An efficient synthesis of a multipotent eicosanoid pathway modulator

Organic Process Research and Development

Volumn 13, Issue 2, 2009, Pages 268-275

  Yates, Matthew H ^a   Koenig, Thomas M ^a   Kallman, Neil J ^a   Ley, Christopher P ^a   Mitchell, David ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 65949088133     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op800257u     Document Type: Article

References (22)

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20. Although in Table 1 KOH with PTC gave slightly better results, it was not felt that the added complexity was worth the slight improvement in yield, especially since most of the yield loss was due to hydrolysis and not dimerization.
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