Prevalence and outcome of fungal infection in patients with severe acute pancreatitis

Journal of Gastroenterology and Hepatology (Australia)

Volumn 24, Issue 5, 2009, Pages 743-747

  Kochhar, Rakesh ^a   Ahammed, S K Mahiuddin ^a   Chakrabarti, Arunaloke ^b   Ray, Pallab ^b   Sinha, Saroj K ^a   Dutta, Usha ^a   Wig, Jai Dev ^c   Singh, Kartar ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b Departments of Gastroenterology

^c Department of Microbiology ^*

Author keywords

Candida; Fungal; Pancreatitis; Severe pancreatitis

Indexed keywords

AMIKACIN; AMPHOTERICIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CILASTATIN PLUS IMIPENEM; FLUCONAZOLE; IMIPENEM; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ACUTE PANCREATITIS; ADULT; ANTIBIOTIC PROPHYLAXIS; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL INFECTION; BLOOD CULTURE; CANDIDA ALBICANS; CANDIDA TROPICALIS; CLINICAL ARTICLE; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; ESCHERICHIA COLI; FEMALE; HOSPITALIZATION; HUMAN; HUMAN TISSUE; HYPOTENSION; INCIDENCE; INFECTION RISK; LOGISTIC REGRESSION ANALYSIS; MALE; MORBIDITY; MORTALITY; MYCOSIS; PREVALENCE; PRIORITY JOURNAL; RESPIRATORY FAILURE; RISK FACTOR; RISK REDUCTION; SURVIVAL; TOTAL PARENTERAL NUTRITION; TREATMENT DURATION; URINE CULTURE;

ADULT; AMPHOTERICIN B; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; FEMALE; FLUCONAZOLE; HUMANS; HYPOTENSION; LENGTH OF STAY; LOGISTIC MODELS; MALE; MIDDLE AGED; MYCOSES; ODDS RATIO; PANCREATECTOMY; PANCREATITIS, ACUTE NECROTIZING; PARENTERAL NUTRITION, TOTAL; PREVALENCE; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RESPIRATORY INSUFFICIENCY; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 65949095234     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05712.x     Document Type: Article

References (25)

1. Beger HG, Bittner R, Block S, Buchler M. Bacterial contamination of pancreatic necrosis. A prospective clinical study. Gastroenterology 1986 91 : 433 8. (Pubitemid 16098373)
2. Buchler MW, Gloor B, Muller CA, Friess H, Seiler CA, Uhi W. Acute necrotizing pancreatitis: treatment strategy according to the status of infection. Ann. Surg. 2000 232 : 619 26.
3. Dellinger EP, Tellado JM, Soto NE et al. Early antibiotic treatment for severe acute necrotizing pancreatitis. A randomized double blind, placebo-controlled study. Ann. Surg. 2007 245 : 674 83. (Pubitemid 46684095)
4. Villatoto E, Bassi C, Larvin M. Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis. Cochrane Database of Systemic Reviews. 2006 4 : article no.: CD002941. DOI: 10.1002/14651858.CD002941.pub2.
5. Shaumugam N, Isenmann R, Barkin JS, Berger HG. Pancreatic fungal infection. Pancreas 2003 27 : 133 38. (Pubitemid 36950724)
6. Beger HG, Ran B, Isenmann R. Natural history of necrotizing pancreatitis. Pancreatology 2003 3 : 93 101. (Pubitemid 36577069)
7. Isenmann R, Schwarz M, Rau B, Trautmann M, Schober W, Beger HG. Characteristics of infection with Candida species in patients with necrotizing pancreatitis. World J. Surg. 2002 25 : 372 76. (Pubitemid 36920418)
8. Grewe M, Tsiotos GG, Luque-de-Leon E, Sarr HGL. Fungal infection in acute necrotizing pancreatitis. J. Am. Coll. Surg. 1999 188 : 408 14. (Pubitemid 29162699)
9. Aloia T, Solomkin J, Fink AS et al. Candida in pancreatic infection: a clinical experience. J. Am. Surg. 1994 60 : 793 96. (Pubitemid 24299092)
10. De Waele JJ, Vogelaers D, Blot S, Colardyn F. Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy. Clin. Infect. Dis. 2003 37 : 208 13. (Pubitemid 36930351)
11. Hoerauf A, Hammer S, Muller-Myhsok B, Rupprecht H. Intraabdominal Candida infection during acute necrotizing pancreatitis has a high prevalence and is associated with increased mortality. Crit. Care Med. 1998 26 : 2010 15. (Pubitemid 29016683)
12. Gloor B, Muller CA, Worni M et al. Pancreatic infection in severe pancreatitis. The role of fungus and multiresistant organisms. Arch. Surg. 2001 136 : 592 96. (Pubitemid 32417551)
13. Connor S, Alexakis N, Neal T et al. Fungal infection but not type of bacterial infection is associated with a high mortality in primary and secondary infected pancreatic necrosis. Dig. Surg. 2004 21 : 297 304. (Pubitemid 39370395)
14. Gotzinger P, Wanser P, Barlan M, Soutner T, Jakesz R, Fugger F. Candida infection of local necrosis in severe acute pancreatitis is associated with increased mortality. Shock 2000 14 : 320 3.
15. Kujath P, Rosen Feldt M, Esnaashari H et al. Fungal infections in patients with necrotizing pancreatitis; risk factors, incidence, therapy. Mycoses 2005 48 (Suppl. 1 36 40. (Pubitemid 40592865)
16. King NK, Siriwardana HPP, Wood B, Siriwardena AK. Trends in fungal colonization of pancreatic necrosis in patients undergoing necrosectomy for acute pancreatitis. HPB (Oxford) 2005 7 : 120 23. (Pubitemid 40767047)
17. Farkas G, Marton J, Mandi Y, Leindler L. Surgical management and complex treatment of infected pancreatic necrosis: 18 year experience at a single center. J. Gastrointest. Surg. 2006 10 : 278 85.
18. He YM, Sheng XL, Ai Z-L et al. Prevention and therapy of fungal infection in severe acute pancreatitis: a prospective clinical study. World J. Gastroenterol. 2003 9 : 2619 24. (Pubitemid 37461283)
19. Dean DA, Burchard KW. Fungal infection in surgical patients. Am. J. Surg. 1996 171 : 374 82. (Pubitemid 26086712)
20. Balthazar EJ, Freeny PC, van Sonnenberg E. Imaging and intervention in acute pancreatitis. Radiology 1994 193 : 297 306. (Pubitemid 24338302)
21. Balthazar EJ, Robinson DL, Megibow AJ, Ranson JH. Acute pancreatitis: value of CT in establishing prognosis. Radiology 1990 174 : 331 36. (Pubitemid 20038583)
22. Bradley EL III. A clinically based classification system for acute pancreatitis. Summary of the international symposium on acute pancreatitis. Atlanta. Arch. Surg. 1993 128 : 586 90.
23. Berzin TM, Rocha FG, Whang EE et al. Prevalence of primary fungal infections in necrotizing pancreatitis. Pancreatology 2007 18 : 63 6. (Pubitemid 46725723)
24. Alverday J, Aoys E, Moss GS. Total parental nutrition promotes bacterial translocation from the gut. Surgery 1988 104 : 185 90. (Pubitemid 18205321)
25. Reddy MS, Jindal R, Gupta R, Yadav TD, Wig JD. Outcome after pancreatic necrosectomy: trends over 12 years at an Indian Centre. ANZ Surg 2006 76 : 704 9. (Pubitemid 44154741)