Complex interactions in the regulation of trypanosome mitochondrial gene expression

Trends in Parasitology

Volumn 25, Issue 6, 2009, Pages 252-255

  Koslowsky, Donna J ^a  

^a Michigan State University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUIDE RNA; MESSENGER RNA;

ADAPTATION; COMPLEX FORMATION; ENERGY METABOLISM; ENVIRONMENTAL FACTOR; GENE EXPRESSION; HOST; HOST PARASITE INTERACTION; MITOCHONDRIAL GENE; MITOCHONDRIAL GENOME; MITOCHONDRION; NONHUMAN; POLYADENYLATION; PROTEIN ANALYSIS; REGULATORY MECHANISM; SHORT SURVEY; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

ANIMALS; DNA, KINETOPLAST; GENE EXPRESSION REGULATION; GENES, MITOCHONDRIAL; MITOCHONDRIA; PROTOZOAN PROTEINS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 66049088247     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2009.03.008     Document Type: Short Survey

References (24)

1. Van Hellemond J.J., et al. The extraordinary mitochondrion and unusual citric acid cycle in Trypanosoma brucei. Biochem. Soc. Trans. 33 (2005) 967-971
2. Bringaud F., et al. Energy metabolism of trypanosomatids: adaptation to available carbon sources. Mol. Biochem. Parasitol. 149 (2006) 1-9
3. Lukes J., et al. Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastids flagellates. Curr. Genet. 48 (2005) 277-299
4. Stuart K.D., et al. Complex management: RNA editing in trypanosomes. Trends Biochem. Sci. 30 (2005) 97-105
5. Carnes J., et al. RNA Editing in Trypanosoma brucei requires three different editosomes. Mol. Cell. Biol. 28 (2008) 122-130
6. Etheridge R.D., et al. 3′ adenylation determines mRNA abundance and monitors completion of RNA editing in T. brucei mitochondria. EMBO J. 27 (2008) 1596-1608
7. Weng J., et al. Guide RNA-binding complex from mitochondria of trypanosomatids. Mol. Cell 32 (2008) 198-209
8. Adler B.K., et al. Modification of Trypanosoma brucei mitochondrial rRNA by posttranscriptional 3′ polyuridine tail formation. Mol. Cell. Biol. 11 (1991) 5878-5884
9. Bhat G.J., et al. Transcript-specific developmental regulation of polyadenylation in Trypanosoma brucei mitochondria. Mol. Biochem. Parasitol. 52 (1992) 231-240
10. Feagin J.E., and Stuart K. Developmental aspects of uridine addition within mitochondrial transcripts of Trypanosoma brucei. Mol. Cell. Biol. 8 (1988) 1259-1265
11. Panigrahi A.K., et al. Mitochondrial complexes in Trypanosoma brucei. Mol. Cell. Proteomics 7 (2008) 534-545
12. Hashimi H., et al. TbRGG1, an essential protein involved in kinetoplastids RNA metabolism that is associated with a novel multiprotein complex. RNA 14 (2008) 970-980
13. Aphasizhev R., et al. A 100-kD complex of two RNA-binding proteins from mitochondria of Leishmania tarentolae catalyzes RNA annealing and interacts with several RNA editing components. RNA 9 (2003) 62-76
14. Lurin C., et al. Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis. Plant Cell 16 (2004) 2089-2103
15. Delannoy E., et al. Pentatricopeptide repeat (PPR) proteins as sequence-specificity factors in post-transcriptional processes in organelles. Biochem. Soc. Trans. 35 (2007) 1643-1647
16. Mingler M.K., et al. Identification of pentatricopeptide repeat proteins in Trypanosoma brucei. Mol. Biochem. Parasitol. 150 (2006) 37-45
17. Pusnik M., et al. Pentatricopeptide repeat proteins in Trypanosoma brucei function in mitochondrial ribosomes. Mol. Cell. Biol. 27 (2007) 6876-6888
18. Zikova A., et al. Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei. Int. J. Parasitol. 38 (2008) 901-912
19. Koslowsky D.J., et al. Mitochondrial mRNA 3′ cleavage/polyadenylation and RNA editing in Trypanosoma brucei are independent events. Mol. Biochem. Parasitol. 90 (1997) 81-94
20. Simpson L. The genomic organization of guide RNA genes in kinetoplastids protozoa: several conundrums and their solutions. Mol. Biochem. Parasitol. 86 (1997) 133-141
21. Grams J., et al. Processing of polycistronic guide RNA transcripts is associated with RNA editing complexes in Trypanosoma brucei. EMBO J. 19 (2000) 5525-5532
22. Koslowsky D.J., et al. Guide RNAs for transcripts with developmentally regulated RNA editing are present in both life cycle stages of Trypanosoma brucei. Mol. Cell. Biol. 12 (1992) 2043-2049
23. Ochsenreiter T., et al. Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity. PLoS One 3 (2008) e1566
24. Clement S.L., et al. An intragencic guide RNA location suggests a complex mechanism for mitochondrial gene expression in Trypanosoma brucei. Euk. Cell 3 (2004) 862-869