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Volumn 14, Issue 8, 2008, Pages 933-999

Exenatide use in the management of metabolic syndrome: A retrospective data base study

Author keywords

[No Author keywords available]

Indexed keywords

EXENDIN 4; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; ANTIDIABETIC AGENT; CHOLESTEROL; PEPTIDE; VENOM;

EID: 65849411794     PISSN: 1530891X     EISSN: None     Source Type: Journal    
DOI: 10.4158/ep.14.8.993     Document Type: Article
Times cited : (24)

References (38)
  • 1
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes. 1988;37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 0024391834 scopus 로고
    • The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension
    • Kaplan NM. The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch Intern Med. 1989;149:1514-1520.
    • (1989) Arch Intern Med , vol.149 , pp. 1514-1520
    • Kaplan, N.M.1
  • 3
    • 33644822875 scopus 로고
    • Visceral obesity: A civilization syndrome
    • Björntorp P. Visceral obesity: "a civilization syndrome." Obes Res. 1993;1:206-222.
    • (1993) Obes Res , vol.1 , pp. 206-222
    • Björntorp, P.1
  • 4
    • 0027092522 scopus 로고
    • Abdominal obesity and the metabolic syndrome
    • Björntorp P. Abdominal obesity and the metabolic syndrome. Ann Med. 1992;24:465-468.
    • (1992) Ann Med , vol.24 , pp. 465-468
    • Björntorp, P.1
  • 5
    • 0035897696 scopus 로고    scopus 로고
    • Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 6
    • 0034837376 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality associated with the metabolic syndrome
    • Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care. 2001;24:683-689.
    • (2001) Diabetes Care , vol.24 , pp. 683-689
    • Isomaa, B.1    Almgren, P.2    Tuomi, T.3
  • 8
    • 1842479594 scopus 로고    scopus 로고
    • Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women
    • Lee CC, Kasa-Vubu JZ, Supiano MA. Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women. Metabolism. 2004;53:507-512.
    • (2004) Metabolism , vol.53 , pp. 507-512
    • Lee, C.C.1    Kasa-Vubu, J.Z.2    Supiano, M.A.3
  • 9
    • 0024335677 scopus 로고
    • Importance of obesity for the metabolic abnormalities associated with an abdominal fat distribution
    • Landin K, Krotkiewski M, Smith U. Importance of obesity for the metabolic abnormalities associated with an abdominal fat distribution. Metabolism. 1989;38:572-576,
    • (1989) Metabolism , vol.38 , pp. 572-576
    • Landin, K.1    Krotkiewski, M.2    Smith, U.3
  • 10
    • 0037034257 scopus 로고    scopus 로고
    • Diabetes Prevention Program Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler WC, Barrett-Connor E, Fowler SE, et al; Diabetes Prevention Program Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 11
    • 0035799806 scopus 로고    scopus 로고
    • Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Tuomilehto J, Lindström J, Eriksson JG, et al; Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344: 1343-1350.
    • (2001) N Engl J Med , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1    Lindström, J.2    Eriksson, J.G.3
  • 12
    • 0037097039 scopus 로고    scopus 로고
    • STOP-NIDDM Trail Research Group. Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
    • Chiasson JL, Josse RG, Gomis R, et al; STOP-NIDDM Trail Research Group. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet. 2002;359:2072-2077.
    • (2002) Lancet , vol.359 , pp. 2072-2077
    • Chiasson, J.L.1    Josse, R.G.2    Gomis, R.3
  • 13
    • 15944395414 scopus 로고    scopus 로고
    • Diabetes Prevention Program Research Group. Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program
    • Knowler WC, Hamman RF, Edelstein SL, et al; Diabetes Prevention Program Research Group. Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. Diabetes. 2005;54:1150-1156.
    • (2005) Diabetes , vol.54 , pp. 1150-1156
    • Knowler, W.C.1    Hamman, R.F.2    Edelstein, S.L.3
  • 14
    • 33645470211 scopus 로고    scopus 로고
    • Drug therapy of the metabolic syndrome: Minimizing the emerging crisis in polypharmacy
    • Grundy SM Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy. Nat Rev Drug Discov. 2006;5:295-309.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 295-309
    • Grundy, S.M.1
  • 15
    • 3242730474 scopus 로고    scopus 로고
    • Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
    • Holst JJ, Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab. 2004;287: E199-E206.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Holst, J.J.1    Gromada, J.2
  • 16
    • 0031936954 scopus 로고    scopus 로고
    • Glucagon-like peptides
    • Drucker DJ. Glucagon-like peptides. Diabetes. 1998;47: 159-169.
    • (1998) Diabetes , vol.47 , pp. 159-169
    • Drucker, D.J.1
  • 17
    • 0141446228 scopus 로고    scopus 로고
    • Enhancing incretin action for the treatment of type 2 diabetes
    • Drucker DJ. Enhancing incretin action for the treatment of type 2 diabetes. Diabetes Care. 2003;26:2929-2940.
    • (2003) Diabetes Care , vol.26 , pp. 2929-2940
    • Drucker, D.J.1
  • 18
    • 0030048156 scopus 로고    scopus 로고
    • Bioactive peptides from lizard venoms
    • Raufman JP. Bioactive peptides from lizard venoms. Regul Pept. 1996;61:1-18.
    • (1996) Regul Pept , vol.61 , pp. 1-18
    • Raufman, J.P.1
  • 19
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • Göke R, Fehmann HC, Linn T, et al. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J Biol Chem. 1993; 268:19650-19655.
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3
  • 20
    • 0347360186 scopus 로고    scopus 로고
    • Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
    • Nielsen LL, Young AA, Parkes DG. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept. 2004;117:77-88.
    • (2004) Regul Pept , vol.117 , pp. 77-88
