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Volumn 7, Issue 11, 2009, Pages 2259-2264

A general strategy for the preparation of C-terminal peptide α-ketoacids by solid phase peptide synthesis

Author keywords

[No Author keywords available]

Indexed keywords

C-TERMINAL PEPTIDES; KETOACIDS; SIDE CHAINS; SOLID PHASE PEPTIDE SYNTHESIS; SOLID PHASE SYNTHESIS;

EID: 65949106377     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b901198f     Document Type: Article
Times cited : (40)

References (33)
  • 29
    • 0000647341 scopus 로고
    • Loading of the linker and solid phase peptide synthesis follows the general procedures described in Novabiochem catalogue, 2008 -3783
    • K. B. Sloan S. A. M. Koch J. Org. Chem. 1983 48 3777 3783
    • (1983) J. Org. Chem. , vol.48 , pp. 3777
    • Sloan, K.B.1    Koch, S.A.M.2
  • 32
    • 3342981841 scopus 로고
    • Hydroxylamines were prepared according to Fukuyama's method: -1906
    • R. J. Kennedy A. M. Stock J. Org. Chem. 1960 25 1901 1906
    • (1960) J. Org. Chem. , vol.25 , pp. 1901
    • Kennedy, R.J.1    Stock, A.M.2
  • 33
    • 85026878359 scopus 로고    scopus 로고
    • Fmoc-His-Ser-Phe-Pro sulfur ylide 25 was prepared by loading dipeptide Fmoc-Phe-Pro-OH onto sulfonium resin 9 followed by Fmoc-deprotection and elongation. Stepwise coupling with Fmoc-Pro-OH also provided the desired tetrapeptide sulfur ylide with somewhat lower yield Peptide targets 26-30 are fragments chosen from either a Fuzeon or human prostate-specific antigen protein with the sole purpose of demonstrating disconnection at ligation site with different amino acid residues -212
    • H. Tokuyama T. Kuboyama T. Fukuyama Org. Synth. 2003 80 207 212
    • (2003) Org. Synth. , vol.80 , pp. 207
    • Tokuyama, H.1    Kuboyama, T.2    Fukuyama, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.