NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase

Neuroscience Letters

Volumn 459, Issue 2, 2009, Pages 79-83

  Braga, Andréa Arantes ^a   Aguiar, Daniele Cristina ^a   Guimarães, Francisco Silveira ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anxiety; Defense; DMSO; Flight responses; ODQ; Panic

Indexed keywords

6 (2 HYDROXY 1 METHYL 2 NITROSOHYDRAZINO) N METHYL 1 HEXANAMINE; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; NITRIC OXIDE DONOR; PEROXYNITRITE; PROTEIN NOC 9; PROTEIN SIN 1; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; ENZYME ACTIVITY; FLIGHT; IN VITRO STUDY; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT;

ANIMALS; CATHETERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESCAPE REACTION; GUANYLATE CYCLASE; MALE; MICROINJECTIONS; MOLSIDOMINE; MOTOR ACTIVITY; MULTIVARIATE ANALYSIS; NITRIC OXIDE DONORS; OXADIAZOLES; PERIAQUEDUCTAL GRAY; QUINOXALINES; RANDOM ALLOCATION; RATS; RATS, WISTAR; TIME FACTORS; TRIAZENES;

EID: 65749119210     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.05.009     Document Type: Article

References (31)

1. Aguiar D.C., and Guimarães F.S. Inhibition of nitric oxide synthase in the dorsolateral periaqueductal grey decreases behavioural consequences of predator exposure in rats. European Neuropsychopharmacology 16 (2006) S462-S463
2. Ambalavanan N., Mariani G., Bulger A., and Philips III J.B. Role of nitric oxide in regulating neonatal porcine pulmonary artery smooth muscle cell proliferation. Biology of the Neonate 76 (1999) 291-300
3. Bandler R., and Carrive P. Integrated defense reaction elicited by excitatory amino acid microinjection in the midbrain periaqueductal grey region of the unrestrained cat. Brain Research 439 (1988) 95-106
4. Bellamy T.C., Wood J., and Garthwaite J. On the activation of soluble guanylyl cyclase by nitric oxide. Proceedings of the National Academy of Sciences of the United States of America 99 (2002) 507-510
5. Brandão M.L., Zanoveli J.M., Ruiz-Martinez R.C., Oliveira L.C., and Landeira-Fernandez J. Different patterns of freezing behavior organized in the periaqueductal gray of rats: association with different types of anxiety. Behavioural Brain Research 188 (2008) 1-13
6. De Oliveira R.M.W., Del Bel E.A., and Guimarães F.S. Behavioral and c-fos expression changes induced by nitric oxide donors microinjected into the dorsal periaqueductal gray. Brain Research Bulletin 51 (2000) 457-464
7. De Oliveira R.M.W., Del Bel E.A., and Guimarães F.S. Effects of excitatory amino acids and nitric oxide on flight behavior elicited from the dorsal periaqueductal gray. Neuroscience Biobehavioral Reviews 25 (2001) 679-685
8. Deakin J.F., and Graeff F.G. 5-HT and mechanisms of defense. Journal of Psychopharmacology 5 (1991) 305-315
9. Del Carlo Jr. M., and Loeser R.F. Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis and Rheumatism 46 (2002) 394-403
10. Feelish M., Ostrowsky J., and Noack E. On the mechanisms of NO release form sydnonimines. Journal of Cardiovascular Pharmacology 14 (1989) S13-22
11. Fossum E.N., Lisowski M.J., Macey T.A., Ingram S.L., and Morgan M.M. Microinjection of the vehicle dimethyl sulfoxide (DMSO) into the periaqueductal gray modulates morphine antinociception. Brain Research 1204 (2008) 53-58
12. Garthwaite J. Glutamate, nitric oxide and cell-signaling in the nervous system. Trends in Neurosciences 14 (1991) 60-67
13. Gaudry-Talarmain M., Moulian N., Meunier F.A., Blanchard B., Angaut-Petit D., Faille L., and Ducrocq C. Nitric oxide and peroxynitrite affect differently acetylcholine release, choline acetyltransferase activity, synthesis and compartmention of newly formed acetylcholine in Torpedo mamorata synaptosomes. Nitric Oxide 1 (1997) 330-345
14. Goss S.P., Hogg N., and Kalyanaraman B. The effect of nitric oxide release rates on the oxidation of human low density lipoprotein. Journal of Biological Chemistry 272 (1997) 21647-21653
15. Graeff F.G. Neuroanatomy and neurotransmitter regulation of defensive behavior and related emotions in mammals. Brazilian Journal of Medical and Biological Research 27 (1994) 811-829
16. Guimarães F.S., Beijamini V., Moreira F.A., Aguiar D.C., and de Lucca A.C.B. Role of nitric oxide in brain regions related to defensive reactions. Neuroscience Biobehavioral Reviews 29 (2005) 1313-1322
17. Guimarães F.S., Carobrez A.P., De Aguiar J.C., and Graeff F.G. Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey. Psychopharmacology 103 (1991) 91-94
18. Guimarães F.S., de Aguiar J.C., Del Bel E.A., and Ballejo G. Anxiolytic effect of nitric oxide inhibitors microinjected into the dorsal central grey. NeuroReport 5 (1994) 1929-1932
19. Jenck F., Moreau J.L., and Martin J.R. Dorsal periaqueductal gray-induced aversion as a simulation of panic anxiety: elements of face and predictive validity. Psychiatry Research 57 (1995) 181-191
20. Krieger J.E., and Graeff F.G. Defensive behavior and hypertension induced by glutamate in the midbrain central grey of the rat. Brazilian Journal of Medical and Biological Research 18 (1985) 61-67
21. Matheus M.G., de Lacerda J., and Guimarães F.S. Behavioral effects of vehicle microinjected into the dorsal periaqueductal grey of rats tested in the elevated plus maze. Brazilian Journal of Medical and Biological Research 30 (1997) 61-64
22. Matheus M.G., and Guimarães F.S. Antagonism of non-NMDA receptors in the dorsal periaqueductal grey induces anxiolytic effect in the elevated plus maze. Psychopharmacology 132 (1997) 14-18
23. Molchanov M.L., and Guimarães F.S. Anxiolytic-like effects of AP7 injected into the dorsolateral or ventrolateral columns of the periaqueductal gray of rats. Psychopharmacology 160 (2002) 30-38
24. Moreira F.A., Aguiar D.C., and Guimarães F.S. Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. Neuropharmacology 52 (2007) 958-965
25. Moreira F.A., Molchanov M.L., and Guimarães F.S. Ionotropic glutamate-receptor antagonists inhibit the aversive effects of nitric oxide donor injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology 171 (2004) 199-203
26. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 3rd ed. (1997), Academic Press, San Diego
27. Scheighofer N., and Ferriol G. Diffusion of nitric oxide can facilitate cerebellar learning: a simulation study. Proceedings of the National Academy of Sciences of the United States of America 97 (2000) 10661-10665
28. Schenberg L.C., Bittencourt A.S., Sudré E.C.M., and Vargas L.C. Modeling panic attacks. Neuroscience Biobehavioral Reviews 25 (2001) 647-659
29. 2+-induced LDL oxidation by nitric oxide: a study using donors with different half-time of NO release. Biochemical and Biophysical Research Communications 220 (1996) 306-309
30. Tavares R.F., Resstel L.B., and Corrêa F.M. Interaction between glutamatergic and nitrergic mechanisms mediating cardiovascular responses to l-glutamate injection in the diagonal band of Broca in anesthetized rats. Life Sciences 81 (2007) 855-862
31. Volke V., Wegener G., and Vassar E. Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice. Journal of Physiology Pharmacology 54 (2003) 653-660