A single systemic transient hypotension induces long-term changes in rats' MRI parameters and behavior: Relation to aging

Neurological Research

Volumn 31, Issue 3, 2009, Pages 304-312

  Plaschke, Konstanze ^a,c   Frauenknecht, Katrin ^b   Sommer, Clemens ^b   Heiland, Sabine ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Aging; Cognition; MRI; Oligemia; Rat brain

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BRAIN INJURY; BRAIN REGION; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFUSION WEIGHTED IMAGING; HEMORRHAGIC HYPOTENSION; HYPOTENSION; ISCHEMIA; LOCOMOTION; LONGITUDINAL STUDY; MALE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT; REFERENCE MEMORY; STRUCTURE ANALYSIS;

AGING; ANIMALS; CORPUS STRIATUM; DIFFUSION MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HYPOTENSION; HYPOVOLEMIA; MALE; MEMORY; MOTOR ACTIVITY; RATS; RATS, WISTAR; SHOCK, HEMORRHAGIC; TIME FACTORS;

EID: 65749102899     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/174313209X385653     Document Type: Article

References (34)

1. Plassman BL, Langa KM, Fisher GG, et al. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med 2008; 148: 427-434
2. Morrison JH, Hof PR. Life and death of neurons in the aging brain. Science 1997; 278: 412-419 (Pubitemid 27454417)
3. Geschwind N. Disconnection syndromes in animals and man. Brain 1965; 88: 237-294
4. Bullmore ET, Rabe-Hesketh S, Morris RG, et al. Functional magnetic resonance image analysis of a large-scale neurocognitive network. Neuroimage 1996; 4: 16-33 (Pubitemid 26303613)
5. Guo AC, MacFall JR, Provenzale JM. Multiple sclerosis: Diffusion tensor MR imaging for evaluation of normal-appearing white matter. Radiology 2002; 222: 729-736 (Pubitemid 34215221)
6. Mintorovitch J, Moseley ME, Chileuitt L, et al. Comparison of diffusion- and T2-weighted MRI for the early detection of cerebral ischemia and reperfusion in rats. Magn Reson Med 1991; 18: 39-50 (Pubitemid 20248617)
7. Lansberg MG, Thijs VN, O'Brien MW, et al. Evolution of apparent diffusion coefficient, diffusion-weighted and T2-weighted signal intensity of acute stroke. AJNR Am J Neuroradiol 2001; 22: 637-644
8. Oppenheim C, Lamy C, Touzé E, et al. Do transient ischemic attacks with diffusion-weighted imaging abnormalities correspond to brain infarctions? AJNR Am J Neuroradiol 2006; 27: 1782-1787
9. Kamal AK, Segal AZ, Ulug AM. Quantitative diffusion-weighted MR imaging in transient ischemic attacks. AJNR Am J Neuroradiol 2002; 23: 1533-1538 (Pubitemid 35154994)
10. Hoehn-Berlage M, Eis M, Back T, et al. Changes of relaxation times (T1, T2) and apparent diffusion coefficient after permanent middle cerebral artery occlusion in the rat: Temporal evolution, regional extent, and comparison with histology. Magn Reson Med 1995; 34: 824-834
11. Plaschke K, Bardenheuer HJ, Martin E, et al. Evolution of apparent diffusion coefficient and relaxation time (T2) in the subchronic stage of global cerebral oligemia in different rat models. Exp Brain Res 2006; 169: 361-368
12. Plaschke K, Yun SW, Martin E, et al. Interrelation between cerebral energy metabolism and behaviour in a rat model of permanent brain vessel occlusion. Brain Res 1999; 830: 320-329 (Pubitemid 29297960)
13. van der Staay FJ, van Nies J, Raaijmakers W. The effects of aging in rats on working and reference memory performance in a spatial holeboard discrimination task. Behav Neural Biol 1990; 53: 356-370 (Pubitemid 20175796)
14. Miyasaka N, Nagaoka T, Kuroiwa T, et al. Histopathologic correlates of temporal diffusion changes in a rat model of cerebral hypoxia/ischemia. AJNR Am J Neuroradiol 2000; 21: 60-66 (Pubitemid 30225828)
