Radiation pneumonitis in patients treated for malignant pulmonary lesions with hypofractionated radiation therapy

Radiotherapy and Oncology

Volumn 91, Issue 3, 2009, Pages 307-313

  Borst, Gerben R ^a   Ishikawa, Masayori ^b   Nijkamp, Jasper ^a   Hauptmann, Michael ^a   Shirato, Hiroki ^b   Onimaru, Rikiya ^b   van den Heuvel, Michel M ^a   Belderbos, Jose ^a   Lebesque, Joos V ^a   Sonke, Jan Jakob ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Dose response analysis; Hypofractionated radiation therapy; Radiation pneumonitis; Stereotactic body radiation therapy

Indexed keywords

ARTICLE; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL STUDY; COMPARATIVE STUDY; CONTROLLED STUDY; CONVENTIONAL FRACTIONATED RADIATION THERAPY; DOSE RESPONSE; HUMAN; INCIDENCE; LUNG CANCER; MAJOR CLINICAL STUDY; PREDICTION; PRIORITY JOURNAL; PROBABILITY; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION PNEUMONIA; STATISTICAL MODEL; STEREOTACTIC BODY RADIATION THERAPY;

ADULT; CHI-SQUARE DISTRIBUTION; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; INCIDENCE; LIKELIHOOD FUNCTIONS; LUNG NEOPLASMS; MALE; NEOPLASM STAGING; RADIATION PNEUMONITIS; RADIOSURGERY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RISK FACTORS; TREATMENT OUTCOME;

EID: 65649150758     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2009.02.003     Document Type: Article

References (39)

