zangari, M., Epstein, J., Petty, N., Steward, D., Jenkins, B., Gurley, J., Sullivan, E., Crowley, J. Shaughnessy, Jr., J.D. (2007) Incorporating bortezomib into upfront treatment for multiple myeloma: early results of total therapy 3. British Journal of Haematology, 138, 176 185. (Pubitemid 46978271)
4. Cox, D.R. (1972) Regression models and life-tables. Journal of the Royal Statistical Society B, 34, 187 220.
5. Durie, B.G. Salmon, S.E. (1975) A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer, 36, 842 854.
6. Durie, B.G., Harousseau, J.L., Miguel, J.S., Blade, J., Barlogie, B., Anderson, K., Gertz, M., Dimopoulos, M., Westin, J., Sonneveld, P., Ludwig, H., Gahrton, G., Beksac, M., Crowley, J., Belch, A., Boccadaro, M., Cavo, M., Turesson, I., Joshua, D., Vesole, D., Kyle, R., Alexanian, R., Tricot, G., Attal, M., Merlini, G., Powles, R., Richardson, P., Shimizu, K., Tosi, P., Morgan, G. Rajkumar, S.V. (2006) International uniform response criteria for multiple myeloma. Leukemia, 20, 1467 1473. (Pubitemid 44264086)
7. Kaplan, E.L. Meier, P. (1958) Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53, 457 481.
8. Kyle, R.A., Remstein, E.D., Therneau, T.M., Dispenzieri, A., Kurtin, P.J., Hodnefield, J.M., Larson, D.R., Plevak, M.F., Jelinek, D.F., Fonseca, R., Melton, III., R. Rajkumar, S.V. (2007) Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma. New England Journal of Medicine, 356, 2582 2590. (Pubitemid 46961003)
9. Shaughnessy, Jr., J.D., Zhan, F., Burington, B.E., Huang, Y., Colla, S., Hanamura, I., Stewart, J.P., Kordsmeier, B., Randolph, C., Williams, D.R., Xiao, Y., Xu, H., Epstein, J., Anaissie, E., Krishna, S.G., Cottler-Fox, M., Hollmig, K., Mohiuddin, A., Pineda-Roman, M., Tricot, G., van Rhee, F., Sawyer, J., Alsayed, Y., Walker, R., Zangari, M., Crowley, J. Barlogie, B. (2007) A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1. Blood, 109, 2276 2284. (Pubitemid 46425864)
10. Tian, E., Zhan, F., Walker, R., Rasmussen, E., Ma, Y., Barlogie, B. Shaughnessy, Jr., J.D. (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. New England Journal of Medicine, 349, 2483 2494. (Pubitemid 38010074)
11. Walker, R., Barlogie, B., Haessler, J., Tricot, G., Anaissie, E., Shaughnessy, Jr., J.D., Epstein, J., van Hemert, R., Erdem, E., Hoering, A., Crowley, J., Ferris, E., Hollmig, K., van Rhee, F., Zangari, M., Pineda-Roman, M., Mohiuddin, A., Yaccoby, S., Sawyer, J. Angtuaco, E.J. (2007) Magnetic resonance imaging in multiple myeloma: diagnostic and clinical implications. Journal of Clinical Oncology, 25, 1121 1128. (Pubitemid 46596765)
12. Xiong, W., Shaughnessy, JrJD., Starnes, S., Johnson, S., Huang, Y., Barlogie, B. Zhan, F. (2008) An anaylsis of the clinical and biological significance of TP53 loss in multiple myeloma. Blood, 112, 4235 4246.
13. Yaccoby, S., Pearse, R.N., Johnson, C.L., Barlogie, B., Choi, Y. Epstein, J. (2002) Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. British Journal of Haematology, 116, 278 290. (Pubitemid 34156975)
14. Zhan, F., Huang, Y., Colla, S., Stewart, J.P., Hanamura, I., Gupta, S., Epstein, J., Yaccoby, S., Sawyer, J., Burington, B., Anaissie, E., Hollmig, K., Pineda-Roman, M., Tricot, G., van Rhee, F., Walker, R., Zangari, M., Crowley, J., Barlogie, B. Shaughnessy, Jr., J.D. (2006) The molecular classification of multiple myeloma. Blood, 108, 2020 2028. (Pubitemid 44395016)