An overview: From discovery of candidate mutations to disease modeling and transformation mechanisms of acute leukemia

Methods in Molecular Biology

Volumn 538, Issue , 2009, Pages 1-5

  So, Chi Wai Eric ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Acute leukemia; Disease modeling; Epigenetics; Epigenome; Hematopoiesis; Leukemic stem cells; Self renewal; Transcription factors

Indexed keywords

TUMOR PROTEIN;

ACUTE DISEASE; ANIMAL; CELL TRANSFORMATION; DISEASE MODEL; GENETICS; HUMAN; LEUKEMIA; MUTATION; PATHOLOGY; REVIEW;

ACUTE DISEASE; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; HUMANS; LEUKEMIA; MUTATION; NEOPLASM PROTEINS;

EID: 65649142975     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-418-6_1     Document Type: Review

References (5)

1. Look AT. (1997). Oncogenic transcription factors in the human acute leukemias. Science; 278 (5340): 1059-64. (Pubitemid 27517875)
2. Huntly BJ, Gilliland DG. (2005). Leukaemia stem cells and the evolution of cancer-stem-cell research. Nat Rev Cancer; 5 (4): 311-21. (Pubitemid 40488636)
3. Pina C, Enver T. (2007). Differential contributions of haematopoietic stem cells to foetal and adult haematopoiesis: insights from functional analysis of transcriptional regulators. Oncogene; 26 (47): 6750-65. (Pubitemid 47585100)
4. Greaves MF, Wiemels J. (2003). Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer; 3 (9): 639-49. (Pubitemid 37328819)
5. Rice KL, Hormaeche I, Licht JD. (2007). Epigenetic regulation of normal and malignant hematopoiesis. Onco-gene; 26 (47): 6697-714. (Pubitemid 47585096)