Familial idiopathic pulmonary fibrosis in association with bone marrow hypoplasia and hepatic nodular regenerative hyperplasia: A new "trimorphic" syndrome

Thorax

Volumn 64, Issue 5, 2009, Pages 440-443

  Talbot Smith, A ^a   Syn, W K ^b   MacQuillan, G ^c   Neil, D ^b   Elias, E ^b   Ryan, P ^a  

^a HEREFORD COUNTY HOSPITAL   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^c SIR CHARLES GAIRDNER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; PREDNISOLONE;

ADULT; AGED; ARTICLE; BONE MARROW BIOPSY; BONE MARROW HYPOPLASIA; CASE REPORT; CLINICAL FEATURE; DETERIORATION; DISEASE ASSOCIATION; FIBROSING ALVEOLITIS; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LIVER BIOPSY; LIVER FUNCTION TEST; LIVER HISTOLOGY; LIVER HYPERPLASIA; LUNG FUNCTION TEST; MALE; PLEURA THICKENING; PORTAL HYPERTENSION; PRIORITY JOURNAL; SYNDROME; TREATMENT RESPONSE;

EID: 66049090410     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2008.099796     Document Type: Article

References (21)

1. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. Am J Respir Crit Care Med 2000;161:646-664
2. Marshall RP, Puddicombe A, Cookson WOC, et al. Adult familial cryptogenic fibrosing alveolitis in the United Kingdom. Thorax 2000;55:143-146
3. Bitterman PBSI, Rennard BA, Keogh MD, et al. Familial idiopathic pulmonary fibrosis. Evidence of lung inflammation in unaffected family members. N Engl J Med 1986;314:1343-1347
4. Lee HA, Ryu JH, Wittner MH, et al. Familal idiopathic pulmonary fibrosis. Clinical features and outcome. Chest 2005;127:2034-2041
5. Steele MP, Speer M, Loyd JE, et al. Clinical and pathological features of familial interstitial pneumonia. Am J Respir Crit Care Med 2005;172:1146-1152
6. Hubbard R, Lewis S, Richards K, et al. Occupational exposure to metal or wood dust and aetiology of cryptogenic fibrosing alveolitis. Lancet 1996;347:284-289
7. Selman M, Pardo A. The epithelial/fibroblastic pathway in the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 2003;29(Suppl 3):S93-7. (Pubitemid 37070317)
8. Grutters J, du Bois R. Genetics of fibrosing lung diseases. Eur Respir J 2005;25:915-927
9. Phillips R, Burdick M, Hong K, et al. Circulating fibrocytes traffic to the lungs in response to CXCL 12 and mediate fibrosis. J Clin Invest 2004;114:438-446
10. Mehrad B, Burdick M, Zisman D, et al. Circulating peripheral blood lymphocytes in human fibrotic interstitial lung disease. Biochem Biophys Res Commun 2007;353:104-108
11. Wanless I. Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 1990;11:787-797 (Pubitemid 20191384)
12. Gonzalez-Huezo MS, Villela LM, Zepeda-Florencio Mdel C, et al. Nodular regenerative hyperplasia associated to aplastic anaemia: a case report and literature review. Ann Hepatol 2006;5:166-169
13. Wanless IR, Godwin TA, Allen F, et al. Nodular regenerative hyperplasia of the liver in hematologic disorders: a possible response to obliterative portal venopathy. A morphometric study of nine cases with an hypothesis on the pathogenesis. Medicine 1980;59:367-379
14. Wanless IR, Mawdsley C, Adams R. On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology 1985;5:1194-1200 (Pubitemid 16222291)
15. Shimamatsu K, Wanless IR. Role of ischemia in causing apoptosis, atrophy, and nodular hyperplasia in human liver. Hepatology 1997;26:343-350 (Pubitemid 27328311)
16. Wanless IR, Solt LC, Kortan P, et al. Nodular regenerative hyperplasia of the liver associated with maroglobulinaemia. A clue to the pathogenesis. Am J Med 1981;70:1203-1209
17. Austin A, Campbell E, Lane P, et al. Nodular regenerative hyperplasia of the liver and coeliac disease: potential role of IgA anticardiolipin antibody. Gut 2004;53:1032-1034
18. Chambers R. Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention. Br J Pharmacol 2008;153(Suppl 1):S367-78.
19. Young N, Mortimer P. Viruses and bone marrow failure. Blood 1984;63:729-737 (Pubitemid 14141290)
20. Rosenthal R, Blackman A. Bone marrow hypoplasia following use of chloramphenicol eye drops. JAMA 1965;191:136-137
21. Feng C, Ng M, Szeto R, et al. Bone marrow findings in lupus patients with pancytopenia. Pathology 199;23:5-7.