15. Rojas S, Martín A, Justicia C, et al. Modest MRI signal intensity changes precede delayed cortical necrosis after transient focal ischemia in the rat. Stroke 2006; 37: 1525-1532
16. Lythgoe MF, Thomas DL, Calamante F, et al. Acute changes in MRI diffusion, perfusion, T(1), and T(2) in a rat model of oligemia produced by partial occlusion of the middle cerebral artery. Magn Reson Med 2000; 44: 706-712
17. Chun T, Filippi CG, Zimmerman RD, et al. Diffusion changes in the aging human brain. AJNR Am J Neuroradiol 2000; 21: 1078-1083
18. Yoon B, Shim YS, Lee KS, et al. Region-specific changes of cerebral white matter during normal aging: A diffusion-tensor analysis. Arch Gerontol Geriatr 2008; 47: 129-138
19. Helenius J, Soinne L, Perkio J, et al. Diffusion-weighted MR imaging in normal human brains in various age groups. AJNR Am J Neuroradiol 2002; 23: 194-199
20. Heiland S, Sartor K, Martin E, et al. In vivo monitoring of agerelated changes in rat brain using quantitative diffusion magnetic resonance imaging and magnetic resonance relaxometry. Neurosci Lett 2002, 334: 157-160
21. Sykova E, Mazel T, Simonova Z, et al. Diffusion constraints and neuron-glia interaction during aging. Exp Gerontol 1998; 33: 837-851
22. Van der Toorn A, Syková E, Dijkhuizen RM, et al. Dynamic changes in water ADC, energy metabolism, extracellular space volume, and tortuosity in neonatal rat brain during global ischemia. Magn Reson Med 1996; 36: 52-60 (Pubitemid 26196531)
23. Vorísek I, Hájek M, Tintera J, et al. Water ADC, extracellular space volume, and tortuosity in the rat cortex after traumatic injury. Magn Reson Med 2002; 48: 994-1003
24. Siemonsen S, Finsterbusch J, Matschke J, et al. Age-dependent normal values of T2* and T2' in brain parenchyma. AJNR Am J Neuroradiol 2008; 29: 950-955
25. Drayer BP. Imaging of the aging brain. Part I. Normal findings. Radiology 1988; 166: 785-796
26. Frackowiak RS, Wise RJ, Gibbs JM, et al. Oxygen extraction in the aging brain. Monogr Neural Sci 1984; 11: 118-122
27. Buchweitz-Milton E, Weiss HR. Cerebral oxygen consumption and blood flow in Fischer-344 rats of different ages. Neurobiol Aging 1987; 8: 55-60 (Pubitemid 17034566)
28. Jones TA, Bury SD, Adkins-Muir DL, et al. Importance of behavioral manipulations and measures in rat models of brain damage and brain repair. ILAR J 2003; 44: 144-152
29. Plaschke K, Sommer C, Fahrner A, et al. Pronounced arterial collateralization was induced after permanent rat cerebral four-vessel occlusion. Relation to neuropathology and capillary ultrastructure. J Neural Transm 2003; 110: 719-732
30. Hoyer S, Plaschke K. The aging brain - The burden of life (?). In: Herdegen T, Delgado-Garcia J, eds. Brain: Damage and Repair. From Molecular Research to Clinical Therapy, New York: Kluwer Academic Press, 2004: pp. 1-21
31. Fischer B, Popa-Wagner A. Synaptic plasticity is preserved in the temporal cortex of 20-month-old rats. Arch Gerontol Geriatr 1997; 25: 27-39 (Pubitemid 27213993)
32. Lövblad KO, Delavelle J, Wetzel S, et al. ADC mapping of the aging frontal lobes in mild cognitive impairment. Neuroradiology 2004; 46: 282-286
33. Ray KM, Wang H, Chu Y, et al. Mild cognitive impairment: Apparent diffusion coefficient in regional gray matter and white matter structures. Radiology 2006; 241: 197-205
34. Kiriyama T, Tanizawa E, Hirano M, et al. SPECT revealed cortical dysfunction in a patient who had genetically definite megalencephalic leukoencephalopathy with subcortical cysts. Clin Neurol Neurosurg 2007; 109: 526-530