1. Blomgren H., Lax I., Naslund I., et al. Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator. Clinical experience of the first thirty-one patients. Acta Oncol 34 (1995) 861-870
2. Onishi H., Araki T., Shirato H., et al. Stereotactic hypofractionated high-dose irradiation for stage I nonsmall cell lung carcinoma: clinical outcomes in 245 subjects in a Japanese multiinstitutional study. Cancer 101 (2004) 1623-1631
3. Onishi H., Shirato H., Nagata Y., et al. Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage I non-small cell lung cancer: updated results of 257 patients in a Japanese multi-institutional study. J Thorac Oncol 2 (2007) S94-S100
4. Wulf J., Haedinger U., Oppitz U., et al. Stereotactic radiotherapy for primary lung cancer and pulmonary metastases: a noninvasive treatment approach in medically inoperable patients. Int J Radiat Oncol Biol Phys 60 (2004) 186-196
5. Timmerman R.D., Kavanagh B.D., Cho L.C., et al. Stereotactic body radiation therapy in multiple organ sites. J Clin Oncol 25 (2007) 947-952
6. Timmerman R., McGarry R., Yiannoutsos C., et al. Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer. J Clin Oncol 24 (2006) 4833-4839
7. Lagerwaard F.J., Haasbeek C.J., Smit E.F., et al. Outcomes of risk-adapted fractionated stereotactic radiotherapy for stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 70 (2008) 685-692
8. Brock J., Ashley S., Bedford J., et al. Review of hypofractionated small volume radiotherapy for early-stage non-small cell lung cancer 1. Clin Oncol (R Coll Radiol) 20 (2008) 666-676
9. Yamashita H., Nakagawa K., Nakamura N., et al. Exceptionally high incidence of symptomatic grade 2-5 radiation pneumonitis after stereotactic radiation therapy for lung tumors. Radiat Oncol 2 (2007) 21
10. Guckenberger M., Heilman K., Wulf J., et al. Pulmonary injury and tumor response after stereotactic body radiotherapy (SBRT): results of a serial follow-up CT study. Radiother Oncol 85 (2007) 435-442
11. Zimmermann F.B., Geinitz H., Schill S., et al. Stereotactic hypofractionated radiotherapy in stage I (T1-2 N0 M0) non-small-cell lung cancer (NSCLC). Acta Oncol 45 (2006) 796-801
12. Aoki T., Nagata Y., Negoro Y., et al. Evaluation of lung injury after three-dimensional conformal stereotactic radiation therapy for solitary lung tumors: CT appearance 106. Radiology (2003)
13. Nagata Y., Takayama K., Matsuo Y., et al. Clinical outcomes of a phase I/II study of 48 Gy of stereotactic body radiotherapy in 4 fractions for primary lung cancer using a stereotactic body frame. Int J Radiat Oncol Biol Phys 63 (2005) 1427-1431
14. McGarry R.C., Papiez L., Williams M., et al. Stereotactic body radiation therapy of early-stage non-small-cell lung carcinoma: phase I study. Int J Radiat Oncol Biol Phys 63 (2005) 1010-1015
15. Semenenko V.A., and Li X.A. Lyman-Kutcher-Burman NTCP model parameters for radiation pneumonitis and xerostomia based on combined analysis of published clinical data. Phys Med Biol 53 (2008) 737-755
16. Onimaru R., Fujino M., Yamazaki K., et al. Steep dose-response relationship for stage I non-small-cell lung cancer using hypofractionated high-dose irradiation by real-time tumor-tracking radiotherapy. Int J Radiat Oncol Biol Phys 70 (2008) 374-381
17. Belderbos J.S., Heemsbergen W.D., De Jaeger K., et al. Final results of a phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys 66 (2006) 126-134
18. Lebesque J.V., and Keus R.B. The simultaneous boost technique: the concept of relative normalized total dose. Radiother Oncol 22 (1991) 45-55
19. Douglas B.G., and Fowler J.F. The effect of multiple small doses of X-rays on skin reactions in the mouse and a basic interpretation. Radiat Res 66 (1976) 401-426
20. Kwa S.L., Lebesque J.V., Theuws J.C., et al. Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys 42 (1998) 1-9
21. De Jaeger K., Hoogeman M.S., Engelsman M., et al. Incorporating an improved dose-calculation algorithm in conformal radiotherapy of lung cancer: re-evaluation of dose in normal lung tissue. Radiother Oncol 69 (2003) 1-10
22. Clayton D., and Hills M. Statistical models in epidemiology (1993), Oxford University Press, New York
23. Seppenwoolde Y., Lebesque J.V., De Jaeger K., et al. Comparing different NTCP models that predict the incidence of radiation pneumonitis. Normal tissue complication probability. Int J Radiat Oncol Biol Phys 55 (2003) 724-735
24. Venzon D.J., and Moolgavkar S.H. A method for computing profile-likelihood-based confidence intervals. Appl Stat 37 (1988) 87-94
25. Hosmer D., and Lemeshow S. Goodness of fit tests for the multiple logistic regression model. Commun Stat - Theory Models A9 (1980) 1043-1069
26. Ng A.W., Tung S.Y., and Wong V.Y. Hypofractionated stereotactic radiotherapy for medically inoperable stage I non-small cell lung cancer-report on clinical outcome and dose to critical organs. Radiother Oncol 87 (2008) 24-28
27. Gershkevitsh E., Schmidt R., Velez G., et al. Dosimetric verification of radiotherapy treatment planning systems: results of IAEA pilot study. Radiother Oncol (2008)
28. Graham M.V., Purdy J.A., Emami B., et al. Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys 45 (1999) 323-329
29. Franko A.J., and Sharplin J. Development of fibrosis after lung irradiation in relation to inflammation and lung function in a mouse strain prone to fibrosis. Radiat Res 140 (1994) 347-355
30. Trott K.R., Herrmann T., and Kasper M. Target cells in radiation pneumopathy. Int J Radiat Oncol Biol Phys 58 (2004) 463-469
31. Borst G.R., De Jaeger K., Belderbos J.S., et al. Pulmonary function changes after radiotherapy in non-small-cell lung cancer patients with long-term disease-free survival. Int J Radiat Oncol Biol Phys 62 (2005) 639-644
32. Baumann P., Nyman J., Hoyer M., et al. Stereotactic body radiotherapy for medically inoperable patients with stage I non-small cell lung cancer - a first report of toxicity related to COPD/CVD in a non-randomized prospective phase II study. Radiother Oncol 88 (2008) 359-367
33. Terry N.H., Tucker S.L., and Travis E.L. Residual radiation damage in murine lung assessed by pneumonitis. Int J Radiat Oncol Biol Phys 14 (1988) 929-938
34. Okamoto Y., Murakami M., Yoden E., et al. Reirradiation for locally recurrent lung cancer previously treated with radiation therapy. Int J Radiat Oncol Biol Phys 52 (2002) 390-396
35. Fowler J.F. The first James Kirk memorial lecture. What next in fractionated radiotherapy?. Br J Cancer Suppl 6 (1984) 285-300
36. Tucker S.L. Tests for the fit of the linear-quadratic model to radiation isoeffect data. Int J Radiat Oncol Biol Phys 10 (1984) 1933-1939
37. Steel GG. Basic clinical radiobiology, text book. Hodder Arnold, ISBN 0-340-80783-0 3rd ed. 1997.
38. Guerrero M., and Li X.A. Extending the linear-quadratic model for large fraction doses pertinent to stereotactic radiotherapy. Phys Med Biol 49 (2004) 4825-4835
39. Park C., Papiez L., Zhang S., et al. Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy. Int J Radiat Oncol Biol Phys 70 (2008) 847-852