BF3·Et2O catalyzed diastereoselective nucleophilic reactions of 3-silyloxypiperidine N,O-acetal with silyl enol ether and application to the asymmetric synthesis of (+)-febrifugine

Tetrahedron Letters

Volumn 50, Issue 28, 2009, Pages 4046-4049

  Liu, Ru Cheng ^a   Huang, Wei ^a   Ma, Jing Yi ^a   Wei, Bang Guo ^a   Lin, Guo Qiang ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Alkaloid; Asymmetric synthesis; N,O Acetal; Nucleophilic substitution; Piperidine

Indexed keywords

3 SILYLOXYPIPERIDINE; ACETAL; ETHER DERIVATIVE; FEBRIFUGINE; NUCLEOPHILE; PIPERIDINE DERIVATIVE; SILYL ETHER; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 66049093028     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.04.097     Document Type: Article

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