Synaptic mRNAs are modulated by learning

Journal of Neuroscience Research

Volumn 87, Issue 9, 2009, Pages 1960-1968

  Ferrara, Eugenia ^a   Cefaliello, Carolina ^a   Eyman, Maria ^a   de Stefano, Rosanna ^a   Giuditta, Antonio ^a   Crispino, Marianna ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Active avoidance; Brain plasticity; Learning; mRNA; Synaptosomes

Indexed keywords

4 AMINOBUTYRIC ACID CARRIER; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN SYNAPTOSOME; CONTROLLED STUDY; FREEZING; GENE EXPRESSION; LEARNING; MALE; NERVE CELL PLASTICITY; NONHUMAN; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ANIMALS; ASTROCYTES; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BRAIN; CEREBELLUM; CEREBRUM; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GLIAL FIBRILLARY ACIDIC PROTEIN; LEARNING; MALE; NEURONS; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; RNA, MESSENGER; SYNAPTOSOMES; TRANSCRIPTIONAL ACTIVATION;

EID: 65849215034     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22037     Document Type: Article

References (32)

1. Alvarez J, Giuditta A, Koenig E. 2000. Protein synthesis in axons and terminals: significance for maintenance, plasticity and regulation of phenotype. With a critique of slow transport theory. Progr Neurobiol 62:1-62.
2. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
3. Casadio A, Martin KC, Giustetto M, Zhu H, Chen M, Bartsch D, Bailey CH, Kandel ER. 1999. A transient neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis. Cell 99:221-237.
4. Conti F, Melone M, De Biasi S, Minelli A, Brecha NC, Ducati A. 1998. Neuronal and glial localization of GAT-1, a high-affinity γ-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex. J Comp Neurol 396:51-63.
5. Conti F, Minelli A, Melone M. 2004. GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications. Brain Res Brain Res Rev 45:196-212.
6. Crispino M, Perrone Capano C, Aiello A, Iannetti E, Cupello A, Giuditta A. 2001. Messenger RNAs in synaptosomal fractions from rat brain. Mol Brain Res 97:171-176.
7. Cutillo V, Montagnese P, Gremo F, Casola L, Giuditta A. 1983. Origin of axoplasmic RNA in the squid giant fibre. Neurochem Res 8:1621-1634.
8. Eng LF, Ghimikar RS, Lee YL. 2000. Glial fibrillary acidic protein: GFAP - thirty-one years (1969-2000). Neurochem Res 25:1439-1451.
9. Eyman M, Cefaliello C, Ferrara E, De Stefano R, Crispino M, Giuditta A. 2007a. Synaptosomal protein synthesis is selectively modulated by learning. Brain Res 1132:148-157.
10. Eyman M, Cefaliello C, Ferrara E, De Stefano R, Scotto Lavina Z, Crispino M, Squillace A, van Minnen J, Kaplan BB, Giuditta A. 2007b. Local synthesis of RNA in axons and nerve terminals. Eur J Neurosci 25:341-350.
11. Giuditta A, Menichini E, Perrone Capano C, Langella M, Martin R, Castigli E, Kaplan BB. 1991. Active polysomes in the axoplasm of the squid giant axon. J Neurosci Res 26:18-28.
12. Giuditta A, Kaplan BB, van Minnen J, Alvarez J, Koenig E. 2002. Axonal and presynaptic protein synthesis: new insights into the biology of the neuron. Trends Neurosci 25:400-404.
13. Giuditta A, Chun JT, Eyman M, Cefaliello C, Bruno AP, Crispino M. 2008. Local gene expression in axons and nerve endings: the glia-neuron unit. Physiol Rev 88:515-555.
14. A-associated genes in the amygdala after the acquisition and extinction of Pavlovian fear. Eur J Neurosci 26:3631-3644.
15. Itouji A, Sakai N, Tanaka C, Saito N. 1996. Neuronal and glial localization of two GABA transporters (GAT1 and GAT3) in rat cerebellum. Mol Brain Res 37:309-316.
16. Kang H, Schuman EM. 1995. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 267:1658-1662.
17. Kinney GA, Spain WJ. 2002. Synaptically evoked transporter currents in neocortical glia. J Neurophysiol 88:2899-2908.
18. Koenig E, Giuditta A. 1999. Protein synthesizing machinery in the axon compartment. Neuroscience 89:5-15.
19. Landry CF, Watson JB, Kashima T, Campagnoni AT. 1994. Cellular influences on RNA sorting in neurons and glia: an in situ hybridization histochemical study. Brain Res Mol Brain Res 27:1-11.
20. Lyles V, Zhao Y, Martin KC. 2006. Synapse formation and mRNA localization in cultured Aplysia neurons. Neuron 49:349-356.
21. Mariucci G, Giuditta A, Ambrosini MV. 2007. Permanent brain ischemia induces marked increments in hsp72 expression and local protein synthesis in synapses of the ischemic hemisphere. Neurosci Lett 415:77-80.
22. Martin KC, Zukin RS. 2006. RNA trafficking and local protein synthesis in dendrites: an overview. J Neurosci 26:7131-7134.
23. Martin KC, Casadio A, Zhu H, Yaping E, Rose JC, Chen M, Bailey CH, Kandel ER. 1997. Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage. Cell 91:927-938.
24. Minelli A, Brecha NC, Karschin C, DeBiasi S, Conti F. 1995. GAT-1, a high affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex. J Neurosci 15:7734-7746.
25. Pernas-Alonso R, Morelli F, di Porzio U, Perrone-Capano C. 1999. Multiplex semi-quantitative reverse transcriptase-polymerase chain reaction of low abundance neuronal mRNAs. Brain Res Protoc 4:395-406.
26. Rao A, Steward O. 1991. Evidence that protein constituents of postsynaptic membrane specializations are locally synthesized: analysis of proteins synthesized within synaptosomes. J Neurosci 11:2881-2895.
27. Rapallino M V, Cupello A, Giuditta A. 1988. Axoplasmic RNA species synthesized in the isolated squid giant axon. Neurochem Res 13:625-631.
28. Schacher S, Wu F. 2002. Synapse formation in the absence of cell bodies requires protein synthesis. Neuroscience 22:1831-1839.
29. Stout JT, Caskey CT. 1985. HPRT: gene structure, expression, and mutation. Annu Rev Genet 19:127-148.
30. Swan M, Najlerahim A, Watson RE, Bennett JP. 1994. Distribution of mRNA for the GABA transporter GAT-1 in the rat brain: evidence that GABA uptake is not limited to presynaptic neurons. J Anat 185: 315-323.
31. Tobias GS, Koenig E. 1975. Axonal protein synthesizing activity during the early outgrowth period following neurotomy. Exp Neurol 49:221-234.
32. Whittaker VP. 1993. Thirty years of synaptosomes research. J Neurocytol 22:735-742.