A dose-ranging study of pramipexole for the symptomatic treatment of restless legs syndrome: Polysomnographic evaluation of periodic leg movements and sleep disturbance

Sleep Medicine

Volumn 10, Issue 6, 2009, Pages 630-636

  Jama, Leni ^a,e   Hirvonen, Kari ^a,b   Partinen, Markku ^a,e   Alakuijala, Anniina ^a,c   Hublin, Christer ^d,e   Tamminen, Ilkka ^f   Koester, Juergen ^g   Reess, Juergen ^g  

^a Rinnekoti Foundation Finland   (Finland)

^b Neurotest Tampere Oy   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^e UNIVERSITY OF HELSINKI   (Finland)

^f Boehringer Ingelheim Finland Ky   (Finland)

^g BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Dopamine agonist; Insomnia; Movement disorder; Periodic limb movements; Polysomnography; Pramipexole; Restless legs syndrome; Sleep disorders

Indexed keywords

PLACEBO; PRAMIPEXOLE;

ABDOMINAL DISCOMFORT; ADULT; AROUSAL; ARTICLE; BEDTIME DOSAGE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FATIGUE; FEMALE; FLU LIKE SYNDROME; HUMAN; INFLUENZA; MAJOR CLINICAL STUDY; MALE; NAUSEA; ORTHOSTATIC HYPOTENSION; PARALLEL DESIGN; PERIODIC LEG MOVEMENT; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RESTLESS LEGS SYNDROME; RHINOPHARYNGITIS; SELF EVALUATION; SLEEP DISORDER; SLEEP PARAMETERS; SLEEP TIME; WAKEFULNESS;

ADULT; AGED; BENZOTHIAZOLES; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LEG; MALE; MIDDLE AGED; MOVEMENT; POLYSOMNOGRAPHY; RESTLESS LEGS SYNDROME; TREATMENT OUTCOME;

EID: 65749120598     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2008.05.014     Document Type: Article

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