Synthesis and DNA polymerase α and β inhibitory activity of alkyl p-coumarates and related compounds

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 5, 2009, Pages 476-480

  Nishimura, Katsumi ^a   Takenaka, Yukiko ^a   Kishi, Manami ^a   Tanahashi, Takao ^a   Yoshida, Hiromi ^b   Okuda, Chiaki ^b   Mizushina, Yoshiyuki ^b  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Alkyl p coumarate ester; DNA polymerase; Inhibitory activity

Indexed keywords

1 (4 HYDROXYPHENYL)DOCOS 1 EN 3 ONE; ARTEMISIA ANNUA EXTRACT; CCTADECYL 4 HYDROXYPHENYLPROPIOLATE; COUMARIC ACID; DECYL 4 COUMARATE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DOCOSYL 4 COUMARATE; DOCOSYL 4 HYDROXYPHENYLPROPIOLATE; DODECYL 4 COUMARATE; HEXADECYL 4 COUMARATE; ICOSYL 4 COUMARATE; ICOSYL 4 HYDROXYBENZOATE; ICOSYL 4 HYDROXYPHENYLPROPIOLATE; N OCTADECYL 4 COUMARAMIDE; OCTADECYL 2 COUMARATE; OCTADECYL 3 COUMARATE; OCTADECYL 4 COUMARATE; OCTADECYL 4 DIHYDROCOUMARATE; OCTADECYL CAFFEATE; OCTADECYL CINNAMATE; OCTADECYL FERULATE; OCTADECYL ISOFERULATE; OCTADECYL O METHYL 4 COUMARATE; OCTADECYL SINAPATE; TETRACOSYL 4 COUMARATE; TETRACOSYL 4 HYDROXYPHENYLPROPIOLATE; TETRADECYL 4 COUMARATE; TETRADECYL 4 HYDROXYPHENYLPROPIOLATE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ESTERIFICATION; METHYLATION; REDUCTION;

ANIMALS; COUMARIC ACIDS; DNA POLYMERASE BETA; DNA POLYMERASE I; ENZYME INHIBITORS; ESTERS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE;

EID: 65949095849     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.476     Document Type: Article

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