    • Nielsen, L.L.1    Young, A.A.2    Parkes, D.G.3
  • 21
    • 27744541052 scopus 로고    scopus 로고
    • Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
    • Fehse F, Trautmann M, Holst JJ, et al. Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab. 2005;90:5991-5997.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5991-5997
    • Fehse, F.1    Trautmann, M.2    Holst, J.J.3
  • 22
    • 20544476444 scopus 로고    scopus 로고
    • Exenatide improves glycemic control and reduces body weight in subjects with type 2 diabetes: A dose-ranging study
    • Poon T, Nelson P, Shen L, et al. Exenatide improves glycemic control and reduces body weight in subjects with type 2 diabetes: a dose-ranging study. Diabetes Technol Ther. 2005;7:467-477.
    • (2005) Diabetes Technol Ther , vol.7 , pp. 467-477
    • Poon, T.1    Nelson, P.2    Shen, L.3
  • 23
    • 15444367142 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus
    • Kolterman OG, Kim DD, Shen L, et al. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus. Am J Health Syst Pharm. 2005;62:173-181.
    • (2005) Am J Health Syst Pharm , vol.62 , pp. 173-181
    • Kolterman, O.G.1    Kim, D.D.2    Shen, L.3
  • 24
    • 0036959991 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
    • Nauck MA, Heimesaat MM, Behle K, et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab. 2002;87:1239-1246.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1239-1246
    • Nauck, M.A.1    Heimesaat, M.M.2    Behle, K.3
  • 25
    • 0038121744 scopus 로고    scopus 로고
    • Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
    • Vilsbøll T, Krarup T, Madsbad S, Holst JJ. Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regul Pept. 2003;114:115-121.
    • (2003) Regul Pept , vol.114 , pp. 115-121
    • Vilsbøll, T.1    Krarup, T.2    Madsbad, S.3    Holst, J.J.4
  • 26
    • 4344713643 scopus 로고    scopus 로고
    • Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia
    • Degn KB, Brock B, Juhl CB, et al. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia. Diabetes. 2004;53:2397-2403.
    • (2004) Diabetes , vol.53 , pp. 2397-2403
    • Degn, K.B.1    Brock, B.2    Juhl, C.B.3
  • 27
    • 0000385121 scopus 로고    scopus 로고
    • Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans
    • Schirra J, Sturm K, Leicht P, Arnold R, Göke B, Katschinski M. Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans. J Clin Invest. 1998;101:1421-1430.
    • (1998) J Clin Invest , vol.101 , pp. 1421-1430
    • Schirra, J.1    Sturm, K.2    Leicht, P.3    Arnold, R.4    Göke, B.5    Katschinski, M.6
  • 28
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • DeFronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care. 2005;28:1092-1100.
    • (2005) Diabetes Care , vol.28 , pp. 1092-1100
    • DeFronzo, R.A.1    Ratner, R.E.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 29
    • 7444228521 scopus 로고    scopus 로고
    • Exenatide-113 Clinical Study Group. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, et al; Exenatide-113 Clinical Study Group. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care. 2004;27:2628-2635.
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3
  • 30
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care. 2005;28:1083-1091.
    • (2005) Diabetes Care , vol.28 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3
  • 31
    • 0034814047 scopus 로고    scopus 로고
    • Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers
    • Edwards CM, Stanley SA, Davis R, et al Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers. Am J Physiol Endocrinol Metab. 2001;281:155-161.
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , pp. 155-161
    • Edwards, C.M.1    Stanley, S.A.2    Davis, R.3
  • 32
    • 0043264144 scopus 로고    scopus 로고
    • Emergence of metabolic syndrome in childhood: An epidemiological overview and mechanistic link to dyslipidemia
    • Kohen-Avramoglu R, Theriault A, Adeli K. Emergence of metabolic syndrome in childhood: An epidemiological overview and mechanistic link to dyslipidemia. Clin Biochem. 2003;36:413-420.
    • (2003) Clin Biochem , vol.36 , pp. 413-420
    • Kohen-Avramoglu, R.1    Theriault, A.2    Adeli, K.3
  • 33
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, et al. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes. Diabetes Obes Metab. 2006;8:436-447.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3
  • 34
    • 33947156808 scopus 로고    scopus 로고
    • Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials
    • Buse JB, Klonoff DC, Nielsen LL, et al Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials. Clin Ther. 2007;29:139-153.
    • (2007) Clin Ther , vol.29 , pp. 139-153
    • Buse, J.B.1    Klonoff, D.C.2    Nielsen, L.L.3
  • 35
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest. 1998;101:515-520.
    • (1998) J Clin Invest , vol.101 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 36
    • 0002300343 scopus 로고    scopus 로고
    • Glucagon-like peptide-1: A potent regulator of food intake in humans
    • Gutzwiller JP, Göke B, Drewe J, et al. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut. 1999;44:81-86.
    • (1999) Gut , vol.44 , pp. 81-86
    • Gutzwiller, J.P.1    Göke, B.2    Drewe, J.3
  • 37
    • 0032966882 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
    • Gutzwiller JP, Drewe J, Göke B, et al. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol. 1999;276: R1541-R1544.
    • (1999) Am J Physiol , vol.276
    • Gutzwiller, J.P.1    Drewe, J.2    Göke, B.3
  • 38
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the third National Health and Nutrition Examination Survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287:356-359.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3


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