Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells

Thorax

Volumn 64, Issue 5, 2009, Pages 430-435

  Ward, C ^a,b   Eger, K ^a   Diboll, J ^a   Jones, D ^a   Haniffa, M A ^a   Brodlie, M ^a   Fisher, A ^a   Lordan, J L ^a   Corris, P A ^a   Hilkens, C M U ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b FREEMAN HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD68 ANTIGEN; FLUORESCEIN ISOTHIOCYANATE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MANNOSE RECEPTOR; T6 ANTIGEN;

ADULT; ALLOIMMUNITY; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CLINICAL ARTICLE; CYTOKINE RELEASE; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG TRANSPLANTATION; MACROPHAGE; MIXED LYMPHOCYTE REACTION; MONOCYTE; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; RECIPIENT; RESPIRATORY EPITHELIUM; T LYMPHOCYTE;

EID: 66049130810     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2008.104067     Document Type: Article

References (23)

1. Corris PA, Christie JD. Update in transplantation 2007. Am J Respir Crit Care Med 2008;177:1062-1067
2. Holt PG. Pulmonary dendritic cells in local immunity to inert and pathogenic antigens in the respiratory tract. Proc Am Thorac Soc 2005;2:116-120 (Pubitemid 41233377)
3. Yousem SA, Ray L, Paradis IL, et al. Potential role of dendritic cells in bronchiolitis obliterans in heart-lung transplantation. Ann Thorac Surg 1990;49:424-428
4. Leonard CT, Soccal PM, Singer L, et al. Dendritic cells and macrophages in lung allografts: a role in chronic rejection? Am J Respir Crit Care Med 2000;161:1349-1354
5. Milne DS, Gascoigne AD, Coaker J, et al. Mononuclear phagocyte populations in the transplanted human lung. Transplantation 1998;66:671-673
6. Murphy DM, Forrest IA, Corris PA, et al. Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients. Am J Physiol Lung Cell Mol Physiol 2008;294:L592-9.
7. Jahnsen FL, Strickland DH, Thomas JA, et al. Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus. J Immunol 2006;177:5861-5867
8. Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008;8:193-204.
9. Regamey N, Obregon C, Ferrari-Lacraz S, et al. Airway epithelial IL15 transforms monocytes into dendritic cells. Am J Respir Cell Mol Biol 2007;37:75-84.
10. Estenne M, Hertz MI. Bronchiolitis obliterans after human lung transplantation. Am J Respir Crit Care Med 2002;166:440-444
11. British Thoracic Society. British Thoracic Society guidelines on diagnostic flexible bronchoscopy. Thorax 2001;56(Suppl 1):i1-21.
12. Stewart S, Fishbein MC, Snell GI, et al. Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant 2007;26:1229-1242
13. Forrest IA, Murphy DM, Ward C, et al. Primary airway epithelial cell culture from lung transplant recipients. Eur Respir J 2005;26:1080-1085
14. Anderson AE, Sayers BL, Haniffa MA, et al. Differential regulation of naive and memory CD4+ T cells by alternatively activated dendritic cells. J Leukoc Biol 2008;84:124-133
15. Chomarat P, Dantin C, Bennett L, et al. TNF skews monocyte differentiation from macrophages to dendritic cells. J Immunol 2003;171:2262-2269
16. Nicod LP. Mechanisms of airway obliteration after lung transplantation. Proc Am Thorac Soc 2006;3:444-449 (Pubitemid 44033361)
17. Ohtoshi T, Vancheri C, Cox G, et al. Monocyte-macrophage differentiation induced by human upper airway epithelial cells. Am J Respir Cell Mol Biol 1991;4:255-263
18. Mayer AK, Bartz H, Fey F, et al. Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment. Eur J Immunol 2008;38:1689-1699
19. Marriott HM, Dockrell DH. The role of the macrophage in lung disease mediated by bacteria. Exp Lung Res 2007;33:493-505. (Pubitemid 350256094)
20. Anderson RL, Hiemstra PS, Ward C, et al. Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome. Eur Respir J 2008;32:670-677
21. Davidson DJ, Currie AJ, Reid GS, et al. The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization. J Immunol 2004;172:1146-1156
22. Fujita S, Seino K, Sato K, et al. Regulatory dendritic cells act as regulators of acute lethal systemic inflammatory response. Blood 2006;107:3656-3664
23. Li Q, Guo Z, Xu X, et al. Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. Eur J Immunol 2008;38:2751-2761